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Evolution of Hox gene clusters in deuterostomes

Hox genes, with their similar roles in animals as evolutionarily distant as humans and flies, have fascinated biologists since their discovery nearly 30 years ago. During the last two decades, reports on Hox genes from a still growing number of eumetazoan species have increased our knowledge on the Hox gene contents of a wide range of animal groups. In this review, we summarize...

Implications of duplicated cis-regulatory elements in the evolution of metazoans: the DDI model or how simplicity begets novelty

Senda Jime nez-Delgado Juan Pascual-Anaya Jordi Garcia-Fern a'ndez The discovery that most regulatory genes were conserved among animals from distant phyla challenged the ideas that gene duplication

Gene Expansion and Retention Leads to a Diverse Tyrosine Kinase Superfamily in Amphioxus

Tyrosine kinase (TK) proteins play a central role in cellular behavior and development of animals. The expansion of this superfamily is regarded as a key event in the evolution of the complex signaling pathways and gene networks of metazoans and is a prominent example of how shuffling of protein modules may generate molecular novelties. Using the intron/exon structure within the...

The draft genomes of soft-shell turtle and green sea turtle yield insights into the development and evolution of the turtle-specific body plan

genome project was supported by the China National GeneBank at BGI-Shenzhen. Author information Author notesZhuo Wang, Juan Pascual-Anaya, Amonida Zadissa & Wenqi Li These authors contributed equally ... , Denmark.Guojie Zhang AuthorsSearch for Zhuo Wang in:Nature Research journals • PubMed • Google ScholarSearch for Juan Pascual-Anaya in:Nature Research journals • PubMed • Google ScholarSearch for Amonida Zadissa