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14 papers found.
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Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

BackgroundThe changes that occur during puberty have been implicated in susceptibility to a wide range of diseases later in life, many of which are characterized by sex-specific differences in prevalence. Both genetic and environmental factors have been associated with the onset or delay of puberty, and recent evidence has suggested a role for epigenetic changes in the initiation...

Development of a Point Pyroshock Source Simulator

We developed a point pyroshock source simulator (PPSS) for the study on the source isolation approach (SIA) in this study. In spite of the potentiality of the SIA for avionics protection against pyroshock, it has rarely been investigated due to lack of pyroshock source simulators. To overcome such a situation, we proposed the PPSS using a mechanically excited tuned resonator...

Evaluation of drug mechanism and efficacy of a novel anti-angiogenic agent, TTAC-0001, using multi-modality bioimaging in a mouse breast cancer orthotopic model

Education(2016R1D1A1A02937258). Author Contributions Conceptualization: Sang Hyun Choi, Kyung Won Kim, Yoonseok Choi. Data curation: Jinil Kim, Su Jung Ham, Young Chul Cho, Seul-I Lee, Jeeheon Kang. Formal ... analysis: Jinil Kim, Sang Hyun Choi, Su Jung Ham, Seul-I Lee, Jeeheon Kang, Dong Cheol Woo, Kyung Won Kim, Yoonseok Choi. Funding acquisition: Yoonseok Choi. Investigation: Jinil Kim, Sang Hyun Choi, Su

Lung Clearance Index and Quantitative Computed Tomography of Post-Infectious Bronchiolitis Obliterans in Infants

Post-infectious bronchiolitis obliterans (BO) could be diagnosed via spirometry and chest computed tomography (CT); however, these tests are limited in infants. We aimed to evaluate the utility of lung clearance index (LCI) and air-trapping lung volume from chest CT in infants. This prospective study included 20 infants (mean age, 10.9 ± 6.3 months) diagnosed with post-infectious...

Smartphone-Driven Low-Power Light-Emitting Device

Low-level light (laser) therapy (LLLT) has been widely researched in the recent past. Existing LLLT studies were performed based on laser. Recently, studies using LED have increased. This study presents a smartphone-driven low-power light-emitting device for use in colour therapy as an alternative medicine. The device consists of a control unit and a colour probe. The device is...

Coordinated inhibition of C/EBP by Tribbles in multiple tissues is essential for Caenorhabditis elegans development

Background Tribbles proteins are conserved pseudokinases that function to control kinase signalling and transcription in diverse biological processes. Abnormal function in human Tribbles has been implicated in a number of diseases including leukaemia, metabolic syndromes and cardiovascular diseases. Caenorhabditis elegans Tribbles NIPI-3 was previously shown to activate host...

Serum anion gap at admission as a predictor of mortality in the pediatric intensive care unit

An accurate method to predict the mortality in the intensive care unit (ICU) patients has been required, especially in children. The aim of this study is to evaluate the value of serum anion gap (AG) for predicting mortality in pediatric ICU (PICU). We reviewed a data of 461 pediatric patients were collected on PICU admission. Corrected anion gap (cAG), the AG compensated for...

The administration of hydrogen sulphide prior to ischemic reperfusion has neuroprotective effects in an acute stroke model

analysis: Chul-Woong Woo. Funding acquisition: Hyun Kwon Ha, Dong-Cheol Woo. Investigation: Chul-Woong Woo, Jae-Im Kwon, Kyung-Won Kim, Jeong-Kon Kim, Sang Tae Kim, Su Jeong Ham. Methodology: Chul-Woong ... Woo, Jae-Im Kwon, Sang-Beom Jeon, Jinil Kim. Project administration: Jae-Im Kwon, Yoonseok Choi. Supervision: Kyung-Won Kim, Jeong-Kon Kim, Sang-Beom Jeon, Seung-Chae Jung, Choong-Gon Choi, Hyun Kwon

Numerical investigation on composite porous layers in electroosmotic flow

INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING-GREEN TECHNOLOGY Numerical Investigation on Composite Porous Layers in Electroosmotic Flow Taqi Ahmad Cheema 0 Kyung Won Kim 0 Moon

Neurochemical Changes Associated with Stress-Induced Sleep Disturbance in Rats: In Vivo and In Vitro Measurements

The goal of this study was to quantitatively assess the changes in the cerebral neurochemical profile and to identify those factors that contribute to the alteration of endogenous biomolecules when rats are subjected to stress-induced sleep disturbance. We exposed Sprague-Dawley rats (controls: n = 9; stress-induced sleep perturbation rats: n = 11) to a psychological stressor...

Additive Effect between IL-13 Polymorphism and Cesarean Section Delivery/Prenatal Antibiotics Use on Atopic Dermatitis: A Birth Cohort Study (COCOA)

Background Although cesarean delivery and prenatal exposure to antibiotics are likely to affect the gut microbiome in infancy, their effect on the development of atopic dermatitis (AD) in infancy is unclear. The influence of individual genotypes on these relationships is also unclear. To evaluate with a prospective birth cohort study whether cesarean section, prenatal exposure to...

Inhalation Toxicity of Humidifier Disinfectants as a Risk Factor of Children’s Interstitial Lung Disease in Korea: A Case-Control Study

Background The occurrence of numerous cases of interstitial lung disease in children (chILD) every spring in Korea starting in 2006 raised suspicion about a causal relationship with the use of humidifier disinfectants (HDs). The aim of this study was to evaluate the association between HD use and the risk of chILD. Methods This retrospective, 1∶3 matched case-control study...