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Interpreting the MicroRNA-15/107 family: interaction identification by combining network based and experiment supported approach

The highly conservative miR-15/107 family (also named as miR-15/107 gene group) including ten miRNA members is currently recognized strongly implicated in multiple human disorders. Some studies focus on the entire family rather than individual miRNA for a bigger picture, while there is also certain signature dysregulation for some of the individual miRNA implicated even in the...

Phase engineering of two-dimensional transition metal dichalcogenides

璐)Jing Xu (徐婧)Lei Fu (付磊) Reviews First Online: 13 February 2019 74 Downloads Abstract Two-dimensional (2D) transition metal dichalcogenides (TMDs) have gained much attention in virtue of

Orbital-flop Induced Magnetoresistance Anisotropy in Rare Earth Monopnictide CeSb

The charge and spin of the electrons in solids have been extensively exploited in electronic devices and in the development of spintronics. Another attribute of electrons—their orbital nature—is attracting growing interest for understanding exotic phenomena and in creating the next-generation of quantum devices such as orbital qubits. Here, we report on orbital-flop induced...

Lnc SMAD5-AS1 as ceRNA inhibit proliferation of diffuse large B cell lymphoma via Wnt/β-catenin pathway by sponging miR-135b-5p to elevate expression of APC

Diffuse large B cell lymphoma (DLBCL) is a common and fatal hematological malignancy. Long noncoding RNAs (lncRNAs) have emerged as crucial biomarkers and regulators in many cancers. Novel lncRNA biomarker in DLBCL needs to be investigated badly, as well as its function and molecular mechanism. To further explore, microarray analysis was performed to identify the differentially...

The interplay between exosomes and autophagy – partners in crime

The eukaryotic endomembrane system is a complex series of interconnected membranous organelles that play important roles in responding to stress and maintaining cell homeostasis during health and disease. Two components of this system, exosome biogenesis and autophagy, are linked by the endolysosomal pathway. Exosomes are cargo-laden extracellular vesicles that arise from...

Correction: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice

Kazuya Matsuo Jing Xu Hisanao Izumi Kenji Sakimura Takashi Saito Takaomi C. Saido Kohji Fukunaga In the Funding section, one of the grant numbers from the funder Scientific Research from the Ministry of

24-nt reproductive phasiRNAs are broadly present in angiosperms

Small RNAs are key regulators in plant growth and development. One subclass, phased siRNAs (phasiRNAs) require a trigger microRNA for their biogenesis. In grasses, two pathways yield abundant phasiRNAs during anther development; miR2275 triggers one class, 24-nt phasiRNAs, coincident with meiosis, while a second class of 21-nt phasiRNAs are present in premeiotic anthers. Here we...

Necroptosis in primate luteolysis: a role for ceramide

& Developmental Sciences, Oregon National Primate Research Center, Oregon Health & Science University, 505 NW 185th Avenue, Beaverton, Oregon, 97006, USACecily Bishop & Jing Xu AuthorsSearch for Konstantin Bagnjuk ... Search for Cecily Bishop in:Nature Research journals • PubMed • Google Scholar Search for Jing Xu in:Nature Research journals • PubMed • Google Scholar Search for Artur Mayerhofer in:Nature Research

Study of CP violations in \(B^-\rightarrow K^- \pi ^+\pi ^-\) and \(B^-\rightarrow K^- f_0(500)\) decays in the QCD factorization approach

Within the QCD factorization approach, we study the CP violations in \(B^-\rightarrow K^-\pi ^+\pi ^-\) and \(B^-\rightarrow K^- f_0(500)\) decays. We find the experimental data of the localized CP asymmetry in \(B^-\rightarrow K^-\pi ^+\pi ^-\) decays in the region \(m_{K^-\pi ^+}^2<15\) \(\mathrm {GeV}^2\) and \(0.08<m_{\pi ^+\pi ^-}^2<0.66\) \(\mathrm {GeV}^2\) can be...

