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Current challenges and solutions of de novo assembly

BackgroundNext-generation sequencing (NGS) technologies have fostered an unprecedented proliferation of high-throughput sequencing projects and a concomitant development of novel algorithms for the assembly of short reads. However, numerous technical or computational challenges in de novo assembly still remain, although many new ideas and solutions have been suggested to tackle...

Which is Better for Patients with Breast Cancer: Totally Implanted Vascular Access Devices (TIVAD) or Peripherally Inserted Central Catheter (PICC)?

BackgroundOur aim was to compare the applications of totally implanted vascular access devices (TIVAD) and peripherally inserted central catheter (PICC) in breast cancer patients.MethodsWe analyzed 4080 cases of TIVAD and 1433 cases of PICC at the Breast Center of the Fourth Hospital of Hebei Medical University. The success rate, operation time, and procedures of catheterization...

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

New Algorithms for Edge Induced K\"onig-Egerv\'ary Subgraph Based on Gallai-Edmonds Decomposition

, trees, and flowers . Canadian Journal of Mathematics , 17 ( 3 ): 449 - 467 , 1965 . Qilong Feng , Senmin Zhu, and Jianxin Wang . A New Kernel for Parameterized MaxBisection Above Tight Lower Bound . In

Comparative proteomic analysis of Ulva prolifera response to high temperature stress

Ulva prolifera belongs to green macroalgae and is the dominant species of green tide. It is distributed worldwide and is therefore subject to high-temperature stress during the growth process. However, the adaptation mechanisms of the response of U. prolifera to high temperatures have not been clearly investigated yet. In this study, isobaric tags for relative and absolute...

Biomolecular Networks for Complex Diseases

developed methods. Fang-Xiang Wu Jianxin Wang Min Li Haiying Wang Advances in ns Hindawi www.hindawi.com Journal of bability and Statistics Hindawi www.hindawi.com Hindawi www.hindawi.com Hindawi

Biomolecular Networks for Complex Diseases

developed methods. Fang-Xiang Wu Jianxin Wang Min Li Haiying Wang

An Improved FPT Algorithm for the Flip Distance Problem

algorithms . Algorithmica , 40 ( 2 ): 83 - 97 , 2004 . doi: 10 .1007/ s00453-004-1096-z. Jianer Chen , Chao Xu, and Jianxin Wang . Dealing with 4-variables by resolution: An improved maxsat algorithm . Theor ... . Triangulations in CAGD . IEEE Computer Graphics and Applications , 13 ( 1 ): 47 - 52 , 1993 . doi: 10 .1109/38.180117. Feng Shi , Jianxin Wang , Yufei Yang , Qilong Feng, Weilong Li , and Jianer Chen . A fixed

Automatic Image-Based Plant Disease Severity Estimation Using Deep Learning

Automatic and accurate estimation of disease severity is essential for food security, disease management, and yield loss prediction. Deep learning, the latest breakthrough in computer vision, is promising for fine-grained disease severity classification, as the method avoids the labor-intensive feature engineering and threshold-based segmentation. Using the apple black rot images...

Automatic Image-Based Plant Disease Severity Estimation Using Deep Learning

100083, China Correspondence should be addressed to Yu Sun; nc.ude.ufjb@vynus and Jianxin Wang; nc.ude.ufjb@xjgnaw Received 8 March 2017; Revised 9 May 2017; Accepted 4 June 2017; Published 5 July 2017

SDTRLS: Predicting Drug-Target Interactions for Complex Diseases Based on Chemical Substructures

It is well known that drug discovery for complex diseases via biological experiments is a time-consuming and expensive process. Alternatively, the computational methods provide a low-cost and high-efficiency way for predicting drug-target interactions (DTIs) from biomolecular networks. However, the current computational methods mainly deal with DTI predictions of known drugs...

Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

Hepatocellular carcinoma (HCC) is a fatal disease and patients with HCC frequently die from metastasis. The mechanisms of HCC metastasis are not completely understood. In the present study, in vitro and in vivo data showed that HCC cells promoted cancer cell proliferation and lung metastases formation in a paracrinal/endocrinal way. We found that HCC-derived exosomes mediated...

TEMs but not DKK1 could serve as complementary biomarkers for AFP in diagnosing AFP-negative hepatocellular carcinoma

administration: Liping Mao, Yueguo Wang. Resources: Shouzhong Fu, Jianxin Wang. Software: Delin Wang, Gang Han. Validation: Shouzhong Fu, Jianxin Wang. Writing ± original draft: Liping Mao. Writing ± review

Complex Brain Network Analysis and Its Applications to Brain Disorders: A Survey

of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, Canada S7N5A9 Correspondence should be addressed to Jianxin Wang; nc.ude.usc.liam@gnawxj Received 26 April 2017; Revised 18