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24 papers found.
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Interaction of the primordial germ cell-specific protein C2EIP with PTCH2 directs differentiation of embryonic stem cells via HH signaling activation

University, Yangzhou, Jiangsu, 225009, P.R. ChinaQisheng Zuo, Kai Jin, Yani Zhang, Guohong Chen & Bichun LiAnimal & Avian Sciences, University of Maryland, Baltimore, MD, 20741, USAJiuzhou Song AuthorsSearch ... for Qisheng Zuo in:Nature Research journals • PubMed • Google Scholar Search for Kai Jin in:Nature Research journals • PubMed • Google Scholar Search for Jiuzhou Song in:Nature Research journals

Breastfeeding and maternal cardiovascular risk factors and outcomes: A systematic review

Cochrane collaboration for assessing risk of Author Contributions Conceptualization: Binh Nguyen, Kai Jin, Ding Ding. Data curation: Binh Nguyen. Formal analysis: Binh Nguyen, Kai Jin. Investigation ... : Binh Nguyen. Methodology: Binh Nguyen, Ding Ding. Supervision: Ding Ding. Visualization: Binh Nguyen, Ding Ding. Writing ± original draft: Binh Nguyen, Kai Jin, Ding Ding. Writing ± review & editing

Computing the Pattern Waiting Time: A Revisit of the Intuitive Approach

We revisit the waiting time of patterns in repeated independent experiments. We show that the most intuitive approach for computing the waiting time, which reduces it to computing the stopping time of a Markov chain, is optimum from the perspective of computational complexity. For the single pattern case, this approach requires us to solve a system of m linear equations, where m...

Antioxidant and Anti-Inflammatory Flavonoids from the Flowers of Chuju, a Medical Cultivar of Chrysanthemum Morifolim Ramat

. Chuju were collected in October 2015 from Chuzhou, Anhui Province, China, and identified by Prof. Kai-Jin Wang at School of Life Sciences, Anhui University, where a voucher specimen (No. 2015-10-01) was

Transcriptional analysis of the conidiation pattern shift of the entomopathogenic fungus Metarhizium acridum in response to different nutrients

Background Most fungi, including entomopathogenic fungi, have two different conidiation patterns, normal and microcycle conidiation, under different culture conditions, eg, in media containing different nutrients. However, the mechanisms underlying the conidiation pattern shift are poorly understood. Results In this study, Metarhizium acridum undergoing microcycle conidiation on...

Celecoxib normalizes the tumor microenvironment and enhances small nanotherapeutics delivery to A549 tumors in nude mice

, our findings may have great potential in clinics to improve solid tumor treatment. 1 0 1 1 Author Contributions Bo Zhang, Kai Jin and Xianping Liu designed and performed the experiments, collected and

Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles

Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles Jifu Hao,* Tiantian Tong,* Kai Jin, Qiannan ... of Pharmacy, Taishan Medical University , Taian, People's republic of china 1 Kai Jin Qiannan Zhuang Te han Yanping Bi Jianzhu Wang Xiaodan Wang A folic acid (FA)-functionalized drug vehicle platform

Angiopep-2-conjugated poly(ethylene glycol)-co-poly(ε-caprolactone) polymersomes for dual-targeting drug delivery to glioma in rats

Angiopep-2-conjugated poly(ethylene glycol)-co-poly(e-caprolactone) polymersomes for dual-targeting drug delivery to glioma in rats Fei Lu,1,2 Zhiyong Pang,2,3 Jingjing Zhao,2 Kai Jin,4 Haichun Li,2

Decreased miR-503 expression in gastric cancer is inversely correlated with serum carcinoembryonic antigen and acts as a potential prognostic and diagnostic biomarker

Huang, Kai Jin, Haowei Hu, Jie Yu, Yu Zeng Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Wenzhou Medical University, Ruian, People’s Republic of China Background: Altered

Distribution of Cathepsin K in Late Stage of Tooth Germ Development and Its Function in Degrading Enamel Matrix Proteins in Mouse

Wei-Guang Wang Xin Jiang 0 Xuan Wen Kai-Jin Hu 0 Yang Xue 0 0 State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases &Shaanxi Clinical Research Center for

Liposomal C6 Ceramide Activates Protein Phosphatase 1 to Inhibit Melanoma Cells

Melanoma is one common skin cancer. In the present study, the potential anti-melanoma activity by a liposomal C6 ceramide was tested in vitro. We showed that the liposomal C6 (ceramide) was cytotoxic and anti-proliferative against a panel of human melanoma cell lines (SK-Mel2, WM-266.4 and A-375 and WM-115). In addition, liposomal C6 induced caspase-dependent apoptotic death in...

