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Search: authors:"Lempainen, Johanna"

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Class II HLA Genotype Association With First-Phase Insulin Response Is Explained by Islet Autoantibodies

A declining first-phase insulin response (FPIR) is characteristic of the disease process leading to clinical type 1 diabetes. It is not known whether reduced FPIR depends on class II human leukocyte antigen (HLA) genotype, islet autoimmunity, or both.