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43 papers found.
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β2-microglobulin induces depressive- and anxiety-like behaviors in rat

Tang. Data curation: Dan Zeng, Yi-Li Yi, Yi-Yun Tang. Formal analysis: Ping Zhang, Dan Zeng, Wei Zou, Chun-Yan Wang. Funding acquisition: Ping Zhang, Wei Zou. Investigation: Ping Zhang, Dan Zeng, Xiao ... -Qing Tang. Methodology: Dan Zeng, Yi-Li Yi, Xue-Feng Yang. Project administration: Xue-Feng Yang, Xiao-Qing Tang. Resources: Ping Zhang, Dan Zeng, Xue-Feng Yang, Xiao-Qing Tang. Supervision: Xiao-Qing

An evolutionary classifier for steel surface defects with small sample set

Nowadays, surface defect detection systems for steel strip have replaced traditional artificial inspection systems, and automatic defect detection systems offer good performance when the sample set is large and the model is stable. However, the trained model does work well when a new production line is initiated with different equipment, processes, or detection devices. These...

Identifying protein complex by integrating characteristic of core-attachment into dynamic PPI network

International Cooperation Project of Hubei Province (No. 2014BHE0017), and the National Key Research and Development Program of China (SQ2017YFSF090207). Author Contributions Conceptualization: Li Yi. Formal ... analysis: Li Yi. Investigation: Li Yi. Methodology: Li Yi. Funding acquisition: Xingpeng Jiang, Tingting He, Wei Xie, Po Hu, Xiaohua Hu. Project administration: Xianjun Shen, Xingpeng Jiang, Xiaohua Hu

Numerical scheme and dynamic analysis for variable-order fractional van der Pol model of nonlinear economic cycle

Considering the fact that the memory in economic series changes with dynamic economic environment, this paper is devoted to the proposal of a variable-order fractional van der Pol model (VOFVDPM), where the order of the derivative is replaced by a time-dependent function. A numeric scheme for this model is designed by the Adams-Bashforth-Moulton method. The dynamic behaviors of...

Comparative analysis of fecal microbial communities in cattle and Bactrian camels

Bactrian camels may have a unique gastrointestinal (GI) microbiome because of their distinctive digestive systems, unique eating habits and extreme living conditions. However, understanding of the microbial communities in the Bactrian camel GI tract is still limited. In this study, microbial communities were investigated by comparative analyses of 16S rRNA hypervariable region V4...

Mining Temporal Protein Complex Based on the Dynamic PIN Weighted with Connected Affinity and Gene Co-Expression

The identification of temporal protein complexes would make great contribution to our knowledge of the dynamic organization characteristics in protein interaction networks (PINs). Recent studies have focused on integrating gene expression data into static PIN to construct dynamic PIN which reveals the dynamic evolutionary procedure of protein interactions, but they fail in...

△-Convergence analysis of improved Kuhfittig iterative for asymptotically nonexpansive nonself-mappings in W-hyperbolic spaces

Throughout this paper, we introduce a class of asymptotically nonexpansive nonself-mapping and modify the classical Kuhfittig iteration algorithm in the general setup of hyperbolic space. Also, △-convergence results are obtained under a limit condition. The results presented in the paper extend various results in the existing literature.

Surface Immobilization of Human Arginase-1 with an Engineered Ice Nucleation Protein Display System in E. coli

Ice nucleation protein (INP) is frequently used as a surface anchor for protein display in gram-negative bacteria. Here, MalE and TorA signal peptides, and three charged polypeptides, 6×Lys, 6×Glu and 6×Asp, were anchored to the N-terminus of truncated INP (InaK-N) to improve its surface display efficiency for human Arginase1 (ARG1). Our results indicated that the TorA signal...

Strong convergence theorems of the Halpern-Mann’s mixed iteration for a totally quasi-ϕ-asymptotically nonexpansive nonself multi-valued mapping in Banach spaces

spaces Liu Hong Bo 0 Li Yi 0 0 School of Science, Southwest University of Science and Technology , Mianyang, Sichuan 621010 , P.R. China In this paper, we introduce a class of totally quasi-φ

Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis

Cardiovascular diseases are the leading cause of death of death in Taiwan. Atherosclerosis can lead to serious problems, including heart attack, stroke, or even death. Coronary heart disease (CHD) occurs when plaque builds up in the coronary arteries to cause the ischemic heart disease which will enhance myocardial remodeling and also induce myocardial hypoxia. High density...

