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14 papers found.
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Fuzzy rule-based systems for recognition-intensive classification in granular computing context

In traditional machine learning, classification is typically undertaken in the way of discriminative learning using probabilistic approaches, i.e. learning a classifier that discriminates one class from other classes. The above learning strategy is mainly due to the assumption that different classes are mutually exclusive and each instance is clear-cut. However, the above...

Impact of plateau pikas (Ochotona curzoniae) on soil properties and nitrous oxide fluxes on the Qinghai-Tibetan Plateau

: Yan Zhou, Shengwu Jiao, Xinwei Zhu, Li Zhang. Formal analysis: Yan Zhou, Shengwu Jiao, Xinwei Zhu, Li Zhang. Funding acquisition: Guangchun Lei. Investigation: Yan Zhou, Shengwu Jiao, Nana Li

Accuracy of glomerular filtration rate equations for chronic kidney disease patients at the G3a stage: a single-center cross-sectional study

Background Kidney disease improving global outcomes provided a new classification for chronic kidney disease (CKD) by subdividing the G3 stage into G3a and G3b stages based on glomerular filtration rate (GFR) in 2012. Currently, a few methods are used to evaluate GFR, including measured GFR (mGFR) and estimated GFR (eGFR). One of the mGFR was 99mTc-DTPA scintigraphy method and...

An evaluation of boreal summer intra-seasonal oscillation simulated by BCC_AGCM2.2

The intra-seasonal oscillation (ISO) is a prominent feature of the East Asia summer monsoon. The Beijing Climate Center model is one of the IPCC models participating in the Coupled Model Inter-comparison Project (CMIP) 3 and CMIP5 experiments. This paper presents a systematic evaluation of ISO simulated by the Beijing Climate Center atmospheric general circulation model version 2...

The prognostic significance of DAPK1 in bladder cancer

Bladder cancer is one of the leading causes of cancer-related death in men, however, there was only limited effective treatment for invasive bladder cancer. DAPK1 has been shown to play important role in apoptosis and autophagy to suppress cancer progression. Previous results have shown that DAPK1 promoter was hypermethylated in the majority of bladder cancer specimens, however...

Hepatitis E Virus Produced from Cell Culture Has a Lipid Envelope

The absence of a productive cell culture system hampered detailed analysis of the structure and protein composition of the hepatitis E virion. In this study, hepatitis E virus from a robust HEV cell culture system and from the feces of infected monkeys at the peak of virus excretion was purified by ultra-centrifugation. The common feature of the two samples after...

Effectiveness of additional follow-up telephone counseling in a smoking cessation clinic in Beijing and predictors of quitting among Chinese male smokers

Background No previous studies have investigated whether additional telephone follow-up counseling sessions after face-to-face counseling can increase quitting in China, and whether this strategy is feasible and effective for promoting smoking cessation is still unclear. Methods A non-randomized controlled study was conducted in Beijing. We compared the quit rates of one group...

puma 3.0: improved uncertainty propagation methods for gene and transcript expression analysis

Background Microarrays have been a popular tool for gene expression profiling at genome-scale for over a decade due to the low cost, short turn-around time, excellent quantitative accuracy and ease of data generation. The Bioconductor package puma incorporates a suite of analysis methods for determining uncertainties from Affymetrix GeneChip data and propagating these...

Regulation of MicroRNA-155 in Atherosclerotic Inflammatory Responses by Targeting MAP3K10

Aims Accumulating evidence suggest that numerous microRNAs (miRNAs) play important roles in cell proliferation, apoptosis, and differentiation, as well as various diseases that accompany inflammatory responses. Inflammation is known to be a major contributor to atherogenesis. Previous studies provide promising evidence in support of the role of miRNAs in cardiovascular disease...

Fusion to chicken C3d enhances the immunogenicity of the M2 protein of avian influenza virus

Background Current vaccines to avian influenzae virus (AIV), a highly contagious disease of birds, need to be constantly updated due to the high level of variation in the target antigens. Therefore, a vaccine that could induce broad cross protection against AIV is required. The M2 membrane protein is structurally conserved amongst AIV subtypes but tends in induce a poor immune...

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode

Background Shuanglong formula (SLF), a Chinese medicine composed of panax ginseng and salvia miltiorrhiza exhibited significant effect in the treatment of myocardial infarction (MI) in clinical. Because of the complex nature and lack of stringent quality control, it's difficult to explain the action mechanism of SLF. Method In this study, we present a "system to system" (S2S...

Expression of particulate-form of Japanese encephalitis virus envelope protein in a stably transfected Drosophila cell line

Background Japanese encephalitis virus (JEV), a member of the family Flaviviridae, is an important mosquito-borne human pathogen. Its envelope glycoprotein (E) is the major determinant of the pathogenicity and host immune responses. In the present study, we explored the feasibility of producing recombinant JEV E protein in the virus-free Drosophila expression system. Results The...

Attitudes Toward Consumption and Conservation of Tigers in China

A heated debate has recently emerged between tiger farmers and conservationists about the potential consequences of lifting the ban on trade in farmed tiger products in China. This debate has caused unfounded speculation about the extent of the potential market for tiger products. To fill this knowledge gap, we surveyed 1880 residents from a total of six Chinese cities to...

High quality copy number and genotype data from FFPE samples using Molecular Inversion Probe (MIP) microarrays

Background A major challenge facing DNA copy number (CN) studies of tumors is that most banked samples with extensive clinical follow-up information are Formalin-Fixed Paraffin Embedded (FFPE). DNA from FFPE samples generally underperforms or suffers high failure rates compared to fresh frozen samples because of DNA degradation and cross-linking during FFPE fixation and...