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The Protective Role of Brain CYP2J in Parkinson’s Disease Models

supporting research. Conflicts of Interest The authors declare no conflict of interest. Authors’ Contributions Yueran Li, Jinhua Wu, Shufang Na, and Xuming Yu performed the experiments. Yueran Li, Jinhua Wu ... published. Yueran Li and Jinhua Wu contributed equally to this work. Yueran Li and Jinhua Wu are co-first author. Acknowledgments The authors thank the members of the Animal Care Committee of Wuhan University

The Protective Role of Brain CYP2J in Parkinson’s Disease Models

supporting research. Conflicts of Interest The authors declare no conflict of interest. Authors’ Contributions Yueran Li, Jinhua Wu, Shufang Na, and Xuming Yu performed the experiments. Yueran Li, Jinhua ... be published. Yueran Li and Jinhua Wu contributed equally to this work. Yueran Li and Jinhua Wu are co-first author. Acknowledgments The authors thank the members of the Animal Care Committee of

Design of efficient simplified genomic DNA and bisulfite sequencing in large plant populations

authors Jinhua Wu, Zewei Luo and Ning Jiang declare that they have no conflict of interests. This article does not contain any studies with human or animal subjects performed by any of the authors. 1

Effects of Ionizing Radiation on Physical Properties of Peripherally Inserted Central Catheter

Peripherally inserted central catheter (PICC) has been widely used to treat cancer patients. It is unknown whether or not it can be applied safely during radiotherapy. The study aimed to investigate the direct effects of gamma radiation on physical properties of PICC. A total of 60 catheters were included in this study. Thirty PICCs were exposed to a radiation field, and another...

A highly robust and optimized sequence-based approach for genetic polymorphism discovery and genotyping in large plant populations

Advent of the next generation sequencing techniques motivates recent interest in developing sequence-based identification and genotyping of genome-wide genetic variants in large populations, with RAD-seq being a typical example. Without taking proper account for the fact that chloroplast and rRNA genes may occupy up to 60 % of the resulting sequence reads, the current RAD-seq...

A Signal Coordination Control Based on Traversing Empty between Mid-Block Street Crossing and Intersection

To solve the problem in pedestrian Mid-Block street crossing, the method of signal coordination control between mid-block street crossing and intersection is researched in this paper. The paper proposes to use “distance-flow rate-time” graph as the tool for building coordination control system model which is for different situations of traffic control. Through alternating the...

A Signal Coordination Control Based on Traversing Empty between Mid-Block Street Crossing and Intersection

To solve the problem in pedestrian Mid-Block street crossing, the method of signal coordination control between mid-block street crossing and intersection is researched in this paper. The paper proposes to use “distance-flow rate-time” graph as the tool for building coordination control system model which is for different situations of traffic control. Through alternating the...

Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion

, Philadelphia, Pennsylvania 19111, USAHao Zhang & Jinhua Wu AuthorsSearch for Jun Yang in:Nature Research journals • PubMed • Google ScholarSearch for Liang Zhu in:Nature Research journals • PubMed • Google ... in:Nature Research journals • PubMed • Google ScholarSearch for Edward F. Plow in:Nature Research journals • PubMed • Google ScholarSearch for Jinhua Wu in:Nature Research journals • PubMed • Google

Cellular and organellar membrane-associated proteins in haloarchaea: Perspectives on the physiological significance and biotechnological applications

Halophilic archaea (haloarchaea) inhabit hypersaline environments, tolerating extreme salinity, low oxygen and nutrient availability, and in some cases, high pH (soda lakes) and irradiation (saltern ponds). Membrane-associated proteins of haloarchaea, such as surface layer (S-layer) proteins, transporters, retinal proteins, and internal organellar membrane proteins including...

GPR48, a poor prognostic factor, promotes tumor metastasis and activates β-catenin/TCF signaling in colorectal cancer

G-protein-coupled receptor 48 (GPR48) is an orphan receptor belonging to the G-protein-coupled receptors family, which plays an important role in the development of various organs and cancer development and progression such as gastric cancer and colorectal cancer (CRC). However, the prognostic value of GPR48 expression in patients with CRC has not been reported. In this study, we...

Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid

Background The role of the epidermal growth factor receptor (EGFR) and other receptor tyrosine kinases (RTKs) in provoking biological actions of G protein-coupled receptors (GPCRs) has been one of the most disputed subjects in the field of GPCR signal transduction. The purpose of the current study is to identify EGFR-mediated mechanisms involved in activation of G protein...