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78 papers found.
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Astrocytoma progression scoring system based on the WHO 2016 criteria

Diffuse astrocytoma (including glioblastoma) is morbid with a worse prognosis than other types of glioma. Therefore, we sought to build a progression-associated score to improve malignancy and prognostic predictions for astrocytoma. The astrocytoma progression (AP) score was constructed through bioinformatics analyses of the training cohort (TCGA RNA-seq) and included 18 genes...

Giant magnetoelectric effect at the graphone/ferroelectric interface

SIOX. Author information Author notes Jie Wang and Yajun Zhang contributed equally. AffiliationsDepartment of Engineering Mechanics & Key Laboratory of Soft Machines and Smart Devices of Zhejiang ... Shanghai Materials Genome Institute, Shanghai University, 99 Shangda Road, Shanghai, 200444, ChinaTong-Yi Zhang AuthorsSearch for Jie Wang in:Nature Research journals • PubMed • Google Scholar Search for

Macular assessment of preoperative optical coherence tomography in ageing Chinese undergoing routine cataract surgery

This retrospective consecutive case series aimed to evaluate spectral-domain optical coherence tomography (SD-OCT) for occult macular disease recognition preoperatively in patients scheduled for routine cataract surgery. All patients scheduled for cataract surgery underwent macular SD-OCT. Scans were reviewed for retinal, retinal pigment epithelium and vitreomacular interface...

Fault-Tolerant Control of ANPC Three-Level Inverter Based on Order-Reduction Optimal Control Strategy under Multi-Device Open-Circuit Fault

; Chun-Jie Wang Carried out the experiment; Fang-Li Lin dealt with the experiment waveforms; Shi-Xiang Li made the article typesetting. Additional Information Competing Interests: The authors declare

KIF15 promotes pancreatic cancer proliferation via the MEK–ERK signalling pathway

Background:Pancreatic cancer is highly malignant and characterised by rapid and uncontrolled growth. While some of the important regulatory networks involved in pancreatic cancer have been determined, the cancer relevant genes have not been fully identified.Methods:We screened genes that may control proliferation in pancreatic cancer in seven pairs of matched pancreatic cancer...

Evaluating the pathogenic potential of genes with de novo variants in epileptic encephalopathies

Epileptic encephalopathies comprise a group of catastrophic epilepsies with heterogeneous genetic etiology. Although next-generation sequencing techniques can reveal a number of de novo variants in epileptic encephalopathies, evaluating the pathogenicity of these variants can be challenging. Determining the pathogenic potential of genes in epileptic encephalopathies is critical...

Atomically thin noble metal dichalcogenide: a broadband mid-infrared semiconductor

• PubMed • Google Scholar Search for Zheng Liu in:Nature Research journals • PubMed • Google Scholar Search for Qi Jie Wang in:Nature Research journals • PubMed • Google Scholar Contributions X.Y. and ... . Competing interests The authors declare no competing interests. Corresponding authors Correspondence to Zheng Liu or Qi Jie Wang. Electronic supplementary material Supplementary Information Rights and

Primary phonological planning units in spoken word production are language-specific: Evidence from an ERP study

It is widely acknowledged in Germanic languages that segments are the primary planning units at the phonological encoding stage of spoken word production. Mixed results, however, have been found in Chinese, and it is still unclear what roles syllables and segments play in planning Chinese spoken word production. In the current study, participants were asked to first prepare and...

Multiferroic Phases and Transitions in Ferroelectric Lead Titanate Nanodots

Discovery of novel phases and their associated transitions in low-dimensional nanoscale systems is of central interest as the origin of emergent phenomena and new device paradigms. Although typical ferroelectrics such as PbTiO3 exhibit diverse phase transition sequences, the conventional incompatible mechanisms of ferroelectricity and magnetism keep them as simply nonmagnetic...

