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Three Years Down the Road: The Aftermath of the CDC Guideline for Prescribing Opioids for Chronic Pain

for the integrity of the work as a whole, and have given their approval for this version to be published. Disclosures Joseph V. Pergolizzi, Jr., Melanie Rosenblatt, and Jo Ann LeQuang have nothing to ... disclose. Joseph V. Pergolizzi, Jr., is a member of the journal’s Editorial Board. Compliance and Ethics Guidelines This article is based on previously conducted studies and does not contain any studies

The Role of Lofexidine in Management of Opioid Withdrawal

approval for this version to be published. Disclosures Joseph V. Pergolizzi Jr., Hani Annabi, Christopher Gharibo, and Jo Ann LeQuang have nothing to disclose. Compliance with Ethics Guidelines This

Tapentadol Extended Release in the Treatment of Severe Chronic Low Back Pain and Osteoarthritis Pain

responsibility for the integrity of the work as a whole, and have given their approval for this version to be published. Disclosures. Joseph V. Pergolizzi, Robert Taylor, Jr, Jo Ann LeQuang, Robert B. Raffa, and

Managing severe pain and abuse potential: the potential impact of a new abuse-deterrent formulation oxycodone/naltrexone extended-release product

Managing severe pain and abuse potential: the potential impact of a new abuse-deterrent formulation oxycodone/naltrexone extended‑release product Joseph V Pergolizzi, Jr,1 Robert Taylor Jr,1 Jo Ann

Pharmacokinetics of Oral and Intravenous Paracetamol (Acetaminophen) When Co-Administered with Intravenous Morphine in Healthy Adult Subjects

Pharmaceuticals Inc., Joseph V Pergolizzi Jr. is a consultant/ speaker and/ or researcher for: Inspirion, Mallinckrodt, Collegium, Purdue Pharma LLP, Grunenthal GmhB, Inspirion, ENDO Pharmaceuticals Iroko, DepoMed

The Basic Pharmacology of Opioids Informs the Opioid Discourse about Misuse and Abuse: A Review

Morphine and other opioids are widely used to manage moderate to severe acute pain syndromes, such as pain associated with trauma or postoperative pain, and they have been used to manage chronic pain, even chronic nonmalignant pain. However, recent years have seen a renewed recognition of the potential for overuse, misuse, and abuse of opioids. Therefore, prescribing opioids is...

Change Pain: Ever Evolving—An Update for 2016

Since 1986, the pharmacological management of pain was mainly based on the WHO “analgesic ladder”, with very few drugs available. The huge development of the basic knowledge on pain and its therapy, especially in the past 15 years, has made the “guidelines” of WHO obsolete. That’s why, during the presidency of EFIC of one of the authors (GV), an international advisory board was...

Management of moderate to severe chronic low back pain with buprenorphine buccal film using novel bioerodible mucoadhesive technology

Management of moderate to severe chronic low back pain with buprenorphine buccal film using novel bioerodible mucoadhesive technology Joseph V Pergolizzi Jr,1 Robert B Raffa,2,3 Charles Fleischer,1

The Potential Role of an Extended-Release, Abuse-Deterrent Oxycodone/Acetaminophen Fixed-Dose Combination Product for the Treatment of Acute Pain

Acute pain, prevalent as part of postoperative and traumatic pain, is often sub-optimally or inadequately treated. Fixed-dose combination analgesic products that combine a reduced amount of opioid with a nonopioid analgesic such as acetaminophen (paracetamol) in a single tablet offer potential pharmacodynamic and/or pharmacokinetic benefits, and may also result in an opioid...

