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13 papers found.
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Imbalance in obesity and mental health among “little emperors” in China

in the study. Author Contributions Data curation: Jingjing Liang. Formal analysis: Zhen Wei. Funding acquisition: Ziwen Peng. Investigation: Zhongyan Zheng, Jingjing Liang. Methodology: Jianping

Preventative effects of resveratrol and estradiol on streptozotocin-induced diabetes in ovariectomized mice and the related mechanisms

analysis: Yanyu Lu. Investigation: Yunxia Li, Jinbing Huang, Yuan Yan, Jingjing Liang. Methodology: Jinbing Huang. Supervision: Hongfang Li. Writing ? original draft: Yunxia Li. Writing ? review

Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

, Hangzhou 310058, ChinaLinrong Lu AuthorsSearch for Jingjing Liang in:Nature Research journals • PubMed • Google ScholarSearch for Jun Lyu in:Nature Research journals • PubMed • Google ScholarSearch for Meng

Matrix Models for Size-Structured Populations: Unrealistic Fast Growth or Simply Diffusion?

Matrix population models are widely used to study population dynamics but have been criticized because their outputs are sensitive to the dimension of the matrix (or, equivalently, to the class width). This sensitivity is concerning for the population growth rate () because this is an intrinsic characteristic of the population that should not depend on the model specification. It...

Large-scale forest inventories of the United States and China reveal positive effects of biodiversity on productivity

Background With the loss of species worldwide due to anthropogenic factors, especially in forested ecosystems, it has become more urgent than ever to understand the biodiversity-ecosystem functioning relationship (BEFR). BEFR research in forested ecosystems is very limited and thus studies that incorporate greater geographic coverage and structural complexity are needed. Methods...

A Genome-wide study of blood pressure in African Americans accounting for gene-smoking interaction

• PubMed • Google ScholarSearch for Sharon L. R. Kardia in:Nature Research journals • PubMed • Google ScholarSearch for Donna Arnett in:Nature Research journals • PubMed • Google ScholarSearch for Jingjing ... Liang in:Nature Research journals • PubMed • Google ScholarSearch for Steven C. Hunt in:Nature Research journals • PubMed • Google ScholarSearch for D.C. Rao in:Nature Research journals • PubMed • Google

IL4I1 Is a Novel Regulator of M2 Macrophage Polarization That Can Inhibit T Cell Activation via L-Tryptophan and Arginine Depletion and IL-10 Production

Interleukin 4-induced gene-1 (IL4I1) was initially described as an early IL-4-inducible gene in B cells. IL4I1 protein can inhibit T cell proliferation by releasing its enzymatic catabolite, H2O2, and this effect is associated with transient down-regulation of T cell CD3 receptor-zeta (TCRζ) expression. Herein, we show that IL4I1 contributes to the regulation of macrophage...

An Efficient Schema for Cloud Systems Based on SSD Cache Technology

Traditional caching strategy is mainly based on the memory cache, taking read-write speed as its ultimate goal. However, with the emergence of SSD, the design ideas of traditional cache are no longer applicable. Considering the read-write characteristics and times limit of erasing, the characteristics of SSD are taken into account as far as possible at the same time of designing...

Biochemical and Ultrastructural Changes in the Hepatopancreas of Bellamya aeruginosa (Gastropoda) Fed with Toxic Cyanobacteria

This study was conducted to investigate ultrastructural alterations and biochemical responses in the hepatopancreas of the freshwater snail Bellamya aeruginosa after exposure to two treatments: toxic cyanobacterium (Microcystis aeruginosa) and toxic cyanobacterial cells mixed with a non-toxic green alga (Scendesmus quadricauda) for a period of 15 days of intoxication, followed by...

Clathrin and AP2 Are Required for Phagocytic Receptor-Mediated Apoptotic Cell Clearance in Caenorhabditis elegans

Clathrin and the multi-subunit adaptor protein complex AP2 are central players in clathrin-mediated endocytosis by which the cell selectively internalizes surface materials. Here, we report the essential role of clathrin and AP2 in phagocytosis of apoptotic cells. In Caenorhabditis elegans, depletion of the clathrin heavy chain CHC-1 and individual components of AP2 led to a...

Activation of p53-regulated pro-apoptotic signaling pathways in PrP-mediated myopathy

Background We have reported that doxycycline-induced over-expression of wild type prion protein (PrP) in skeletal muscles of Tg(HQK) mice is sufficient to cause a primary myopathy with no signs of peripheral neuropathy. The preferential accumulation of the truncated PrP C1 fragment was closely correlated with these myopathic changes. In this study we use gene expression profiling...