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Search: authors:"Li Zhang"

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The formation of perovskite multiple quantum well structures for high performance light-emitting diodes

, Nanjing, 211816, ChinaYan Sun, Li Zhang, Nana Wang, Shuting Zhang, Yu Cao, Yanfeng Miao, Mengmeng Xu, Hao Zhang, Hai Li, Chang Yi, Jianpu Wang & Wei HuangShaanxi Institute of Flexible Electronics (SIFE ... ), Northwestern Polytechnical University (NPU), 127 West Youyi Road, Xi’an, 710072, Shaanxi, ChinaWei Huang AuthorsSearch for Yan Sun in:Nature Research journals • PubMed • Google Scholar Search for Li Zhang

Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing

RBM15, an RNA binding protein, determines cell-fate specification of many tissues including blood. We demonstrate that RBM15 is methylated by protein arginine methyltransferase 1 (PRMT1) at residue R578 leading to its degradation via ubiquitylation by an E3 ligase (CNOT4). Overexpression of PRMT1 in acute megakaryocytic leukemia cell lines blocks megakaryocyte terminal...

The value of oral contrast ultrasonography in the diagnosis of gastric cancer in elderly patients

This study aims to investigate the value of oral contrast ultrasonography (OCUS) in the diagnosis of gastric cancer in elderly patients. OCUS data obtained from patients ≥ 60 years old were retrospectively analyzed and compared with gastroscopy results. Among the 12,716 subjects examined by OCUS, 5021 subjects were ≥ 60 years old, which accounted for 39.48% (5021/12,716...

Localized primary gastrointestinal diffuse large B cell lymphoma received a surgical approach: an analysis of prognostic factors and comparison of staging systems in 101 patients from a single institution

Background Diffuse large B cell lymphoma (DLBCL) represents the most common histological subtype of primary gastrointestinal lymphoma and is a heterogeneous group of disease. Prognostic characterization of individual patients is an essential prerequisite for a proper risk-based therapeutic choice. Methods Clinical and pathological prognostic factors were identified, and...

Evaluation of the benefit of using blue dye in addition to indocyanine green fluorescence for sentinel lymph node biopsy in patients with breast cancer

Near infrared-guided indocyanine green (ICG) fluorescence has vast potential for guiding sentinel lymph node biopsy (SLNB) in patients with breast cancer. The purpose of this study was to evaluate any additional clinical benefit for SLNB when blue dye is used in combination with ICG. Between November of 2009 and September of 2013, 86 patients diagnosed with breast cancer were...

Evaluation of the benefit of using blue dye in addition to indocyanine green fluorescence for sentinel lymph node biopsy in patients with breast cancer

Background Near infrared-guided indocyanine green (ICG) fluorescence has vast potential for guiding sentinel lymph node biopsy (SLNB) in patients with breast cancer. The purpose of this study was to evaluate any additional clinical benefit for SLNB when blue dye is used in combination with ICG. Methods Between November of 2009 and September of 2013, 86 patients diagnosed with...

Case report: locoregional (perineum and inguinal) recurrence after treatment of rectal cancer by low anterior resection

Rong Zhao 0 Li Zhang 1 0 Department of Colorectal Surgery, Tianjin Union Medicine Center , 190 Jieyuan Road, Hongqiao District, 300121 Tianjin , China 1 Department of Pathology, Tianjin Union

Immunization with a suicidal DNA vaccine expressing the E glycoprotein protects ducklings against duck Tembusu virus

Duck Tembusu virus (DTMUV), a pathogenic flavivirus, emerged in China since 2010 and causing huge economic loss in the Chinese poultry industry. Although several vaccines have been reported to control DTMUV disease, few effective vaccines are available and new outbreaks were continuously reported. Thus, it is urgently to develop a new effective vaccine for prevention of this...

MEK/ERK signaling pathway is required for enterovirus 71 replication in immature dendritic cells

Background The mitogen-activated protein kinase kinase/extracellular-signal-regulated kinase (MEK/ERK) signaling pathway is involved in viral life cycle. However, the effect of MEK/ERK pathway in enterovirus 71(EV71)-infected immature dendritic cells (iDCs) is still unclear. Methods Human peripheral blood mononuclear cells (PBMCs) were isolated and induced to generate iDCs...

Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China

Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoides) and a giant panda (Ailuropoda melanoleuca) in China. Phylogenetic analysis of the partial...

Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from giant panda and raccoon dogs in China

Background Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic Canidae. In this study, we sequenced and phylogenetic analyses of the hemagglutinin (H) genes from eight canine distemper virus (CDV) isolates obtained from seven raccoon dogs (Nyctereutes procyonoides) and a giant panda (Ailuropoda melanoleuca) in China. Results Phylogenetic...

Comparison of the efficacy of tenofovir and adefovir in the treatment of chronic hepatitis B: A Systematic Review

Chronic viral hepatitis B remains a global public health concern. Currently, several drugs, such as tenofovir and adefovir, are recommended for treatment of patients with chronic hepatitis B. tenofovir is a nucleoside analog with selective activity against hepatitis b virus and has been shown to be more potent in vitro than adefovir. But the results of trials comparing tenofovir...

Vaccination with dengue virus-like particles induces humoral and cellular immune responses in mice

Background The incidence of dengue, an infectious disease caused by dengue virus (DENV), has dramatically increased around the world in recent decades and is becoming a severe public health threat. However, there is currently no specific treatment for dengue fever, and licensed vaccine against dengue is not available. Vaccination with virus-like particles (VLPs) has shown...

Fusion to chicken C3d enhances the immunogenicity of the M2 protein of avian influenza virus

Background Current vaccines to avian influenzae virus (AIV), a highly contagious disease of birds, need to be constantly updated due to the high level of variation in the target antigens. Therefore, a vaccine that could induce broad cross protection against AIV is required. The M2 membrane protein is structurally conserved amongst AIV subtypes but tends in induce a poor immune...

Replication and transcription of human papillomavirus type 58 genome in Saccharomyces cerevisiae

Background To establish a convenient system for the study of human papillomavirus (HPV), we inserted a Saccharomyces cerevisiae selectable marker, Ura, into HPV58 genome and transformed it into yeast. Results HPV58 genome could replicate extrachromosomally in yeast, with transcription of its early and late genes. However, with mutation of the viral E2 gene, HPV58 genome lost its...

Expression of particulate-form of Japanese encephalitis virus envelope protein in a stably transfected Drosophila cell line

Background Japanese encephalitis virus (JEV), a member of the family Flaviviridae, is an important mosquito-borne human pathogen. Its envelope glycoprotein (E) is the major determinant of the pathogenicity and host immune responses. In the present study, we explored the feasibility of producing recombinant JEV E protein in the virus-free Drosophila expression system. Results The...

Stage-specific developmental gene expression of goat preimplantation embryos produced in vitro

Single preimplantation embryo mRNA differential display was used to study the gene expression of 2-cell,4-cell, and 8-16-cell stage goat embryos produced in vitro, and 16 different stage specific bands in total were screened. In these specific bands, 5 were in 2-cell stage, 4 were in 4-cell stage, and 7 were in 8-16-cell stage, respectively. The sequencing and alignment results...

Polar Optical Phonon Modes and Fröhlich Electron-Phonon Interaction Hamiltonians in Coaxial Cylindrical Quantum Cables

By using the dielectric continuum approximation, the polar optical phonon modes of coaxial cylindrical quantum cables with arbitrary layer-number were studied. In order to describe the vibrating of the longitudinal-optical (LO) phonons, a set of legitimate eigenfunctions for LO phonon modes are constructed and adopted. In order to deal with the interface optical (IO) phonon modes...

Full polar optical phonon states and dispersive spectra of a wurtzite GaN/AlN rectangular quantum wire

Within the framework of the dielectric continuum model and Loudon's uniaxial crystal model, the full polar optical phonon modes including the quasi-confined (QC) modes, the propagating (PR) modes, the half-space (HS) modes, and the interface optical (IO) modes in a quasi-one-dimensional (Q1D) wurtzite rectangular quantum wire (QWR) structure are deduced and analyzed. The...

Vibration spectra of polar mixing optical phonon states and Fröhlich electron-phonon coupling behaviors in a wurtzite ZnO quantum dot

Based on the dielectric continuum model and Loudon's uniaxial crystal model, the interface-optical-propagating (IO-PR) mixing phonon states of a quasi-zero-dimensional (Q0D) wurtzite cylindrical quantum dot (QD) are investigated. It is found that there are two types of IO-PR mixing phonon modes, i.e. r-IO/z-PR mixing modes and the z-IO/r-PR mixing modes coexisting in Q0D wurtzite...