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41 papers found.
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Astrocytoma progression scoring system based on the WHO 2016 criteria

Diffuse astrocytoma (including glioblastoma) is morbid with a worse prognosis than other types of glioma. Therefore, we sought to build a progression-associated score to improve malignancy and prognostic predictions for astrocytoma. The astrocytoma progression (AP) score was constructed through bioinformatics analyses of the training cohort (TCGA RNA-seq) and included 18 genes...

Giant magnetoelectric effect at the graphone/ferroelectric interface

SIOX. Author information Author notes Jie Wang and Yajun Zhang contributed equally. AffiliationsDepartment of Engineering Mechanics & Key Laboratory of Soft Machines and Smart Devices of Zhejiang ... Shanghai Materials Genome Institute, Shanghai University, 99 Shangda Road, Shanghai, 200444, ChinaTong-Yi Zhang AuthorsSearch for Jie Wang in:Nature Research journals • PubMed • Google Scholar Search for

Macular assessment of preoperative optical coherence tomography in ageing Chinese undergoing routine cataract surgery

This retrospective consecutive case series aimed to evaluate spectral-domain optical coherence tomography (SD-OCT) for occult macular disease recognition preoperatively in patients scheduled for routine cataract surgery. All patients scheduled for cataract surgery underwent macular SD-OCT. Scans were reviewed for retinal, retinal pigment epithelium and vitreomacular interface...

Fault-Tolerant Control of ANPC Three-Level Inverter Based on Order-Reduction Optimal Control Strategy under Multi-Device Open-Circuit Fault

; Chun-Jie Wang Carried out the experiment; Fang-Li Lin dealt with the experiment waveforms; Shi-Xiang Li made the article typesetting. Additional Information Competing Interests: The authors declare

Primary phonological planning units in spoken word production are language-specific: Evidence from an ERP study

It is widely acknowledged in Germanic languages that segments are the primary planning units at the phonological encoding stage of spoken word production. Mixed results, however, have been found in Chinese, and it is still unclear what roles syllables and segments play in planning Chinese spoken word production. In the current study, participants were asked to first prepare and...

Multiferroic Phases and Transitions in Ferroelectric Lead Titanate Nanodots

Discovery of novel phases and their associated transitions in low-dimensional nanoscale systems is of central interest as the origin of emergent phenomena and new device paradigms. Although typical ferroelectrics such as PbTiO3 exhibit diverse phase transition sequences, the conventional incompatible mechanisms of ferroelectricity and magnetism keep them as simply nonmagnetic...

SHP2 associates with nuclear localization of STAT3: significance in progression and prognosis of colorectal cancer

Tyrosine phosphatase SHP2, encoded by PTPN11, has been implicated in many physiologic and pathologic processes in neoplastic progression. However, controversies are emerging from many studies, indicating SHP2 has a dual role in different types of tumors. We aimed to explore the role of SHP2 in progression and prognosis of colorectal cancer (CRC). SHP2 inhibited CRC cell...

TRAF6 is a novel NS3-interacting protein that inhibits classical swine fever virus replication

Classical swine fever virus (CSFV) non-structural protein 3 (NS3) is a multifunctional non-structural protein that plays a major role in viral replication. However, how exactly NS3 exerts these functions remains unknown. Here, we identified tumour necrosis factor receptor-associated factor 6 (TRAF6) as a novel NS3-interacting protein via yeast two-hybrid analysis, co...

Evaluation of Osteogenesis and Angiogenesis of Icariin in Local Controlled Release and Systemic Delivery for Calvarial Defect in Ovariectomized Rats

Lunguo Xia Qianju Wu Jie Wang Xiao Wang Lianyi Xu Yuning Zhou Yuanjin Xu Xinquan Jiang OPEN Typically, bone regenerative medicine is applied to repair bone defects in patients with osteoporosis ... experiments of microfil perfusion and serum detection in Figures 7?8; Qianju Wu and Jie Wang did the rats experiments, including the ovariectomy, calvarial defect experiments and the administration of icariin