Comparison of the cellular transport mechanism of cationic, star-shaped polymers and liposomes in HaCat cells

Comparison of the cellular transport mechanism of cationic, star-shaped polymers and liposomes in HaCat cells Heng-Cong Luo,1,2,* Na Li,1,* Li Yan,1 Kai-jin Mai,3 Kan Sun,1 Wei Wang,1 Guo-Juan Lao,1

Carotid blowout syndrome after nasopharyngeal carcinoma radiotherapy: successful treatment by internal carotid artery occlusion after stent implantation failure

Introduction Carotid blowout syndrome (CBS) secondary to radiation therapy is life-threatening and requires emergency treatment. More recently, endovascular treatment has provided an effective way to control CBS-related bleeding. Case description We present a case of CBS with a rupture of the internal carotid artery (ICA) pseudo-aneurysm after Gamma Knife radiation therapy for...

Vision-Related Quality of Life and Appearance Concerns Are Associated with Anxiety and Depression after Eye Enucleation: A Cross-Sectional Study

Aims To investigate the association of demographic, clinical and psychosocial variables with levels of anxiety and depression in participants wearing an ocular prosthesis after eye enucleation. Methods This cross-sectional study included 195 participants with an enucleated eye who were attending an ophthalmic clinic for prosthetic rehabilitation between July and November 2014...

Influence of the lateral pterygoid muscle on traumatic temporomandibular joint bony ankylosis

Background The pathogenesis of traumatic TMJ ankylosis remains unclear. This study aimed to verify the role of the lateral pterygoid muscle in the pathogenesis of traumatic temporomandibular joint (TMJ) bony ankylosis. Methods Eight 6-month-old male sheep were used in this study. Bilateral TMJ osteotomies were performed to induce sagittal fractures of the mandibular condyle. The...

The Induction Effect of Am80 and TSA on ESC Differentiation via Regulation of Stra8 in Chicken

Stra8 encodes stimulated by retinoic acid gene 8, a protein that is important for initiation of meiosis in mammals and birds. This study was aimed at identifying the active control area of chicken STRA8 gene core promoter, to screen optimum inducers of the STRA8 gene, thus to enhance the differentiation of embryonic stem cells (ESCs) into spermatogonial stem cells. Fragments of...

Suitable hepatitis B vaccine for adult immunization in China

The aim of this study was to evaluate, in adults, the immunogenicity of six hepatitis B vaccines with different doses or different manufacturers in the Chinese market and to provide evidence to support adult hepatitis B vaccination. Participants were randomly divided into six groups (I–VI). Six vaccines (4 at 10 μg/dose and 2 at 20 μg/dose) were administered intramuscularly to...

Gene Expression Profiling via Multigene Concatemers

We established a novel method, Gene Expression Profiling via Multigene Concatemers (MgC-GEP), to study multigene expression patterns simultaneously. This method consists of the following steps: (1) cDNA was obtained using specific reverse primers containing an adaptor. (2) During the initial 1–3 cycles of polymerase chain reaction (PCR), the products containing universal adaptors...

Study on the Regulatory Mechanism of the Lipid Metabolism Pathways during Chicken Male Germ Cell Differentiation Based on RNA-Seq

Here, we explore the regulatory mechanism of lipid metabolic signaling pathways and related genes during differentiation of male germ cells in chickens, with the hope that better understanding of these pathways may improve in vitro induction. Fluorescence-activated cell sorting was used to obtain highly purified cultures of embryonic stem cells (ESCs), primitive germ cells (PGCs...