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A case of an infant suspected as IMAGE syndrome who were finally diagnosed with MIRAGE syndrome by targeted Mendelian exome sequencing

Adrenal hypoplasia is a rare congenital disorder, which can be classified into a non-syndromic form, without extra-adrenal features, and a syndromic form, with such features. Despite biochemical and molecular genetic evaluation, etiologic diagnosis cannot be performed in many patients with adrenal hypoplasia. The patient in this case was a boy born at 31 weeks of gestation with a...

Body mass index and weight change during initial period of chemotherapy affect survival outcome in advanced biliary tract cancer patients

curation: Jinwoo Kang, Jae Woo Lee, Young Hoon Choi, Jin Ho Choi. Investigation: Jinwoo Kang. Methodology: Jinwoo Kang, Sang Hyub Lee. Supervision: Ji Kon Ryu, Yong-Tae Kim. Writing ± original draft

Non-invasive coronary physiology based on computational analysis of intracoronary transluminal attenuation gradient

Invasive procedure is a prerequisite for studying coronary physiology. We established the measurement of non-invasive physiological parameters including coronary blood flow (CBF), flow velocity, and microvascular resistance using coronary computed tomography angiography (CCTA). Vessel-specific CBF was derived from transluminal attenuation flow encoding (TAFE) and then tested...

Nature of the Insulating Ground State of the Two-Dimensional Sn Atom Lattice on SiC(0001)

Physics and Research Institute for National Sciences, Hanyang University, 17 Haengdang-Dong, Seongdong-Ku, Seoul 133-791, KoreaSeho Yi, Jin-Ho Choi & Jun-Hyung ChoSchool of General Studies, Kangwon National ... AuthorsSearch for Seho Yi in:Nature Research journals • PubMed • Google ScholarSearch for Hunpyo Lee in:Nature Research journals • PubMed • Google ScholarSearch for Jin-Ho Choi in:Nature Research journals

Duration of dual antiplatelet therapy in patients treated with percutaneous coronary intervention for coronary chronic total occlusion

Background The duration of dual antiplatelet therapy (DAPT) after drug-eluting stent implantation in coronary chronic total occlusion (CTO) remains unclear. Methods We retrospectively analyzed a total of 512 patients treated with percutaneous coronary intervention (PCI) in the Samsung Medical Center CTO registry. Patients were separated into ≤ 12-month (199, 38.9%) vs. > 12 month...

The association of findings on brain computed tomography with neurologic outcomes following extracorporeal cardiopulmonary resuscitation

Background Limited data are available on imaging predictors of neurological outcomes after extracorporeal cardiopulmonary resuscitation (ECPR). We investigated the association of initial brain computed tomography (CT) findings with neurological outcomes following ECPR. Methods Between February 2005 and December 2015, a total of 42 patients who underwent brain CT scans within 48 h...

Coronary angiography is related to improved clinical outcome of out-of-hospital cardiac arrest with initial non-shockable rhythm

-shockable OHCA. Acknowledgments Drs. Jin-Ho Choi, Won Chul Cha, and Sang Do Shin are member of Cardiac Arrest Pursuit Trial with Unique Registry and Epidemiologic Surveillance investigators This study was ... : Eunsil Ko. Data curation: Eunsil Ko, Ji Kyoung Shin, Tae Rim Lee, Guntak Lee. Formal analysis: Tae Rim Lee, Guntak Lee, Jin-Ho Choi. Funding acquisition: Sang Do Shin. Investigation: Eunsil Ko, Won

Clinical outcomes of biodegradable polymer biolimus-eluting BioMatrix stents versus durable polymer everolimus-eluting Xience stents

: Young Bin Song, Woo Jung Chun, Rak Kyeong Choi, Jin-Ok Jeong, Eul Soon Im, Sang Wook Kim, Joo Myung Lee, Jeong Hoon Yang, Joo-Yong Hahn, Seung-Hyuk Choi, Jin-Ho Choi, Sang Hoon Lee, Hyeon-Cheol Gwon ... Im, Sang Wook Kim, Joo Myung Lee, Jeong Hoon Yang, Joo-Yong Hahn, Seung-Hyuk Choi, Jin-Ho Choi, Sang Hoon Lee, Hyeon-Cheol Gwon. Methodology: Young Bin Song, Jeong Hoon Yang, Joo-Yong Hahn, Hyeon

Impaired osteogenesis in Menkes disease-derived induced pluripotent stem cells

Introduction Bone abnormalities, one of the primary manifestations of Menkes disease (MD), include a weakened bone matrix and low mineral density. However, the molecular and cellular mechanisms underlying these bone defects are poorly understood. Methods We present in vitro modeling for impaired osteogenesis in MD using human induced pluripotent stem cells (iPSCs) with a mutated...

The association of findings on brain computed tomography with neurologic outcomes following extracorporeal cardiopulmonary resuscitation

Limited data are available on imaging predictors of neurological outcomes after extracorporeal cardiopulmonary resuscitation (ECPR). We investigated the association of initial brain computed tomography (CT) findings with neurological outcomes following ECPR. Between February 2005 and December 2015, a total of 42 patients who underwent brain CT scans within 48 h after ECPR were...

Impaired osteogenesis in Menkes disease-derived induced pluripotent stem cells

Bone abnormalities, one of the primary manifestations of Menkes disease (MD), include a weakened bone matrix and low mineral density. However, the molecular and cellular mechanisms underlying these bone defects are poorly understood. We present in vitro modeling for impaired osteogenesis in MD using human induced pluripotent stem cells (iPSCs) with a mutated ATP7A gene. MD-iPSC...

Morphine Does Not Affect Myocardial Salvage in ST-Segment Elevation Myocardial Infarction

Recent studies have proposed intravenous (IV) morphine is associated with delayed action of antiplatelet agents in acute myocardial infarction. However, it is unknown whether morphine results in increased myocardial damage in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI). We investigated myocardial salvage...

The Impact of Renal Dysfunction on the Long Term Clinical Outcomes of Diabetic Patients Undergoing Percutaneous Coronary Intervention in the Drug-Eluting Stent Era

Background Limited data are available regarding the association between renal dysfunction and clinical outcomes in diabetic patients undergoing percutaneous coronary intervention (PCI) in the drug-eluting stent (DES) era. Methods Between March 2003 and December 2010, 2,181 diabetic patients were enrolled in a single-center registry. We divided diabetic patients into a renal...

Predictors of neurological outcomes after successful extracorporeal cardiopulmonary resuscitation

Yang Jin-Ho Choi Dae-Sang Lee Ji-Hyuk Yang 0 0 Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul , South Korea Background