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Search: authors:"Ka-Kui Chan"

2 papers found.
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RanGTPase: A Candidate for Myc-Mediated Cancer Progression

Background Ras-related nuclear protein (Ran) is required for cancer cell survival in vitro and human cancer progression, but the molecular mechanisms are largely unknown.

TWIST modulates prostate cancer cell-mediated bone cell activity and is upregulated by osteogenic induction

TWIST, a helix-loop-helix transcription factor, is highly expressed in many types of human cancer. We have previously found that TWIST confers prostate cancer cells with an enhanced metastatic potential through promoting epithelial–mesenchymal transition (EMT) and a high TWIST expression in human prostate cancer is associated with an increased metastatic potential. The...