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4 papers found.
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The matricellular protein CCN5 inhibits fibrotic deformation of retinal pigment epithelium

. Methodology: Sora Im, Juyeon Lee, Daeho Park. Supervision: Jeong Hun Kim. Validation: Jin Hyoung Kim. Writing – original draft: Aeri Yoon, Woo Jin Park. Writing – review & editing: Dong Hyun Jo. 13 / 15 14

Effect of the Number of Pregnancies on Mortality Risk in HIV-Infected Women: a Prospective Cohort Study in Rural KwaZulu-Natal, South Africa

We investigated whether mortality risk increases with the number of full-term pregnancies in HIV-infected women. Our study is based on data from the ACDIS cohort, collected in rural KwaZulu-Natal, South Africa. Mortality risk for different number of pregnancies in HIV-infected women was analyzed using Cox proportional hazards model. The risk of TB or AIDS mortality in HIV...

Intermolecular steric inhibition of Ephexin4 is relieved by Elmo1

Ephexin4, a guanine nucleotide-exchange factor for RhoG, promotes engulfment of apoptotic cells and cancer cell migration in a RhoG-dependent manner, which is synergistically augmented by Elmo1, an Ephexin4-interacting protein. However, the underlying molecular mechanism remains elusive. Here, we report a mechanism by which Elmo1 cooperates with Ephexin4 to activate RhoG. We...

Escherichia coli YmdB regulates biofilm formation independently of its role as an RNase III modulator

Background Ribonuclease III (RNase III) activity modulates hundreds of genes in Escherichia coli (E. coli). YmdB, a member of the macrodomain protein family, is one of known trans-acting regulators of RNase III activity; however, the significance of its regulatory role in specific bacterial cellular processes and related genes has not been determined. YmdB overexpression was used...