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6 papers found.
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Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer

novel ceRNA regulatory pathway in which PVT1 upregulates HK2 expression by sponging miR-143. Thus, PVT1 is potentially a novel therapeutic target for GBC patients. Notes Jianan Chen, Yan Yu and Hua Li

CD146 is essential for PDGFRβ-induced pericyte recruitment

. Jianan Chen and Yongting Luo have contributed equally to this work. Electronic supplementary material The online version of this article (doi:10.1007/s13238-017-0484-5) contains supplementary material

Design of LQG Controller for Active Suspension without Considering Road Input Signals

As the road conditions are completely unknown in the design of a suspension controller, an improved linear quadratic and Gaussian distributed (LQG) controller is proposed for active suspension system without considering road input signals. The main purpose is to optimize the vehicle body acceleration, pitching angular acceleration, displacement of suspension system, and tire...

miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-κB/XIAP axis

Jianan Chen, Feihu Yan & Yanqiao ZhangTranslation Medicine Research and Cooperation Center of Northern China, Heilongjiang Academy of Medical Sciences, Harbin, 150000, ChinaCi Zhao, Qi Zhao & Xiaoyi ... Scholar Search for Jianan Chen in:Nature Research journals • PubMed • Google Scholar Search for Feihu Yan in:Nature Research journals • PubMed • Google Scholar Search for Yanqiao Zhang in:Nature Research

CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development

Angiogenesis, a process that newly-formed blood vessels sprout from pre-existing ones, is vital for vertebrate development and adult homeostasis. Previous studies have demonstrated that the neuronal guidance molecule netrin-1 participates in angiogenesis and morphogenesis of the vascular system. Netrin-1 exhibits dual activities in angiogenesis: either promoting or inhibiting...

CD146 Deletion in the Nervous System Impairs Appetite, Locomotor Activity and Spatial Learning in Mice

Cell adhesion molecules (CAMs) are crucial effectors for the development and maintenance of the nervous system. Mutations in human CAM genes are linked to brain disorders and psychological diseases, and CAM knockout mice always exhibit similar behavioral abnormalities. CD146 is a CAM of the immunoglobulin superfamily that interacts with Neurite Outgrowth Factor and involved in...