Dynamic identifying protein functional modules based on adaptive density modularity in protein-protein interaction networks

Background The identification of protein functional modules would be a great aid in furthering our knowledge of the principles of cellular organization. Most existing algorithms for identifying protein functional modules have a common defect -- once a protein node is assigned to a functional module, there is no chance to move the protein to the other functional modules during the...

Strong convergence theorems for a countable family of totally quasi-ϕ-asymptotically nonexpansive nonself mappings in Banach spaces with applications

In this paper, we introduce a class of totally quasi-ϕ-asymptotically nonexpansive nonself mappings and study the strong convergence under a limit condition only in the framework of Banach spaces. Meanwhile, our results are applied to study the approximation problem of a solution to a system of equilibrium problems. The results presented in the paper improve and extend the...

Crystal Structure and Identification of Two Key Amino Acids Involved in AI-2 Production and Biofilm Formation in Streptococcus suis LuxS

Streptococcus suis has emerged as an important zoonotic pathogen that causes meningitis, arthritis, septicemia and even sudden death in pigs and humans. Quorum sensing is the signaling network for cell-to-cell communication that bacterial cells can use to monitor their own population density through production and exchange of signal molecules. S-Ribosylhomocysteinase (LuxS) is...

Identification and characterization of a Streptococcus equi ssp. zooepidemicus immunogenic GroEL protein involved in biofilm formation

Streptococcus equi ssp. zooepidemicus (S. equi spp. zooepidemicus) is an opportunistic pathogen that causes major economic losses in the swine industry in China and is also a threat for human health. Biofilm formation by this bacterium has been previously reported. In this study, we used an immunoproteomic approach to search for immunogenic proteins expressed by biofilm-grown S...

Role of Myeloma-Derived MIF in Myeloma Cell Adhesion to Bone Marrow and Chemotherapy Response

Background: Multiple myeloma (MM) remains an incurable cancer characterized by accumulation of malignant plasma cells in the bone marrow (BM). The mechanism underlying MM homing to BM is poorly elucidated.

High-level expression of human arginase I in Pichia pastoris and its immobilization on chitosan to produce L-ornithine

Background L-ornithine (L-Orn), is an intermediate metabolite in the urea cycle that plays a significant role in humans. L-Orn can be obtained from the catalysis of L-arginine (L-Arg) by arginase. The Pichia pastoris expression system offers the possibility of generating a large amount of recombinant protein. The immobilized enzyme technology can overcome the difficulties in...

PALB2 mutations in breast cancer patients from a multi-ethnic region in northwest China

Background Germline mutations in PALB2 gene make a small contribution to heritable breast cancer susceptibility. A recent report has revealed that women with mutations in the PALB2 gene were more than nine times as likely to develop breast cancer compared to those without. The aim of this study is to understand the status of PALB2 mutations among Chinese high-risk breast cancer...

Development of a nanoparticle-assisted PCR (nanoPCR) assay for detection of mink enteritis virus (MEV) and genetic characterization of the NS1 gene in four Chinese MEV strains

Background Mink enteritis virus (MEV) causes mink viral enteritis, an acute and highly contagious disease whose symptoms include violent diarrhea, and which is characterized by high morbidity and mortality. Nanoparticle-assisted polymerase chain reaction (nanoPCR) is a recently developed technique for the rapid detection of bacterial and viral DNA. Here we describe a novel...

Cruciferous vegetable consumption and the risk of pancreatic cancer: a meta-analysis

Background Previous studies regarding the association between cruciferous vegetable intake and pancreatic cancer risk have reported inconsistent results. We conducted a meta-analysis to demonstrate the potential association between them. Methods A systematic literature search of papers was conducted in March 2014 using PubMed, EMBASE, and Web of Science, and the references of the...