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Search: authors:"Jianrui Song"

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Involvement of proapoptotic genes in autophagic cell death induced by irradiation

of Biochemistry and Molecular Biology, Soochow University Medical College, Suzhou, Jiangsu 215123, ChinaYanling Zhang AuthorsSearch for Jianrui Song in:Nature Research journals • PubMed • Google

Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells

Background Chemoresistance is one of the main obstacles to successful cancer therapy and is frequently associated with Multidrug resistance (MDR). Many different mechanisms have been suggested to explain the development of an MDR phenotype in cancer cells. One of the most studied mechanisms is the overexpression of P-glycoprotein (P-gp), which is a product of the MDR1 gene. Tumor...