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Highly Sensitive and Stable SERS Substrate Fabricated by Co-sputtering and Atomic Layer Deposition

In this study, we develop a facile method to fabricate highly sensitive and stable surface-enhanced Raman scattering (SERS) substrate, which is realized by combining co-sputtering with atomic layer deposition technology. To accomplish the SERS substrate preparation, we firstly utilized co-sputtering silver and aluminum on glass slides to form uniform discontinuous Ag film by...

ZrB2 particles reinforced glass coating for oxidation protection of carbon/carbon composites

A dense ZrB2 particles reinforced glass (ZrB2/SiO2) coating was prepared on the SiC coated carbon/carbon composites by a facile sol-dipping approach. The prepared ZrB2/SiO2 coating could protect the composites from being oxidized for 160 h at 1773 K with a weight loss of 6.9 mg/cm2. The flexural strength retention ratio of the ZrB2/SiO2 coated composites is 87% after oxidation...

HIV-1 genotype diversity and distribution characteristics among heterosexually transmitted population in Jiangsu province, China

Heterosexual transmission has contributed greatly to the current HIV-1 epidemic in China. However, the HIV-1 genetic characteristics in the heterosexually transmitted population in Jiangsu province remained unclear. A molecular epidemiological investigation on heterosexual transmission of HIV-1 was conducted across Jiangsu province. 301 HIV-1 patients infected through...

Efficacy and Safety of Basal Analog Regimens in Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomized Controlled Trials

. Funding Sanofi (Shanghai, China). KeywordsBasal-bolus insulin therapy Basal insulin analogues Meta-analysis Premix insulin therapy Systematic review Type 2 diabetes mellitus  Ting Hong and Jing Lu ... reports employment by Doctor Evidence, who was contracted to produce the analysis. Ting Hong, Jing Lu, Pengzi Zhang, Zhou Zhang, Qianyue Xu, and Bi Yan have nothing to disclose. Compliance with Ethics

Seed tissue and nutrient partitioning, a case for the nucellus

Flowering plants display a large spectrum of seed architectures. The volume ratio of maternal versus zygotic seed tissues changes considerably among species and underlies different nutrient-storing strategies. Such diversity arose through the evolution of cell elimination programs that regulate the relative growth of one tissue over another to become the major storage compartment...

Correction to: Immunogenicity of adenovirus-vector vaccine targeting hepatitis B virus: non-clinical safety assessment in non-human primates

Ad-HBV is a product (T101) aiming to treat chronic HBV firstly developed by Transgene S.A., France then by Transgene Tasly (Tianjin) Biopharmaceutical Co., Ltd., Tianjin, China in China.

New Dammarane Triterpenoids, Caffruones A–D, from the Cherries of Coffea arabica

In present study, four new dammarane-type triterpenoids, namely caffruones A–D (1–4), were isolated from the cherries of Coffea arabica. Their structures were elucidated by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, 1H–1H COSY, and ROESY), HRMS and IR spectra. This is the first time that tetracyclic triterpenes have been reported in genus Coffea.Graphical...

Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease

-Qiong Wu†1, Di Sun1, Hui-Hui Liu1, Jing-Lu Jin1, Sha Li1, Yuan-Lin Guo1, Cheng-Gang Zhu1, Ying Gao1, Qiu-Ting Dong1, Geng Liu1, Qian Dong1 and Jian-Jun Li1Email authorView ORCID ID profile †Contributed

Effects of Intestinal Microbiota on Brain Development in Humanized Gnotobiotic Mice

Poor growth in the Neonatal Intensive Care Unit is associated with an increased risk for poor neurodevelopmental outcomes for preterm infants, however the mechanism is unclear. The microbiome has increasingly been recognized as a modifiable environmental factor to influence host development. Here we explore the hypothesis that the microbiome influences both growth phenotype and...

