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40 papers found.
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Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro Su Hu,1,* Li Xu,1,2,* Lihua Li,1 Dongdong Luo,1 Hailin Zhao,1 Dan Li,1 Biao Peng1 1Department of ... , People's republic of china PowerdbyTCPDF(ww.tcpdf.org) lihua li 1 Dongdong luo 1 hailin Zhao 1 Dan li 1 Background: Glioma is one of the most common malignancies of the central nervous system in adults. The

Electrophilic fatty acid nitroalkenes regulate Nrf2 and NF-κB signaling:A medicinal chemistry investigation of structure-function relationships

) Lihua Li Sonia R. Salvatore Francisco J. Schopfer Bruce A. Freeman Fatty acid nitroalkene derivatives (NO2-FA) activate Nrf2-regulated antioxidant gene expression and inhibit NF-?B-dependent cytokine

Multi-functional bismuth-doped bioglasses: combining bioactivity and photothermal response for bone tumor treatment and tissue repair

Treatment of large bone defects derived from bone tumor surgery is typically performed in multiple separate operations, such as hyperthermia to extinguish residual malignant cells or implanting bioactive materials to initiate apatite remineralization for tissue repair; it is very challenging to combine these functions into a material. Herein, we report the first photothermal (PT...

Exploring the Mediating Effect of E-social Capital Between Community Members Interaction and Consumer Engagement

This article explored the effect of instrumental interaction and relational interaction on consumer engagement (community engagement and brand engagement) among community members. The mediating effect of E-social capital was investigated as well. The research results showed that: both instrumental interaction and interpersonal interaction promote the formation of E-social capital...

Heterogeneity of Diffusion-Weighted Imaging in Tumours and the Surrounding Stroma for Prediction of Ki-67 Proliferation Status in Breast Cancer

Zhang in:Nature Research journals • PubMed • Google Scholar Search for Lihua Li in:Nature Research journals • PubMed • Google Scholar Contributions M.F. and L.L. conceived the main idea and ... tables. Competing Interests The authors declare that they have no competing interests. Corresponding author Correspondence to Lihua Li. Electronic supplementary material Supplementary Figure 1

Variability of Ionospheric TEC and the Performance of the IRI-2012 Model at the BJFS Station, China

We studied variation characteristics of ionospheric total electron contents (TEC) and performance of the International Reference Ionosphere (IRI)-2012 model in predicting TEC at the BJFS (Beijing Fangshan station), China. Diurnal and seasonal variations were analyzed with TEC data derived from dual-frequency global positioning system (GPS) observations along with the solar...

Radiomic analysis reveals DCE-MRI features for prediction of molecular subtypes of breast cancer

The purpose of this study was to investigate the role of features derived from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and to incorporated clinical information to predict the molecular subtypes of breast cancer. In particular, 60 breast cancers with the following four molecular subtypes were analyzed: luminal A, luminal B, human epidermal growth...

Sum Rate Analysis of MU-MIMO with a 3D MIMO Base Station Exploiting Elevation Features

Although the three-dimensional (3D) channel model considering the elevation factor has been used to analyze the performance of multiuser multiple-input multiple-output (MU-MIMO) systems, less attention is paid to the effect of the elevation variation. In this paper, we elaborate the sum rate of MU-MIMO systems with a 3D base station (BS) exploiting different elevations. To...

Sum Rate Analysis of MU-MIMO with a 3D MIMO Base Station Exploiting Elevation Features

Although the three-dimensional (3D) channel model considering the elevation factor has been used to analyze the performance of multiuser multiple-input multiple-output (MU-MIMO) systems, less attention is paid to the effect of the elevation variation. In this paper, we elaborate the sum rate of MU-MIMO systems with a 3D base station (BS) exploiting different elevations. To...

Investigating the Temporal Patterns within and between Intrinsic Connectivity Networks under Eyes-Open and Eyes-Closed Resting States: A Dynamical Functional Connectivity Study Based on Phase Synchronization

The brain active patterns were organized differently under resting states of eyes open (EO) and eyes closed (EC). The altered voxel-wise and regional-wise resting state active patterns under EO/EC were found by static analysis. More importantly, dynamical spontaneous functional connectivity has been observed in the resting brain. To the best of our knowledge, the dynamical...

