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The trials and tribulations of conducting an m-health pilot randomized controlled trial to improve oral cancer therapy adherence: recommendations for future multisite, non-drug clinical trials

ObjectiveIntegrating mobile phone-based health (m-health) interventions into healthcare systems is one solution to improve access to services for the growing number of patients with chronic illness. Practical challenges such as poor recruitment and inadequate resource allocation can hamper the assessment of such interventions with clinical trial methodology. This paper highlights...

Circulating tumour DNA reflects treatment response and clonal evolution in chronic lymphocytic leukaemia

. Papenfuss, Mark A. Dawson & Sarah-Jane DawsonDivision of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, AustraliaPaul Yeh, David Westerman, Piers Blombery, John F. Seymour, Mark A ... , Andjelija Zivanovic, Rishu Agarwal, David Westerman, John F. Seymour, Anthony T. Papenfuss, Mark A. Dawson, Constantine S. Tam & Sarah-Jane DawsonDepartment of Radiology, Peter MacCallum Cancer Centre

Secondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan

Haruyuki Ishii John F Seymour Ryushi Tazawa 0 Yoshikazu Inoue Naoyuki Uchida Aya Nishida Yoshihito Kogure Takeshi Saraya Keisuke Tomii Toshinori Takada Yuko Itoh 0 Masayuki Hojo Toshio Ichiwata

Hardrock Mining and the Environment: Issues of Federal Enforcement and Liability

By John F. Seymour, Published on 09/01/04 ... ................................................................ A. Hardrock M ine Sites in the West ............................................. Copyright ? 2004 by the Regents of the University of California. * John F. Seymour is an attorney with the United

Negative selection of chronic lymphocytic leukaemia cells using a bifunctional rosette-based antibody cocktail

Background High purity of tumour samples is a necessity for accurate genetic and expression analysis and is usually achieved by positive selection in chronic lymphocytic leukaemia (CLL). Results We adapted a bifunctional rosette-based antibody cocktail for negative selection of B-cells for isolating CLL cells from peripheral blood (PB). PB samples from CLL patients were split...

Detection of NPM1 exon 12 mutations and FLT3 – internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia

Background Molecular characterisation of normal karyotype acute myeloid leukemia (NK-AML) allows prognostic stratification and potentially can alter treatment choices and pathways. Approximately 45–60% of patients with NK-AML carry NPM1 gene mutations and are associated with a favourable clinical outcome when FLT3-internal tandem duplications (ITD) are absent. High resolution...

Re: Cure of Helicobacter pylori Infection and Duration of Remission in Low-Grade Gastric Mucosa-Associated Lymphoid Tissue Lymphoma

other sites remain undetermined. JOHN F. SEYMOUR References (1) Neubauer A, Thiede C, Morgner A, Alpen B, Ritter M, Neubauer B, et al. Cure of Helicobacter pylori infection and duration of remission of