SHP2 associates with nuclear localization of STAT3: significance in progression and prognosis of colorectal cancer

Tyrosine phosphatase SHP2, encoded by PTPN11, has been implicated in many physiologic and pathologic processes in neoplastic progression. However, controversies are emerging from many studies, indicating SHP2 has a dual role in different types of tumors. We aimed to explore the role of SHP2 in progression and prognosis of colorectal cancer (CRC). SHP2 inhibited CRC cell...

Starvation during pregnancy impairs fetal oogenesis and folliculogenesis in offspring in the mouse

Although it is becoming increasingly evident that maternal starvation during pregnancy can have permanent effects on a range of physiological processes in the offspring, scant information is available about the consequence of such condition for oogenesis and hence for lifetime reproductive success of progeny in mammals. In the present study, we address this topic by starving...

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration

Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15224, USA These authors contributed equally: Jie Wang, Cristina Zibetti. AffiliationsDepartment of Ophthalmology, Johns Hopkins ... of Medicine, Baltimore, MD, 21205, USASeth BlackshawInstitute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USASeth Blackshaw AuthorsSearch for Jie Wang

Sliding of coherent twin boundaries

Jiaotong University, Xi’an, 710049, ChinaZhang-Jie Wang, Yao Li, Long-Chao Huang, Ming Dao, Ju Li, Evan Ma & Zhi-Wei ShanDepartment of Materials Science and Engineering, Johns Hopkins University, Baltimore ... , 02139, USAJu LiNanyang Technological University, 50 Nanyang Avenue, Main Campus, Singapore, 639798, SingaporeSubra Suresh AuthorsSearch for Zhang-Jie Wang in:Nature Research journals • PubMed • Google

TRAF6 is a novel NS3-interacting protein that inhibits classical swine fever virus replication

Classical swine fever virus (CSFV) non-structural protein 3 (NS3) is a multifunctional non-structural protein that plays a major role in viral replication. However, how exactly NS3 exerts these functions remains unknown. Here, we identified tumour necrosis factor receptor-associated factor 6 (TRAF6) as a novel NS3-interacting protein via yeast two-hybrid analysis, co...

Integrated omics dissection of proteome dynamics during cardiac remodeling

Transcript abundance and protein abundance show modest correlation in many biological models, but how this impacts disease signature discovery in omics experiments is rarely explored. Here we report an integrated omics approach, incorporating measurements of transcript abundance, protein abundance, and protein turnover to map the landscape of proteome remodeling in a mouse model...

Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats

Lunguo Xia Qianju Wu Jie Wang Xiao Wang Lianyi Xu Yuning Zhou Yuanjin Xu Xinquan Jiang OPEN Typically, bone regenerative medicine is applied to repair bone defects in patients with osteoporosis ... experiments of microfil perfusion and serum detection in Figures 7?8; Qianju Wu and Jie Wang did the rats experiments, including the ovariectomy, calvarial defect experiments and the administration of icariin

Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells

Melanoma Research Center, The Wistar Institute, Philadelphia, PA, 19104, USAMeenhard Herlyn & Ying-Jie Wang AuthorsSearch for Yanwen Zhou in:Nature Research journals • PubMed • Google Scholar Search for ... Research journals • PubMed • Google Scholar Search for Ying-Jie Wang in:Nature Research journals • PubMed • Google Scholar Conflict of interest The authors declare that they have no conflict of interest

Prognostic values of red blood cell distribution width, platelet count, and red cell distribution width-to-platelet ratio for severe burn injury

Guo April Peszel Sheng Liu Fei Wang Ye-Xiang Sun Yong-Jie Wang Xu-Lin Chen OPEN Published: xx xx xxxx Red blood cell distribution width (RDW), platelet count (PLT), and a RDW-to-PLT ratio (RPR) have

Temporal consistency between gross primary production and solar-induced chlorophyll fluorescence in the ten most populous megacity areas over years

The gross primary production (GPP) of vegetation in urban areas plays an important role in the study of urban ecology. It is difficult however, to accurately estimate GPP in urban areas, mostly due to the complexity of impervious land surfaces, buildings, vegetation, and management. Recently, we used the Vegetation Photosynthesis Model (VPM), climate data, and satellite images to...