The role of plasma exchange in treating post-transplant focal segmental glomerulosclerosis: A systematic review and meta-analysis of 77 case-reports and case-series

Background Evidence on the role of plasma exchange for treating recurrent post-transplant focal segmental glomerulosclerosis (FSGS) comes largely from individual cases and uncontrolled series. We conducted a systematic review and meta-analysis to estimate the remission rate after treatment with plasma exchange, and to determine if remission varied with patient or treatment...

Aquaporin-1 Deficiency Protects Against Myocardial Infarction by Reducing Both Edema and Apoptosis in Mice

, PR ChinaTonghui Ma AuthorsSearch for Lihua Li in:Nature Research journals • PubMed • Google ScholarSearch for Zhiyong Weng in:Nature Research journals • PubMed • Google ScholarSearch for Chenjuan Yao ... , materials and analysis tools. L.H.L. wrote the paper. Competing interests The authors declare no competing financial interests. Corresponding authors Correspondence to Lihua Li or Tonghui Ma. Rights and

Effects of Self-Assembled Monolayers with Different Chemical Groups on Ovarian Cancer Cell Line Behavior In Vitro

In addition to serving as a physical support, the extracellular matrix (ECM) actively influences cell behavior. However, the definitive effects of different chemical structures present in the ECM on cell behavior remain obscure. The current study aimed to investigate the effects of different chemical structures present in the ECM on cellular physiology using the ovarian cancer...

CML/RAGE signal induces calcification cascade in diabetes

Objective Vascular calcification is a significant predictor of coronary heart disease events, stroke, and lower-limb amputation. Advanced glycation end-products (AGEs) play a key role in the development of vascular calcification. However, the role of Nε-carboxymethyl-lysine (CML), a major active ingredient of heterogeneous AGEs, in the development of atherosclerotic calcification...

Isoalantolactone Enhances the Radiosensitivity of UMSCC-10A Cells via Specific Inhibition of Erk1/2 Phosphorylation

National Natural Science Foundation of China (31571184, recipient: Lihua Li) and Aohongboze Graduate Sci-tech Innovation Foundation, the President Fund of Liaoning Medical University (recipient: Yonggan Fan

Visual sensing of Hg2+ using unmodified Au@Ag core–shell nanoparticles

In this work, we have developed a novel visual Hg2+ sensor in aqueous solution using unmodified Au@Ag core–shell nanoparticles at room temperature, based on a redox reaction between Ag-shell and Hg2+. The prepared Au@Ag core–shell nanoparticles exhibited good monodispersity. In the presence of Hg2+, Hg2+ was reduced into Hg (0) by Ag-shell, and deposited on the surface of Au-core...

The Oncogenic Response to MiR-335 Is Associated with Cell Surface Expression of Membrane-Type 1 Matrix Metalloproteinase (MT1-MMP) Activity

MicroRNA miR-335 has been reported to have both tumor suppressor and oncogenic activities. In order to determine possible tissue and cell type differences in response to miR-335, we examined the effect of miR-335 on cell expression of MT1-MMP, a proteinase commonly expressed in tumors and associated with cell proliferation and migration. miR-335 increased cell surface expression...

Molecular Characterization and Viral Origin of the 2015 Dengue Outbreak in Xishuangbanna, Yunnan, China

A total of 1067 serum samples were collected from febrile patients in Xishuangbanna, Yunnan, 2015. Of these, 852 cases were confirmed to be dengue NS1-positive. 76 structural protein genes were sequenced through RT-PCR based on the viral RNAs extracted from serum samples. Phylogenetic analysis revealed that all strains were classified as cosmopolitan genotype of DENV-2. After...

Hybrid extragradient method for generalized mixed equilibrium problems and fixed point problems in Hilbert space

In this paper, we introduce iterative schemes based on the extragradient method for finding a common element of the set of solutions of a generalized mixed equilibrium problem and the set of fixed points of a nonexpansive mapping, and the set of solutions of a variational inequality problem for inverse strongly monotone mapping. We obtain some strong convergence theorems for the...

Candida albicans Carriage in Children with Severe Early Childhood Caries (S-ECC) and Maternal Relatedness

Introduction Candida albicans has been detected together with Streptococcus mutans in high numbers in plaque-biofilm from children with early childhood caries (ECC). The goal of this study was to examine the C. albicans carriage in children with severe early childhood caries (S-ECC) and the maternal relatedness. Methods Subjects in this pilot cross-sectional study were recruited...