Fast-Acting Sublingual Zolpidem for Middle-of-the-Night Wakefulness

; Accepted 2 November 2013; Published 5 February 2014 Academic Editor: Giora Pillar Copyright © 2014 Joseph V. Pergolizzi Jr. et al. This is an open access article distributed under the Creative Commons ... patients. Conflict of Interests Joseph V. Pergolizzi Jr. is a consultant for Purdue Pharma, Grünenthal, Endo, Pfizer, INSYS Therapeutics, Baxter, and is a consultant and on the speakers bureau for Lilly USA

Prophylaxis of Postoperative Nausea and Vomiting in Adolescent Patients: A Review with Emphasis on Combination of Fixed-Dose Ondansetron and Transdermal Scopolamine

2011; Accepted 9 May 2011 Academic Editor: Claudia Valenta Copyright © 2011 Joseph V. Pergolizzi et al. This is an open access article distributed under the Creative Commons Attribution License

Prophylaxis of Postoperative Nausea and Vomiting in Adolescent Patients: A Review with Emphasis on Combination of Fixed-Dose Ondansetron and Transdermal Scopolamine

April 2011; Accepted 9 May 2011 Academic Editor: Claudia Valenta Copyright © 2011 Joseph V. Pergolizzi et al. This is an open access article distributed under the Creative Commons Attribution

Pain Management in the Elderly: An FDA Safe Use Initiative Expert Panel’s View on Preventable Harm Associated with NSAID Therapy

A. Hartford Foundation; Jerry H. Gurwitz, MD; Joseph V. Pergolizzi, Jr., MD; Kenneth G. Saag, M.D. M.Sc.; Christina Spellman from the Mayday Fund; Barbara J. Zarowitz, PharmD, CGP, BPS, FCCP, FASCP ... . Pergolizzi Jr.3 1NEMA Research Inc., 840-111th Avenue North Suite no. 9, Naples, FL 34108, USA 2FDA Safe Use Initiative, (SUI), CDER, FDA, 11093 New Hampshire Avenue, Silver Spring, MD 20993, USA 3Department

Mitigating the risk of opioid abuse through a balanced undergraduate pain medicine curriculum

Mitigating the risk of opioid abuse through a balanced undergraduate pain medicine curriculum Patricia K Morley-Forster,1 Joseph V Pergolizzi,2–4 Robert Taylor Jr,4 Robert A Axford-Gatley,5 Edward M ... edward M Sellers 3 Department of Anesthesia and Perioperative Medicine, University of w estern Ontario , London, ON , Canada 4 Joseph v Pergolizzi 5 DL Global Partners inc , Toronto, ON , Canada 6 Clinical

Naltrexone extended-release injection: an option for the management of opioid abuse

Naltrexone extended-release injection: an option for the management of opioid abuse Robert Taylor Jr1, Robert B Raffa2, Joseph V Pergolizzi Jr3,41NEMA Research Inc, Naples, FL, 2Department of ... University School of Medicine , Baltimore, MD , USA 1 Department of Pharmaceutical Sciences, Temple University School of Pharmacy , Philadelphia, PA , USA 2 NeMA Research inc , Naples, FL , USA 3 Joseph v

Perspectives on the Role of Fospropofol in the Monitored Anesthesia Care Setting

February 2011 Academic Editor: Uwe Rudolph Copyright © 2011 Joseph V. Pergolizzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Perspectives on the Role of Fospropofol in the Monitored Anesthesia Care Setting

February 2011 Academic Editor: Uwe Rudolph Copyright © 2011 Joseph V. Pergolizzi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Anesthetic Routines: The Anesthesiologist's Role in GI Recovery and Postoperative Ileus

All patients undergoing bowel resection experience postoperative ileus, a transient cessation of bowel motility that prevents effective transit of intestinal contents or tolerance of oral intake, to varying degrees. An anesthesiologist plays a critical role, not only in the initiation of surgical anesthesia, but also with the selection and transition to effective postoperative...

Anesthetic Routines: The Anesthesiologist's Role in GI Recovery and Postoperative Ileus

All patients undergoing bowel resection experience postoperative ileus, a transient cessation of bowel motility that prevents effective transit of intestinal contents or tolerance of oral intake, to varying degrees. An anesthesiologist plays a critical role, not only in the initiation of surgical anesthesia, but also with the selection and transition to effective postoperative...

Fixed-dose combinations at the front line of multimodal pain management: perspective of the nurse-prescriber

Fixed-dose combinations at the front line of multimodal pain management: perspective of the nurse-prescriber Joanne O’Brien,1 Joseph V Pergolizzi Jr,2 Mart van de Laar3, Hans-Ulrich Mellinghoff,4