Confidence interval mTORC1 Mechanistic target of rapamycin complex 1 OR odds ratio Communicated by Mario Bianchetti Hilde K. Brekke and Johnny Ludvigsson acted as equivalent senior authors
curation: Johnny Ludvigsson. Formal analysis: Rachel E. J. Besser, Tim J. Cole. Funding acquisition: Johnny Ludvigsson. Investigation: Rachel E. J. Besser, Johnny Ludvigsson, Tim J. Cole. Methodology ... : Tim J. Cole. Project administration: Johnny Ludvigsson. Resources: Johnny Ludvigsson. Software: Tim J. Cole. Supervision: Tim J. Cole. Writing ± original draft: Rachel E. J. Besser, Tim J. Cole
Barcenilla,1 Jeannette Wahlberg,2 Peter Achenbach,3 Johnny Ludvigsson,1,4 and Rosaura Casas1 1Division of Pediatrics, Department of Clinical and Experimental Medicine, Faculty of Medicine and Health Sciences ... patient privacy. Disclosure The current address of Johnny Ludvigsson is Division of Pediatrics, Department of Clinical and Experimental Medicine, Medical Faculty of Linköping University, 581 85 Linköping
: Linda Åkerman. Conceptualization: Linda Åkerman, Johnny Ludvigsson, Camilla Skoglund. Formal analysis: Linda Åkerman, Beatriz Tavira, Camilla Skoglund. Funding acquisition: Rosaura Casas, Johnny ... Ludvigsson, Camilla Skoglund. Investigation: Linda Åkerman. Methodology: Linda Åkerman. Project administration: Linda Åkerman, Johnny Ludvigsson, Camilla Skoglund. Resources: Rosaura Casas, Johnny
We have developed high-throughput tests for the detection of the insulin gene region SNPs −23HphI and −2221MspI. The potential of these markers to enhance the efficiency of type 1 diabetes risk screening was then evaluated by analyzing them in Finnish and Swedish populations. Blood spots on filter paper were analyzed using PCR followed by sequence-specific hybridization and time...
project leader Johnny Ludvigsson, who can show where the minimal underlying data set for this study can be found in ABIS biobank register. Ethics The ABIS study has been approved by the Research Ethics
Drugs Author's Reply to Dayal: ''Therapies to Preserve b-Cell Function in Type 1 Diabetes'' Johnny Ludvigsson 0 1 0 Division of Pediatrics, Department of Clinical and Experimental Medicine, Linko ... ̈ping University , 58185 Linko ̈ping , Sweden 1 & Johnny Ludvigsson - In his comment [ 1 ] on ‘‘Therapies to Preserve b-Cell Function in Type 1 Diabetes’’ [ 2 ], Devi Dayal, while overall very
islet autoantibodies to insulin (IAA), GAD (GADA), tyrosine phosphatase 2 (IA-2A) and zinc transporter Paolo Pozzilli, Johnny Ludvigsson and Ahuva Nissim share senior authorship. Biomarker; Insulin
registration: ClinicalTrials.gov NCT00723411. Children; GAD; H1N1; Immune intervention; Type 1 diabetes; Vaccine - Johnny Ludvigsson and Rosaura Casas contributed equally to this study. Abbreviations GADA
Aim To further elucidate the relationship between physical activity and several risk factors for development of diabetes (glucose, C-peptide and obesity) over time. Methods A prospective longitudinal study where physical activity was measured on 199 children from Kalmar and Linköping at age 8, and the same 107 children from Linköping again at age 12. Anthropometric data was...
, Sweden 1 Johnny Ludvigsson and Annika Thorsell are joint last authors 2 Department of Medicine and Health Sciences, Community Medicine/General Practice, Linkoping University , Linkoping 58183 , Sweden 3
Aims/hypothesis GAD is a major target of the autoimmune response that occurs in type 1 diabetes mellitus. Randomised controlled clinical trials of a GAD + alum vaccine in human participants have so far given conflicting results. Methods In this study, we sought to see whether a clearer answer to the question of whether GAD65 has an effect on C-peptide could be reached by...
Johnny Ludvigsson 0 0 J. Ludvigsson (&) Division of Pediatrics, Department of Clinical and Experimental Medicine, Linkoping University , 58185, Linkoping, Sweden After 90 years of using insulin to
Johnny Ludvigsson 0 Anneli Frostell 0 0 J. Carstensen Division of Health and Society, Department of Medical and Health Sciences, Linköping University , Linköping , Sweden Aims/hypothesis The aim of this ... ; Stressful events; Type 1 diabetes mellitus - Johnny Ludvigsson and Anneli Frostell are joint senior authors on this paper. Introduction The aetiology behind type 1 diabetes is unknown, but both genetic
Background The infant microbiota may play a pathogenic role in coeliac disease (CD). Antibiotic treatment in pregnancy is common and could significantly impact the infant microbiota. In this study, we aimed to investigate the association between antibiotic exposure during pregnancy and CD in offspring. Methods Prospective questionnaire data on antibiotic exposure in pregnancy...
Meryl Dhir Mats Fredrikson Johnny Ludvigsson Hans J. Arnqvist RESEARCH DESIGN AND METHODS A longitudinal observation study followed an unselected population of 451 patients diagnosed with type 1 diabetes
Background:Type 1 diabetes (T1D) is a serious diagnosis with the prospect of grave short- and long-term complications and even death if poorly managed. An attempt has been made to describe how clinical and immunological deviations might influence each other close to the diagnosis of T1D.Methods:Sixty-nine newly diagnosed T1D children were studied together with a reference group...
OBJECTIVE GAD formulated in aluminum hydroxide (GAD-alum) has previously been shown to induce preservation of residual insulin secretion in recent-onset type 1 diabetes, but recent phase II and III GAD-alum trials failed to reach primary outcomes. The European phase III study was therefore closed after 15 months, and only a minority of patients completed the 30 months of follow-up.