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Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells

Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells Jie Wang,1,2 Miao Li,2 Xiaolin Cui,1 Dongyue Lv,1 Lingling Jin,1 Muhammad Khan,3 Tonghui Ma1 ... project. Jie Wang, Miao Li, Xiaolin Cui, Dongyue Lv, and Lingling Jin conducted the experiments. Data were analyzed by Muhammad Khan and Tonghui Ma. The manuscript was written by Jie Wang and approved by

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo

Delta-6-desaturase inhibitor enhances radiation therapy in glioblastoma in vitro and in vivo Jie Wang,1 Huaxin Liang,2 Meiyan Sun,3 Lei Zhang,3 Huijing Xu,3 Wei Liu,3 Yan Li,3 Yue Zhou,4 Yingya Li,5

Ectomycorrhizal fungi reduce the light compensation point and promote carbon fixation of Pinus thunbergii seedlings to adapt to shade environments

We examined the effects of three ectomycorrhizal (ECM) symbionts on the growth and photosynthesis capacity of Japanese black pine (Pinus thunbergii) seedlings and estimated physiological and photosynthetic parameters such as the light compensation point (LCP), biomass, and phosphorus (Pi) concentration of P. thunbergii seedlings. Through this investigation, we documented a new...

Multiferroic Phases and Transitions in Ferroelectric Lead Titanate Nanodots

Discovery of novel phases and their associated transitions in low-dimensional nanoscale systems is of central interest as the origin of emergent phenomena and new device paradigms. Although typical ferroelectrics such as PbTiO3 exhibit diverse phase transition sequences, the conventional incompatible mechanisms of ferroelectricity and magnetism keep them as simply nonmagnetic...

Computer-Based Cognitive Programs for Improvement of Memory, Processing Speed and Executive Function during Age-Related Cognitive Decline: A Meta-Analysis

Background Several studies have assessed the effects of computer-based cognitive programs (CCP) in the management of age-related cognitive decline, but the role of CCP remains controversial. Therefore, this systematic review evaluated the evidence on the efficacy of CCP for age-related cognitive decline in healthy older adults. Methods Six electronic databases (through October...

Differential radio map-based robust indoor localization

While wireless local area network-based indoor localization is attractive, the problems concerning how to capture the signal-propagating character in the complex dynamic environment and how to accommodate the receiver gain difference of different mobile devices are challenging. In this article, we solve these problems by modeling them as common mode noise and develop a...

The response and recovery of the Arabidopsis thaliana transcriptome to phosphate starvation

Background Over application of phosphate fertilizers in modern agriculture contaminates waterways and disrupts natural ecosystems. Nevertheless, this is a common practice among farmers, especially in developing countries as abundant fertilizers are believed to boost crop yields. The study of plant phosphate metabolism and its underlying genetic pathways is key to discovering...

Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse

Tetsuro Izumi Hiromi Yokota-Hashimoto Shengli Zhao Jie Wang Philippe A. Halban Toshiyuki Takeuchi - sis in response to ER stress (10,11). Thus these findings indicate that the CHOP-dependent cell

Genome-wide association study identifies three novel loci for type 2 diabetes

Chen Peng Cheng Hu Ronald C. W. Ma Minako Imamura Minoru Iwata Tatsuhiko Tsunoda Takashi Morizono Nobuhiro Shojima Wing Yee So Ting Fan Leung Patrick Kwan Rong Zhang Jie Wang Weihui Yu Hiroshi Maegawa