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3D Modeling and Visualization of Geology Volume based on Geophysical Field Data

3D modeling and visualization of geology volume is very important to interpret accurately and locate subsurface geology volume for mining exploration and deep prospecting. However, it faces a lack of information because the target area is usually unexplored and lacks geological data. This paper presents our experience in applying a 3D model of geology volume based on geophysics...

4-Phenylbutyric Acid Induces Protection against Pulmonary Arterial Hypertension in Rats

Background Endoplasmic reticulum (ER) stress has been implicated in the pathophysiology of various pulmonary diseases via the activation of the unfolded protein response. However, the role of ER stress in pulmonary arterial hypertension (PAH) remains unclear. The well-known chemical chaperone 4-phenylbutyric acid (4-PBA) inhibits ER stress signaling. We hypothesized that known...

A Multi-Center Study to Evaluate the Performance of Phage Amplified Biologically Assay for Detecting TB in Sputum in the Pulmonary TB Patients

Objective To evaluate the performance of phage amplified biologically assay (PhaB) for detecting tuberculosis (TB) in sputum in the pulmonary tuberculosis (PTB) patients. Methods Shanghai Tuberculosis Key Laboratory of Shanghai Pulmonary Hospital participated in the project in collaboration with the laboratories of six hospitals and a total of 1660 eligible participants (1351 PTB...

A Novel B-Cell Epitope Identified within Mycobacterium tuberculosis CFP10/ESAT-6 Protein

Background The 10-kDa culture filtrate protein (CFP10) and 6-kDa early-secreted target antigen (ESAT-6) play important roles in mycobacterial virulence and pathogenesis through a 1∶1 complex formation (CFP10/ESAT-6 protein, CE protein), which have been used in discriminating TB patients from BCG-vaccinated individuals. The B-cell epitopes of CFP10 and ESAT-6 separately have been...

A Novel Inflammation-Based Prognostic Score: The Fibrinogen/Albumin Ratio Predicts Prognoses of Patients after Curative Resection for Hepatocellular Carcinoma

Songgang Gu,3 Kai Mao,1,2 Jianlong Zhang,1,2 Pinbo Huang,1,2 Zhenyu Zhou,1,2 Zheng Chen,1,2 Shaodong Zheng,3 Jiahong Liang,3 Zhihua Lin,3 Jie Wang,1,2 Jiang Yan,3 and Zhiyu Xiao1,2 1Guangdong Province Key ... Medical College, No. 57 Changping Road, Shantou 515041, China Correspondence should be addressed to Jie Wang; moc.361@usysweij, Jiang Yan; moc.anis@gnaijnayts, and Zhiyu Xiao; moc.361@noegrusyzx Received

A Novel Multiple Instance Learning Method Based on Extreme Learning Machine

450001, China Received 18 December 2014; Revised 18 January 2015; Accepted 18 January 2015 Academic Editor: Thomas DeMarse Copyright © 2015 Jie Wang et al. This is an open access article distributed

A Numerical Study on the Performance of Nonlinear Models of a Microvibration Isolator

Aeronautics and Astronautics, Beijing 100191, China Received 26 February 2014; Accepted 27 May 2014; Published 22 July 2014 Academic Editor: Chao Tao Copyright © 2014 Jie Wang et al. This is an open access

A Numerical Study on the Performance of Nonlinear Models of a Microvibration Isolator

Aeronautics and Astronautics, Beijing 100191, China Received 26 February 2014; Accepted 27 May 2014; Published 22 July 2014 Academic Editor: Chao Tao Copyright © 2014 Jie Wang et al. This is an open access

A Pilot Study of the Therapeutic Efficacy and Mechanism of Artesunate in the MRL/lpr Murine Model of Systemic Lupus Erythematosus

Recent evidence indicates that artesunate has immunomodulatory properties that might be useful for treating autoimmune disease. In this study, we conducted a pilot study and explored the effect and mechanism of artesunate on the treatment of systemic lupus erythematosus using an MRL/lpr murine model. MRL/lpr mice were divided into control, cyclophosphamide (CTX) and artesunate...

A Reference Proteomic Database of Lactobacillus plantarum CMCC-P0002

Lactobacillus plantarum is a widespread probiotic bacteria found in many fermented food products. In this study, the whole-cell proteins and secretory proteins of L. plantarum were separated by two-dimensional electrophoresis method. A total of 434 proteins were identified by tandem mass spectrometry, including a plasmid-encoded hypothetical protein pLP9000_05. The information of...

A Vessel Positioning Algorithm Based on Satellite Automatic Identification System

Vessels can obtain high precision positioning by using the global navigation satellite system (GNSS), but when the ship borne GNSS receiver fails, the existence of an alternative positioning system is important for the navigation safety of vessel. In this paper, a localization method based on the signals transmitted by satellite-based automatic identification system (AIS) is...

A case report of spontaneous rupture of intracranial epidermoid cyst with dramatic increase of serum carbohydrate antigen 199: a three-year follow-up study

Background Tumor markers are widely applied in clinical practice, however, few serum markers have been found for intracranial tumors. Herein, we firstly report an intracranial epidermoid cyst case with extremely high level of serum CA 199. Furthermore, the relationship between CA 199 level and intracranial epidermoid cyst was closely followed for a long period. Case presentation...

A cross-sectional study of HIV and syphilis infections among male students who have sex with men (MSM) in northeast China: implications for implementing HIV screening and intervention programs

Background China has 76.2 million high school and college students, in which the number of reported HIV/AIDS cases is increasing rapidly. Most of these cases are attributed to male-to-male sexual contact. Few studies have explored HIV prevalence and behavioural characteristics of Chinese male students who have sex with men (MSM). Methods A cross-sectional study of MSM high school...

A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response

The Replication Stress Response (RSR) is a signaling network that recognizes challenges to DNA replication and coordinates diverse DNA repair and cell-cycle checkpoint pathways. Gemcitabine is a nucleoside analogue that causes cytotoxicity by inducing DNA replication blocks. Using a synthetic lethal screen of a RNAi library of nuclear enzymes to identify genes that when silenced...

A meta-analysis of data associating DRD4 gene polymorphisms with schizophrenia

A meta-analysis of data associating DRD4 gene polymorphisms with schizophrenia Feng-ling Xu, Xue Wu, Jing-jing Zhang, Bao-jie Wang, Jun Yao Department of Forensic, Genetic and Biology Medicine

A note on fractional integral operators on Herz spaces with variable exponent

In this note, we prove that the fractional integral operators from Herz spaces with variable exponent K ˙ p ( ⋅ ) , q α to Lipschitz-type spaces are bounded provided p ( ⋅ ) is locally log-Hölder continuous and log-Hölder continuous at infinity. MSC: 42B20, 46E30.

A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway

PANG, Hong LIAO, Lu-yong ZHANG, Jian-rong GAO, Qing YE, and Jia LI designed the research; Tao PANG, Yun-jie WANG, Yuan-xue GAO, Yuan XU, Yu-bo ZHOU, and Lei XU performed the research; Qiu LI and Qing

A novel anti-virulence gene revealed by proteomic analysis in Shigella flexneri 2a

Background Shigella flexneri is a gram-negative, facultative pathogen that causes the majority of communicable bacterial dysenteries in developing countries. The virulence factors of S. flexneri have been shown to be produced at 37 degrees C but not at 30 degrees C. To discover potential, novel virulence-related proteins of S. flexneri, we performed differential in-gel...