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Search: authors:"Katarzyna Roszek"

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New strategy of controlled, stepwise release from novel MBioF and its potential application for drug delivery systems

Metal organic structures have gained recently an interest in many fields. Among them, metal–biomolecule framework materials with amino acids applied as organic linkers have attracted the growing attention. An application of tailored metal–biomolecule frameworks, easily decomposing in an acidic and/or reductive environment in a steerable way, is reported here. From these...

Controlling enzymatic activity by immobilization on graphene oxide

In this study, graphene oxide (GO) has been applied as a matrix for enzyme immobilization. The protein adsorption capacity of GO is much higher than of other large surface area carbonaceous materials. Its structure and physicochemical properties are reported beneficial also for enzymatic activity modifications. The experimental proof was done here that GO-based biocatalytic...

Comment on ‘‘Elucidating the binding efficacy of β-galactosidase on graphene by docking approach and its potential application in galacto-oligosaccharide production”

In a recent study, Satar et al. (Bioprocess Biosyst Eng 39:807–814, 2016) have reported “the synthesis and characterization of graphene for the immobilization of β-galactosidase for improved galacto-oligosaccharide (GOS) production”. There are several issues in this study that must be commented.

The role of purinergic signaling in the etiology of migraine and novel antimigraine treatment

Etiopathogenesis of migraine involves different structures of the central nervous system: the trigeminal nerve with nuclei located in the brain stem, vascular system, and the cerebral cortex as well as diverse mechanisms and pathological processes. The multidirectional action of purines in different cell types (blood vessels, neurons, and satellite glial cells) and through...

Conscious Changes of Carbon Nanotubes Cytotoxicity by Manipulation with Selected Nanofactors

We discuss eight major challenges in the field of carbon nanomaterial toxicity. Generally, we pick up some of them, and the most important challenge is searching of the qualitative relationships between nanofactors and cytotoxicity. This is important since it can provide the possibility of conscious changes of carbon nanotubes cytotoxicity by manipulation with selected...

Biologically Active Constituents from Salix viminalis Bio-Oil and Their Protective Activity Against Hydrogen Peroxide-Induced Oxidative Stress in Chinese Hamster Ovary Cells

The protective antioxidative effect of the phenolic extract (PE) isolated from Salix viminalis pyrolysis derived bio-oil was shown in vitro on the Chinese hamster ovary (CHO) cells exposed to hydrogen peroxide (H2O2). Cells pretreated with 0.05 μg/ml PE after exposure to different concentrations of H2O2 (300–900 μM) showed up to 25 % higher viability than the unpretreated ones...

Some aspects of purinergic signaling in the ventricular system of porcine brain

Background Numerous signaling pathways function in the brain ventricular system, including the most important - GABAergic, glutaminergic and dopaminergic signaling. Purinergic signalization system - comprising nucleotide receptors, nucleotidases, ATP and adenosine and their degradation products - are also present in the brain. However, the precise role of nucleotide signalling...