Microbiota influence the development of the brain and behaviors in C57BL/6J mice

font indicates if p-values<0.05. The value in parenthesis indicated p-values, corrected for multiple comparisons using False Discovery Rate (q = 0.05). (PDF) Conceptualization: Jing Lu, Michael Caplan ... , Erika C. Claud, Alexander Drobyshevsky. Data curation: Jing Lu, Sylvia Synowiec, Lei Lu, Yueyue Yu, Talitha Bretherick, Silvia Takada, Vasily Yarnykh, Jack Caplan, Michael Caplan, Alexander Drobyshevsky

New findings in a 400 million-year-old Devonian placoderm shed light on jaw structure and function in basal gnathostomes

Arthodire placoderms have been proposed as the sister group of Chinese ‘maxillate’ placoderms plus all the more crownward gnathostomes. These basal groups provide key information for understanding the early evolution of jaws. Here, we test previous assumptions about placoderm jaw structure and function by using high-resolution computed tomography, digital dissection, and enlarged...

Elevated Serum Interleukin-34 Level in Patients with Systemic Lupus Erythematosus Is Associated with Disease Activity

We measured the interleukin-34 (IL-34) level in sera from patients with systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE) using an enzyme-linked immunosorbent assay (ELISA). Blood tests, including assays to determine C-reactive protein (CRP), complement (C) 3, C4, immunoglobulin (Ig) A, IgG, IgM, anti-double-stranded DNA antibody (Anti-dsDNA Ab) and...

A computational method for the identification of candidate drugs for non-small cell lung cancer

EM algorithm on 98 candidate compounds and ten approved NSCLC drugs. (DOCX) Author Contributions Conceptualization: Lei Chen, Yu-Dong Cai. Data curation: Lei Chen. 12 / 15 Formal analysis: Jing Lu ... , Tao Huang. Funding acquisition: Lei Chen, Yu-Dong Cai. Methodology: Lei Chen, Jing Lu. Supervision: Yu-Dong Cai. Validation: Jing Lu, Tao Huang, Yu-Dong Cai. Writing ± original draft: Lei Chen, Jing

Cooperative Dynamic Manipulation of Unknown Flexible Objects

systems. Jing Lu received the Bachelor Degree in Control Engineering from University of Kaiserslautern, Germany and from Fuzhou University, China in 2014. She received the Master Degree in Automatic

Volatility Spillovers in Capesize Forward Freight Agreement Markets

Innovation Center for Transport Studies, Dalian Maritime University, Dalian 116026, China Received 3 July 2016; Accepted 9 October 2016 Academic Editor: Xiaofeng Xu Copyright © 2016 Xiaoxing Gong and Jing ... Lu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work

Volatility Spillovers in Capesize Forward Freight Agreement Markets

Innovation Center for Transport Studies, Dalian Maritime University, Dalian 116026, China Received 3 July 2016; Accepted 9 October 2016 Academic Editor: Xiaofeng Xu Copyright © 2016 Xiaoxing Gong and Jing ... Lu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work

ETV2 mediates endothelial transdifferentiation of glioblastoma

, Gustavo A. Gomez, Jing Lu & Shuo LinBlood Research Laboratory, Chengdu Blood Center, Sichuan, ChinaYuwei ZhaoState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University ... • Google Scholar Search for Dan Cao in:Nature Research journals • PubMed • Google Scholar Search for Jing Lu in:Nature Research journals • PubMed • Google Scholar Search for Hanshuo Yang in:Nature Research

Differential expression of genes identified by suppression subtractive hybridization in liver and adipose tissue of gerbils with diabetes

. Methodology: Jingjing Gong, Zhenkun Li, Xiaohong Li, Meng Guo, Jing Lu, Ying Wang. Project administration: Xiaohong Li. Resources: Meng Guo, Jing Lu, Ying Wang, Zhenwen Chen, Changlong Li. Software: Jingjing

Link prediction in author collaboration network based on BP neural network

Recently, more and more authors have been encouraged for collaboration because it often produces good results. However, the author collaboration network contains experts in various research directions within various fields, and it is difficult for individual authors to decide which authors are best suited to their expertise. This paper uses the relationships among authors to...