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A high HIV-1 strain variability in London, UK, revealed by full-genome analysis: Results from the ICONIC project

Brown. Data curation: Jade Raffle, Jonathan Hubb, R. Bridget Ferns, Laura Waters, Zisis Kozlakidis, Andrew Hayward, Paul Kellam, Deenan Pillay, Duncan Clark, Eleni Nastouli. Formal analysis: Gonzalo ... , Jonathan Hubb, R. Bridget Ferns, Laura Waters, C. Y. William Tong, Zisis Kozlakidis, Andrew Hayward, Paul Kellam, Deenan Pillay, Duncan Clark, Eleni Writing ± original draft: Gonzalo Yebra, Andrew J. Leigh

Astrovirus VA1/HMO-C: An Increasingly Recognized Neurotropic Pathogen in Immunocompromised Patients

Background. An 18-month-old boy developed encephalopathy, for which extensive investigation failed to identify an etiology, 6 weeks after stem cell transplant. To exclude a potential infectious cause, we performed high-throughput RNA sequencing on brain biopsy. Methods. RNA-Seq was performed on an Illumina Miseq, generating 20 million paired-end reads. Nonhost data were checked...