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Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

Awakawa in:Nature Research journals • PubMed • Google Scholar Search for Takuma Fujioka in:Nature Research journals • PubMed • Google Scholar Search for Lihan Zhang in:Nature Research journals • PubMed ... genetic tools. Author information AffiliationsGraduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, JapanTakayoshi Awakawa, Takuma Fujioka, Lihan

NME2 Reduces Proliferation, Migration and Invasion of Gastric Cancer Cells to Limit Metastasis

Gastric cancer is one of the most common malignancies and has a high rate of metastasis. We hypothesize that NME2 (Nucleoside Diphosphate Kinase 2), which has previously been considered as an anti-metastatic gene, plays a role in the invasiveness of gastric cancer cells. Using a tissue chip technology and immunohistochemistry, we demonstrated that NME2 expression was associated...