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Evolution of international collaborative research efforts to develop non-Cochrane systematic reviews

Ruano. Data curation: Macarena Aguilar-Luque, Jesu?s Gay-Mimbrera, Ana Montilla. Formal analysis: Isabel Viguera-Guerra, Juan Ruano. Funding acquisition: Juan Ruano. Methodology: Isabel Viguera-Guerra ... , Juan Luis Sanz-Cabanillas, Pedro Jesu?s Go?mez-Arias. Project administration: Isabel Viguera-Guerra, Juan Ruano. Resources: Isabel Viguera-Guerra, Ana Montilla. Software: Jose Luis Ferna?ndez-Rueda

A Scoping Review Protocol to Explore the Use of Interleukin-1-Targeting Drugs for the Treatment of Dermatological Diseases: Indications, Mechanism of Action, Efficacy, and Safety

´ mez-Garc´ıa and Juan Ruano contributed equally to this work. evidence-based guidelines rank interventions according to cost-effectiveness. However, evidence on this topic is scarce for several reasons ... ´ mez-Garc´ıa, Juan Ruano, Jesu´ s Gay-Mimbrera, Macarena AguilarLuqe, Juan L. Sanz-Cabanillas, Jose´ L. Herna´ndez Romero, and Antonio Velez Garcia-Nieto have nothing to disclose. Compliance with Ethics

The differential impact of scientific quality, bibliometric factors, and social media activity on the influence of systematic reviews and meta-analyses about psoriasis

. Conceptualization: Juan Ruano, Francisco GoÂmez-Garcia, Antonio VeÂlez GarcÂõa-Nieto, Beatriz Isla-Tejera. Data curation: Juan Ruano, Macarena Aguilar-Luque, Pedro J. Carmona-Fernandez, Juan LuÂõs Sanz-Cabanillas ... . Formal analysis: Juan Ruano, Macarena Aguilar-Luque, Francisco GoÂmez-Garcia, Jesus Gay Mimbrera, Pedro J. Carmona-Fernandez. Funding acquisition: Juan Ruano. Investigation: Juan Ruano, Macarena Aguilar

Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis

Scalp psoriasis shows a variable clinical spectrum and in many cases poses a great therapeutic challenge. However, it remains unknown whether the immune response of scalp psoriasis differs from understood pathomechanisms of psoriasis in other skin areas. We sought to determine the cellular and molecular phenotype of scalp psoriasis by performing a comparative analysis of scalp...

Clinical and Biological Principles of Cold Atmospheric Plasma Application in Skin Cancer

. Jesu´ s Gay-Mimbrera, Maria Carmen Garc´ıa, Beatriz Isla-Tejera, Antonio Rodero-Serrano, Antonio Ve´lez Garc´ıa-Nieto, and Juan Ruano have nothing to disclose. Compliance with Ethics Guidelines

Author-paper affiliation network architecture influences the methodological quality of systematic reviews and meta-analyses of psoriasis

Moderate-to-severe psoriasis is associated with significant comorbidity, an impaired quality of life, and increased medical costs, including those associated with treatments. Systematic reviews (SRs) and meta-analyses (MAs) of randomized clinical trials are considered two of the best approaches to the summarization of high-quality evidence. However, methodological bias can reduce...

Economic Evaluation of Botulinum Toxin Versus Thoracic Sympathectomy for Palmar Hyperhidrosis: Data from a Real-World Scenario

whole. No funding was involved in this study or the development of the manuscript. Conflict of interest. Beatriz Isla-Tejera, Mara A. Alvarez, Juan Ruano, Teresa Brieva, Manuel Cardenas, Carlos Baamonde

Long-Term Cost-Effectiveness Analysis of Etanercept and Adalimumab for Plaque Psoriasis not Associated with Arthritis

Introduction Pharmacoeconomic studies examining the cost-effectiveness of biological agents to treat moderate-to-severe psoriasis in real-life clinical practice are scarce. The aim of this study was to assess the efficiency, in terms of incremental cost-effectiveness, of etanercept and adalimumab in a real clinical setting. Methods Direct and indirect costs were assessed from a...

Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil

Background Previous studies have shown that acute intake of high-phenol virgin olive oil reduces pro-inflammatory, pro-oxidant and pro-thrombotic markers compared with low phenols virgin olive oil, but it still remains unclear whether effects attributed to its phenolic fraction are exerted at transcriptional level in vivo. To achieve this goal, we aimed at identifying expression...