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Directional transport of centimeter-scale object on anisotropic microcilia surface under water

areas of micro-nano fluid mechanics and aerospace propulsion theory and engineering. Kang Sun is currently an associate research professor at Sun Yat-sen University. He received his PhD degree from the

Down-regulation of PDK4 is Critical for the Switch of Carbohydrate Catabolism during Syncytialization of Human Placental Trophoblasts

Qu Kang Sun OPEN Pyruvate dehydrogenase kinase (PDK) is known as a gatekeeper directing the carbon flux into glycolysis via inhibition of the pyruvate dehydrogenase complex. During syncytialization ... /4.0/. This work was supported by National Natural Science Foundation of China (grant number 81601286 to Rujuan Zuo; 31671566 to Kang Sun) . Additional Information Supplementary information accompanies

Nanoscale polysaccharide derivative as an AEG-1 siRNA carrier for effective osteosarcoma therapy

Nanoscale polysaccharide derivative as an AEG-1 siRNA carrier for effective osteosarcoma therapy Fen Wang,1,* Jia-Dong Pang,2,* Lei-lei Huang,1 Ran Wang,1 Dan Li,3 Kang Sun,4 Lian-tang Wang,1,* Li ... . 8 3 . 4 5 y b / m o c . s s e r p e v PowerdbyTCPDF(ww.tcpdf.org) O r I g I N a l r e s e a r c h lei-lei huang 1 ran Wang 1 Dan li 3 Kang sun 4 *These authors contributed equally to this work

Induction of pro-inflammatory genes by serum amyloid A1 in human amnion fibroblasts

• PubMed • Google Scholar Search for Hao Ying in:Nature Research journals • PubMed • Google Scholar Search for Kang Sun in:Nature Research journals • PubMed • Google Scholar Contributions W.L., W.W. and ... the manuscript. All authors reviewed the manuscript. Competing Interests The authors declare that they have no competing interests. Corresponding author Correspondence to Kang Sun. Electronic

Meta-Analysis of the Association between Tea Intake and the Risk of Cognitive Disorders

Background Alzheimer’s disease is a common neurodegenerative disorder in elderly. This study was aimed to systematically evaluate the association between tea intake and the risk of cognitive disorders by meta-analysis. Methods and Findings PubMed, Embase and Wanfang databases were systematically searched and a total of 26 observational studies were included in this study. Odds...

Nanostructured Surface with Tunable Contact Angle Hysteresis for Constructing In Vitro Tumor Model

, Guangzhou, Guangdong 510006, China Received 13 May 2016; Accepted 26 May 2016 Academic Editor: Liqian Gao Copyright © 2016 Kang Sun et al. This is an open access article distributed under the Creative

Nanostructured Surface with Tunable Contact Angle Hysteresis for Constructing In Vitro Tumor Model

, Guangzhou, Guangdong 510006, China Received 13 May 2016; Accepted 26 May 2016 Academic Editor: Liqian Gao Copyright © 2016 Kang Sun et al. This is an open access article distributed under the Creative

A High-Order Statistical Tensor Based Algorithm for Anomaly Detection in Hyperspectral Imagery

Application System, Institute of Electronics, Chinese Academy of Sciences, Beijing, ChinaXiurui Geng, Kang Sun & Yongchao ZhaoMinistry of Education Key Laboratory for Earth System Modelling, Centre for Earth ... System Science, Tsinghua University, Beijing, ChinaLuyan Ji AuthorsSearch for Xiurui Geng in:Nature Research journals • PubMed • Google ScholarSearch for Kang Sun in:Nature Research journals • PubMed

Cross-Talk between cAMP and MAPK Pathways in HSD11B2 Induction by hCG in Placental Trophoblasts

complicated cross-talk between hCG/cAMP and MAPK cascades in the regulation of placental HSD11B2 expression. - Competing Interests: Co-author Kang Sun is a PLOS ONE Editorial Board member. This does not alter

Diffusion of self-assembled monolayers of thiols on the gold surfaces covered with polydimethylsiloxane stamps

Thiols can diffuse and form self-assembled monolayers (SAMs) on the gold surfaces covered with polydimethylsiloxane (PDMS) stamps. For the first time, with cells as the indicator of how far alkanethiols had diffused to form SAM, we studied the growth dynamics of SAMs of HS(CH2)11(OCH2CH2)3OH (EG3) and HS(CH2)11(OCH2CH2)6OH (EG6) on the gold surfaces covered with PDMS stamps. The...

Effect of Acteoside as a Cell Protector to Produce a Cloned Dog

Somatic cell nuclear transfer (SCNT) is a well-known laboratory technique. The principle of the SCNT involves the reprogramming a somatic nucleus by injecting a somatic cell into a recipient oocyte whose nucleus has been removed. Therefore, the nucleus donor cells are considered as a crucial factor in SCNT. Cell cycle synchronization of nucleus donor cells at G0/G1 stage can be...

Sexually Dimorphic Effects of Maternal Nutrient Reduction on Expression of Genes Regulating Cortisol Metabolism in Fetal Baboon Adipose and Liver Tissues

Maternal nutrient reduction (MNR) during fetal development may predispose offspring to chronic disease later in life. Increased regeneration of active glucocorticoids by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in metabolic tissues is fundamental to the developmental programming of metabolic syndrome, but underlying mechanisms are unknown. Hexose-6-phosphate...

Application of liposomes in drug development – focus on gastroenterological targets

Application of liposomes in drug development – focus on gastroenterological targets Jian-Xin Zhang,1 Kun Wang,1 Zheng-Fa Mao,1 Xin Fan,1 De-Li Jiang,2 Min Chen,2 Lei Cui,1 Kang Sun,1 Sheng-Chun Dang1

Neuronal cell differentiation of mesenchymal stem cells originating from canine amniotic fluid

The amniotic fluid contains mesenchymal stem cells (MSCs) and can be readily available for tissue engineering. Regenerative treatments such as tissue engineering, cell therapy, and transplantation show potential in clinical trials of degenerative diseases. Disease presentation and clinical responses in the Canis familiaris not only are physiologically similar to human compared...

Surface Coating as a Key Parameter in Engineering Neuronal Network Structures In Vitro

By quantitatively comparing a variety of macromolecular surface coating agents, we discovered that surface coating strongly modulates the adhesion and morphogenesis of primary hippocampal neurons and serves as a switch of somata clustering and neurite fasciculation in vitro. The kinetics of neuronal adhesion on poly-lysine-coated surfaces is much faster than that on laminin and...

Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila

Background We observed previously that cisplatin-resistant HeLa cells were cross-resistant to UV light due to accumulation of DDB2, a protein implicated in DNA repair. More recently, we found that cFLIP, which represents an anti-apoptotic protein whose level is induced by DDB2, was implicated in preventing apoptosis induced by death-receptor signaling. In the present study, we...

Discovery of N-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide (sulcardine) as a novel anti-arrhythmic agent

KANG performed the chemical synthesis; Yueli DONG, Wei-kang SUN, and Yi-ping WANG performed the animal assays; Wei WANG and Yi-ping WANG performed npg the assays in vitro; Dong-lu BAI and Yi-ping WANG