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Apigenin Attenuates Atherogenesis through Inducing Macrophage Apoptosis via Inhibition of AKT Ser473 Phosphorylation and Downregulation of Plasminogen Activator Inhibitor-2

Macrophage survival is believed to be a contributing factor in the development of early atherosclerotic lesions. Dysregulated apoptosis of macrophages is involved in the inflammatory process of atherogenesis. Apigenin is a flavonoid that possesses various clinically relevant properties such as anti-inflammatory, antiplatelet, and antitumor activities. Here we showed that apigenin...

Apigenin Attenuates Atherogenesis through Inducing Macrophage Apoptosis via Inhibition of AKT Ser473 Phosphorylation and Downregulation of Plasminogen Activator Inhibitor-2

Wang,3 Qin Fan,3 Jian-Xin Diao,3 Jing Tang,4 Xiu-Qiong Fu,3,5 and Xue-Gang Sun3,4 1Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China 2Guangzhou Institute of

PRAK Interacts with DJ-1 and Prevents Oxidative Stress-Induced Cell Death

; Accepted 27 August 2014; Published 14 October 2014 Academic Editor: Ozcan Erel Copyright © 2014 Jing Tang et al. This is an open access article distributed under the Creative Commons Attribution License

PRAK Interacts with DJ-1 and Prevents Oxidative Stress-Induced Cell Death

; Accepted 27 August 2014; Published 14 October 2014 Academic Editor: Ozcan Erel Copyright © 2014 Jing Tang et al. This is an open access article distributed under the Creative Commons Attribution License

Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes

Shenzhen Hospital, Shenzhen, Guangdong 518053, China Received 18 April 2014; Accepted 16 July 2014; Published 11 August 2014 Academic Editor: Neelam Khaper Copyright © 2014 Jing Tang et al. This is an ... this study. Authors’ Contribution Jing Tang and Ji-Jie Hu contributed equally to this work. Acknowledgments This work was supported by the National Natural Science Foundation of China (81301664 and

Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes

Shenzhen Hospital, Shenzhen, Guangdong 518053, China Received 18 April 2014; Accepted 16 July 2014; Published 11 August 2014 Academic Editor: Neelam Khaper Copyright © 2014 Jing Tang et al. This is an ... this study. Authors’ Contribution Jing Tang and Ji-Jie Hu contributed equally to this work. Acknowledgments This work was supported by the National Natural Science Foundation of China (81301664 and