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A New Similarity Measure between Intuitionistic Fuzzy Sets and Its Application to Pattern Recognition

As a generation of ordinary fuzzy set, the concept of intuitionistic fuzzy set (IFS), characterized both by a membership degree and by a nonmembership degree, is a more flexible way to cope with the uncertainty. Similarity measures of intuitionistic fuzzy sets are used to indicate the similarity degree between intuitionistic fuzzy sets. Although many similarity measures for...

Timosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating bile acid transporters

internalized by acute oxi- Lei-lei MA, and Xuan NI performed the experiments; Zhidative stress[ 39, 40 ], but there has been no direct connection tao WU, Xin-ming QI, and Jin REN analyzed the data; Zhi-tao

Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes

LIN designed the research; Lei-lei CHEN, Jun-chao WU, and Lin-hui WANG performed the research; Dr Zheng-Hong QIN, Dr Marian DIFIGILA, and Dr Jin WANG revised the paper. References 1. Li H, Li S ... , MA 02129, USAMarian Difiglia AuthorsSearch for Lei-lei Chen in:Nature Research journals • PubMed • Google ScholarSearch for Jun-chao Wu in:Nature Research journals • PubMed • Google ScholarSearch for

Improved Surface Wettability of Water by Applying SiC/Ti6Al4V Coatings on Carbon/Carbon Composites

Copyright © 2013 Lei-Lei Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

The analysis of groundwater levels influenced by dual factors in western Jilin Province by using time series analysis method

To enhance our understanding of the dynamic characteristics of groundwater level in the western Jilin Province of China, two models of decomposition method in time series analysis, additive model and multiplicative model, are employed in this study. The data used in the models are the monthly groundwater levels of three wells observed from 1986 to 2011. Moreover, the analysis of...

Association analyses confirm five susceptibility loci for systemic lupus erythematosus in the Han Chinese population

Introduction Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. Currently, numerous genetic loci of SLE have been confirmed. Here we try to further explore additional genes contributing to SLE susceptibility in this study. Methods Forty nine single nucleotide polymorphisms (SNPs) with moderate-risk for SLE in previous study were genotyped in a large-scale...

Intensity-dependent effect of treadmill running on lubricin metabolism of rat articular cartilage

Introduction We aimed to understand the changes in cartilage lubricin expression and immunolocalisation in responsed to treadmill running with different intensities in a rat model. Methods A total of 24 male Wistar rats were randomly assigned into groups of control (CON), low-intensity running (LIR), moderate-intensity running (MIR), and high-intensity running (HIR). Rats in LIR...

Matrix metalloproteinase-3 inhibitor retards treadmill running-induced cartilage degradation in rats

Introduction The effect of intra-articular injection of matrix metalloproteinase (MMP)-3 inhibitor was investigated in a rat model to understand the role of MMP-3 in cartilage degradation induced by excessive loading from running. Methods A total of 24 male Wistar rats were randomly assigned into groups of sedentary control (SED), high-intensity running (HIR), HIR + low dosage of...

Microbial synthesized biodegradable PHBHHxPEG hybrid copolymer as an efficient intracellular delivery nanocarrier for kinase inhibitor

Background Protein Kinases are key regulators of cell function and play essential roles in the occurrence and development of many human diseases. Many kinase inhibitors have been used for molecular targeted treatment of those diseases such as cancer and inflammation. However, those highly hydrophobic kinase inhibitors shared the common features of poor bioavailability and limited...

Heterologous expression of human costimulatory molecule B7-2 and construction of B7-2 immobilized polyhydroxyalkanoate nanoparticles for use as an immune activation agent

Ming-Chuan Li 0 Qian-Qian Liu 0 Xiao-Yun Lu Ya-Li Zhang Lei-Lei Wang 0 Equal contributors Department of Biological Science and Bioengineering, Key Laboratory of Biomedical Information Engineering of

Effects of dimethyl sulfoxide on asymmetric division and cytokinesis in mouse oocytes

Background Dimethyl sulfoxide (DMSO) is used extensively as a permeable cryoprotectant and is a common solvent utilized for several water-insoluble substances. DMSO has various biological and pharmacological activities; however, the effect of DMSO on mouse oocyte meiotic maturation remains unknown. Results In DMSO-treated oocytes, we observed abnormal MII oocytes that contained...

The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol

Background The periplasmic High Temperature Requirement protein A (HtrA) plays important roles in bacterial protein folding and stress responses. However, the role of chlamydial HtrA (cHtrA) in chlamydial pathogenesis is not clear. Results The cHtrA was detected both inside and outside the chlamydial inclusions. The detection was specific since both polyclonal and monoclonal anti...

Antibodies from women urogenitally infected with C. trachomatis predominantly recognized the plasmid protein pgp3 in a conformation-dependent manner

Background C. trachomatis organisms carry a cryptic plasmid that encodes 8 open reading frames designated as pORF1 to 8. It is not clear whether all 8 pORFs are expressed during C. trachomatis infection in humans and information on the functionality of the plasmid proteins is also very limited. Results When antibodies from women urogenitally infected with C. trachomatis were...

Relationship between body mass index and depressive symptoms: the “fat and jolly” hypothesis for the middle-aged and elderly in China

Li Zhuo Chen Li-li Zhang Lei-lei Guo 0 0 Department of Surgical Nursing, School of Nursing, Jinzhou Medical University , No.40, Section 3, Songpo Road, Linghe District, Jinzhou City, Liaoning Province ... authors are grateful to Kun Liu, Hong Li, Dan Li, Zhuo Chen, Li-li Zhang, and Lei-lei Guo. We thank the members of the CHARLS. Funding Collection of the CHARLS datasets used in the current study was

ID1-induced p16/IL6 axis activation contributes to the resistant of hepatocellular carcinoma cells to sorafenib

Lei-lei Niu in:Nature Research journals • PubMed • Google Scholar Search for Chuan-le Cheng in:Nature Research journals • PubMed • Google Scholar Search for Ming-Yue Li in:Nature Research journals

Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone

In macrophages, the accumulation of cholesteryl esters synthesized by the activated acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT1) results in the foam cell formation, a hallmark of early atherosclerotic lesions. In this study, with the treatment of a glucocorticoid hormone dexamethasone (Dex), lipid staining results clearly showed the large accumulation of lipid droplets...

Repair of osteonecrosis of the femoral head

BackgroundOsteonecrosis of the femoral head (ONFH) is a common joint disease and a major cause of morbidity.ObjectiveIn this study Cervi cornus Colla (CCC) deproteinized bone scaffolds were designed and three dimensional (3D)-printed for the repair of ONFH in rats.Material and methodsThe CCC-deproteinized bone scaffolds were 3D-printed using polycaprolactone mixed with the CCC...

Mouse primordial germ cells produce cysts that partially fragment prior to meiosis

Lei Lei 0 Allan C. Spradling () 0 0 Howard Hughes Medical Institute Research Laboratories, Department of Embryology, Carnegie Institution of Washington , 3520 San Martin Drive, Baltimore, MD 21218

The Expression Patterns and Associated Clinical Parameters of Human Endogenous Retrovirus-H Long Terminal Repeat-Associating Protein 2 and Transmembrane and Immunoglobulin Domain Containing 2 in Oral Squamous Cell Carcinoma

Squamous Cell Carcinoma Yao Xiao,1 Hao Li,1 Lei-Lei Yang,1 Liang Mao,1 Cong-Cong Wu,1 Wen-Feng Zhang,2 and Zhi-Jun Sun1,2 1The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST