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Study on expression of plasma sCD138 in patients with hemorrhagic fever with renal syndrome

Until now, there is non-specific treatment, and exploring early and novel biomarkers to determine the disease severity and prognosis of hemorrhagic fever with renal syndrome (HFRS) would be of importance for clinician to take systematic and timely intervention. This study observed the expression of plasma sCD138, a soluble component shedding from the glycocalyx (GCX) to the...

Prevalence and associated knowledge of hepatitis B infection among healthcare workers in Freetown, Sierra Leone

Sun, Jing Li, Zhong-Peng Zhao, Jun Jiao, Ya-Jun Song, Tian-Jun Jiang, Jia-Fu Jiang. Funding This project was supported by a training grant by Beijing 302 Hospital, of which YLQ and JFJ were

Antimicrobial resistance in Neisseria gonorrhoeae in China: a meta-analysis

Background Neisseria gonorrhoeae (N. gonorrhoeae) resistance to antimicrobial has been a major concern in China, and epidemiological data on N. gonorrhoeae resistance are not well understood. This meta-analysis was aimed at summarizing the evidence on N. gonorrhoeae resistance to penicillin, tetracycline, ciprofloxacin, ceftriaxone and spectinomycin in China. Methods Two...

Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experiment

Background China-made Peramivir, an anti-influenza neuraminidase inhibitor drug, is manufactured and widely used in China. Although effective if initiated within 48 h of the onset of symptoms, yet we observed that this drug shows an inconclusive efficacy if treatment is delayed in clinical. Thus we evaluated the efficacy of delayed treatment of China-made Peramivir in a mouse...

Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experiment

experience to basal experiment Zhengtu Li†1, Runfeng Li†1, Jing Li†1, Hui Xie†1, Yanbing Hao1, Qiuling Du1, Tingting Chen1, Yimin Li1, Rongchang Chen1Email author, Zifeng Yang1, 2Email author and Nanshan

Persistently high prevalence of primary resistance and multidrug resistance of tuberculosis in Heilongjiang Province, China

Background The spread of multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M. tuberculosis) strains has been a big challenge to the TB control and prevention in China. Knowledge about patterns of drug resistance in TB high-burden areas of China is crucial to develop appropriate control strategies. We conducted a comprehensive investigation of the resistance...

A case–control study of risk factors for HIV-negative children with cryptococcal meningitis in Shi Jiazhuang, China

Jing Li Yinqi Sun Shunxiang Qi 0 Shi Jiazhuang Center for Disease Prevention and Control (CDC) , Shi Jiazhuang 050011 , People's Republic of China 1 Institute for Epidemiology and Health Emergency, Shi

Clinical characteristics and outcomes in critical patients with hemorrhagic fever with renal syndrome

Background Hemorrhagic fever with renal syndrome (HFRS) has become an important public health concern because of the high incidence and mortality rates, and limited treatment and vaccination. Until now, clinical studies on characteristics and outcomes in critical patients with HFRS have been limited. The aim of this study was to observe the clinical characteristics and cumulative...

A prospective study of age trends of high-risk human papillomavirus infection in rural China

Background In China, high-risk human papillomavirus (HR-HPV) prevalence is unexpectedly high in older women, but the possible reasons have not been well studied yet. This study investigated the age trends of HR-HPV infection in a prospective study. Methods A total of 7397 women aged 25-65 years without cervical precancer or cancer were evaluated during 2010-2011 with a stratified...

A prospective study of age trends of high-risk human papillomavirus infection in rural China

In China, high-risk human papillomavirus (HR-HPV) prevalence is unexpectedly high in older women, but the possible reasons have not been well studied yet. This study investigated the age trends of HR-HPV infection in a prospective study. A total of 7397 women aged 25-65 years without cervical precancer or cancer were evaluated during 2010-2011 with a stratified sample of 2791...