T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice

S1 File. Low data. (XLSX) Author Contributions Investigation: Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi. Methodology: Kenji Sakimura, Takashi Saito, Takaomi C. Saido

Self-Healing of Concrete Cracks by Ceramsite-Loaded Microorganisms

Protective carrier is essential for the self-healing of concrete cracks by microbially induced CaCO3 precipitation, owing to the harsh conditions in concrete. In this paper, porous ceramsite particles are used as microbial carrier. Heat treatment and NaOH soaking are first employed to improve the loading content of the ceramsite. The viability of bacterial spores is assessed by...

Self-Healing of Concrete Cracks by Ceramsite-Loaded Microorganisms

Copyright © 2018 Jing Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture

Sepsis is a systemic inflammatory response syndrome caused by severe infections. LDK378, a second-generation ALK inhibitor, exhibits a potential anti-inflammatory function against sepsis. Micro- and macro-circulatory dysfunctions are pivotal elements of the pathogenesis of severe sepsis and septic shock. We hypothesized that LDK378 can improve micro- and macro-circulation of...

CYT997(Lexibulin) induces apoptosis and autophagy through the activation of mutually reinforced ER stress and ROS in osteosarcoma

Osteosarcoma (OS) is a common malignant cancer in children and adolescents and has a cure rate that has not improved in the last two decades. CYT997 (lexibulin) is a novel potent microtubule-targeting agent with various anticancer activities, such as proliferation inhibition, vascular disruption, and cell cycle arrest and apoptosis induction, in multiple cancers. However, the...

Unsupervised Medical Entity Recognition and Linking in Chinese Online Medical Text

, Changsha, China Correspondence should be addressed to Jing Xu; nc.ude.tdun@ux.gnij Received 28 September 2017; Accepted 2 January 2018; Published 18 April 2018 Academic Editor: Robertas Damaševičius ... Copyright © 2018 Jing Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Unsupervised Medical Entity Recognition and Linking in Chinese Online Medical Text

, Changsha, China Correspondence should be addressed to Jing Xu; nc.ude.tdun@ux.gnij Received 28 September 2017; Accepted 2 January 2018; Published 18 April 2018 Academic Editor: Robertas Damaševičius ... Copyright © 2018 Jing Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Real-time pre-processing system with hardware accelerator for mobile core networks

With the rapidly increasing number of mobile devices being used as essential terminals or platforms for communication, security threats now target the whole telecommunication infrastructure and become increasingly serious. Network probing tools, which are deployed as a bypass device at a mobile core network gateway, can collect and analyze all the traffic for security detection...

miR-1260b, mediated by YY1, activates KIT signaling by targeting SOCS6 to regulate cell proliferation and apoptosis in NSCLC

Nanjing Medical University, Nanjing, 210029, ChinaYang Xia, Ke Wei, Chun-Feng Pan, Xiang-Long Pan, Wei-Bing Wu, Jun Wang, Wei Wen, Zhi-Cheng He, Jing Xu, Xin-Feng Xu, Quan Zhu & Liang ChenDepartment of ... journals • PubMed • Google Scholar Search for Wei Wen in:Nature Research journals • PubMed • Google Scholar Search for Zhi-Cheng He in:Nature Research journals • PubMed • Google Scholar Search for Jing Xu

Acetylcholine and necroptosis are players in follicular development in primates

Acetylcholine (ACh) in the ovary and its actions were linked to survival of human granulosa cells in vitro and improved fertility of rats in vivo. These effects were observed upon experimental blockage of the ACh-degrading enzyme (ACH esterase; ACHE), by Huperzine A. We now studied actions of Huperzine A in a three-dimensional culture of macaque follicles. Because a form of...

Phylogenetic diversity and antioxidant activities of culturable fungal endophytes associated with the mangrove species Rhizophora stylosa and R. mucronata in the South China Sea

Contributions Conceptualization: Jing Xu. Formal analysis: Tao Wang. Funding acquisition: Guangying Chen. Investigation: Jing Zhou. Methodology: Xiaoping Diao. Resources: Qiang Lin. Supervision: Xiaobo ... Yang. Validation: Jing Xu. Writing ? original draft: Jing Xu. Writing ? review & editing: Xiaobo Yang. 16 / 18 11. Xu J. Natural products of mangrove-derived microbes. Beijing. Science Press. ISBN 97