Prognostic values of red blood cell distribution width, platelet count, and red cell distribution width-to-platelet ratio for severe burn injury

Guo April Peszel Sheng Liu Fei Wang Ye-Xiang Sun Yong-Jie Wang Xu-Lin Chen OPEN Published: xx xx xxxx Red blood cell distribution width (RDW), platelet count (PLT), and a RDW-to-PLT ratio (RPR) have

Temporal consistency between gross primary production and solar-induced chlorophyll fluorescence in the ten most populous megacity areas over years

The gross primary production (GPP) of vegetation in urban areas plays an important role in the study of urban ecology. It is difficult however, to accurately estimate GPP in urban areas, mostly due to the complexity of impervious land surfaces, buildings, vegetation, and management. Recently, we used the Vegetation Photosynthesis Model (VPM), climate data, and satellite images to...

Polar Superhelices in Ferroelectric Chiral Nanosprings

• PubMed • Google ScholarSearch for Jian-Shan Wang in:Nature Research journals • PubMed • Google ScholarSearch for Jie Wang in:Nature Research journals • PubMed • Google ScholarSearch for Takayuki Kitamura

Genetic variants in interferon-λ 4 influences HCV clearance in Chinese Han population

Recent many studies indicated a novel dinucleotide variant in ss469415590 (TT vs. ΔG) of interferon-λ 4 (IFNL4) gene strongly associated with hepatitis C virus clearance. To evaluate the impact and clinical usefulness of IFNL4 ss469415590 genotype on predicting both spontaneous HCV clearance and response to therapy in Chinese population, we genotyped 795 chronic HCV carriers, 460...

Giant electrocaloric effect in ferroelectric nanotubes near room temperature

AffiliationsDepartment of Engineering Mechanics, School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027, ChinaMan Liu & Jie Wang AuthorsSearch for Man Liu in:Nature Research journals • PubMed ... • Google ScholarSearch for Jie Wang in:Nature Research journals • PubMed • Google Scholar Contributions J.W. conceived and designed the concept. M.L. conducted the simulations. M.L. and J.W. wrote the paper

Effects of exercise-based cardiac rehabilitation in patients after percutaneous coronary intervention: A meta-analysis of randomized controlled trials

(JDZX2015007). Author information AffiliationsGuang’anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, ChinaXinyu Yang, Yanda Li, Xingjiang Xiong, Jie Li, Jie Wang & Yanwei XingThe ... • PubMed • Google ScholarSearch for Lijun Wu in:Nature Research journals • PubMed • Google ScholarSearch for Jie Li in:Nature Research journals • PubMed • Google ScholarSearch for Jie Wang in:Nature Research

CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice

Qi and Zhenzhen Zeng carried out the in vitro and animal experiments. Jie Wang, Ting Zhang, Qiang Xu and Congle Shen carried out the vector design. Lu Wang, Guangde Zhou and Shaomin Yang offered

Integrative analysis of copy number and transcriptional expression profiles in esophageal cancer to identify a novel driver gene for therapy

An increasing amount of evidence has highlighted the critical roles that copy number variants play in cancer progression. Here, we systematically analyzed the copy number alterations and differentially transcribed genes. Integrative analysis of the association between copy number variants and differential gene expression suggested that copy number variants will lead to aberrant...

Use of recombinant porcine β-defensin 2 as a medicated feed additive for weaned piglets

Post-weaning diarrhoea (PWD) in piglets is associated with colonization of the intestine with bacterial pathogens. In this study, we evaluated the use of recombinant porcine β-defensin 2 (rpBD2) as a medicated feed additive for weaned piglets. The crude extract from the culture supernatant of rpBD2-expressing Pichia pastoris was used as a medicated feed additive for weaned...

Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain

The ventrobasal (VB) thalamus is innervated by GABAergic afferents from the thalamic reticular nucleus (TRN) and participates in nociception. But how the TRN-VB pathway regulates pain is not fully understood. In the present study, we reported decreased extracellular GABA levels in the VB of rats with CFA-induced chronic inflammatory pain, measured by microdialysis with HPLC...