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Emotional distress and dysfunctional illness perception are associated with low mental and physical quality of life in Chinese breast cancer patients

To evaluate the relationship between quality of life (QOL) and physical as well as psychological variables in Chinese breast cancer patients. This multicenter cross-sectional study enrolled 254 Chinese breast cancer patients in different stages and treatment phases. They answered standard instruments assessing QOL (EORTC), somatic symptom severity (PHQ-15), depression (PHQ-9...

Emotional distress and dysfunctional illness perception are associated with low mental and physical quality of life in Chinese breast cancer patients

To evaluate the relationship between quality of life (QOL) and physical as well as psychological variables in Chinese breast cancer patients. This multicenter cross-sectional study enrolled 254 Chinese breast cancer patients in different stages and treatment phases. They answered standard instruments assessing QOL (EORTC), somatic symptom severity (PHQ-15), depression (PHQ-9...

Biomarkers of Dietary Polyphenols in Cancer Studies: Current Evidence and Beyond

Polyphenols, commonly contained in fruits and vegetables, have long been associated with a protective role against multiple diseases and adverse health effects. Generally, in vitro and animal experiments have provided strong positive evidence, whereas evidence from in vivo and human epidemiological studies is not strong enough. Most epidemiological studies to date use food...

Biomarkers of Dietary Polyphenols in Cancer Studies: Current Evidence and Beyond

Polyphenols, commonly contained in fruits and vegetables, have long been associated with a protective role against multiple diseases and adverse health effects. Generally, in vitro and animal experiments have provided strong positive evidence, whereas evidence from in vivo and human epidemiological studies is not strong enough. Most epidemiological studies to date use food...

Hospitalized Patients at High Risk for Obstructive Sleep Apnea Have More Rapid Response System Events and Intervention Is Associated with Reduced Events

Sharma has an unrestricted research grant from RESMED corp. This does not alter the authors' adherence to PLOS ONE policies on sharing data and materials. Lili Tang is statistician for the Thomas Jefferson

Integrated analysis of promoter mutation, methylation and expression of AKT1 gene in Chinese breast cancer patients

Background As downstream mediators of PI3K /PTEN /AKT /mTORC1 pathway, the AKT isoforms play critical roles in tumorgenesis. Although the pleiotropic effects of AKT1 in breast cancer have been reported, the genetic and epigenetic characteristics of AKT1 promoter region in breast cancer remains to be identified. In this study we aimed to investigate the promoter mutation spectrum...

Elevational Patterns of Plant Richness in the Taibai Mountain, China

© 2014 Lili Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

Elevational Patterns of Plant Richness in the Taibai Mountain, China

© 2014 Lili Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

MiR-99a Antitumor Activity in Human Breast Cancer Cells through Targeting of mTOR Expression

MicroRNAs (miRNAs) play an important role in human tumorigenesis as oncogenes or tumor suppressors. miR-99a has been reported as a tumor suppressor gene in various cancers in humans. However, only limited information about the function of miR-99a in human breast cancers is available. Here we investigated the expression of miR-99a in breast cancer tissue specimens and its...

Genotype combination contributes to psoriasis: An exhaustive algorithm perspective

. Resources: Chao Yang, Lei Ye, Leilei Wen, Yuyan Cheng, Lili Tang, Caihong Zhu, Zhengwei Zhu, Wenjun Wang. Writing ± original draft: Jinfa Dou. Writing ± review & editing: Liangdan Sun, Xiaodong Zheng

Heme acts through the Bach1b/Nrf2a-MafK pathway to regulate exocrine peptidase precursor genes in porphyric zebrafish

Using a zebrafish model of hepatoerythropoietic porphyria (HEP), we identify a previously unknown mechanism underlying heme-mediated regulation of exocrine zymogens. Zebrafish bach1b, nrf2a and mafK are all expressed in the zebrafish exocrine pancreas. Overexpression of bach1b or knockdown of nrf2a result in the downregulation of the expression of the exocrine zymogens, whereas...

MicroRNA-486 as a Biomarker for Early Diagnosis and Recurrence of Non-Small Cell Lung Cancer

. Zhongmin Guo is the employee of Changzhou GoPath Diagnostic Laboratory Co. Ltd and GoPath Laboratories LLC in Buffalo Grove , IL, USA. Wanshuai Li, Qi Zhang, Lili Tang, Xiaoping Liu - Peripheral blood

GmFT2a and GmFT5a Redundantly and Differentially Regulate Flowering through Interaction with and Upregulation of the bZIP Transcription Factor GmFDL19 in Soybean

FLOWERING LOCUS T (FT) is the key flowering integrator in Arabidopsis (Arabidopsis thaliana), and its homologs encode florigens in many plant species regardless of their photoperiodic response. Two FT homologs, GmFT2a and GmFT5a, are involved in photoperiod-regulated flowering and coordinately control flowering in soybean. However, the molecular and genetic understanding of the...

Erratum to: Psychosocial oncology in China — Challenges and opportunities

June Erratum to: Psychosocial oncology in China Lili Tang 1 Barry D. Bultz 0 0 Department of Psychosocial Resources, Tom Baker Cancer Centre , Alberta Cancer Board , Canada 1 Key Laboratory of

Antibody-Mediated “Universal” Osteoclast Targeting Platform using Calcitonin as a Model Drug

Madhuri Newa Krishna Hari Bhandari Lili Tang Rohit Kalvapalle Mavanur Suresh Michael R. Doschak 0 ) Faculty of Pharmacy & Pharmaceutical Sciences, University of Alberta Edmonton , Alberta T6G 2N8

Allelic Combinations of Soybean Maturity Loci E1, E2, E3 and E4 Result in Diversity of Maturity and Adaptation to Different Latitudes

Soybean cultivars are extremely diverse in time to flowering and maturation as a result of various photoperiod sensitivities. The underlying molecular genetic mechanism is not fully clear, however, four maturity loci E1, E2, E3 and E4 have been molecularly identified. In this report, cultivars were selected with various photoperiod sensitivities from different ecological zones...

Mitigation of Oxidative Damage by Green Tea Polyphenols and Tai Chi Exercise in Postmenopausal Women with Osteopenia

Background Osteoporosis is a degenerative bone disease predominantly in postmenopausal women. Green tea polyphenols (GTP) and Tai Chi (TC) have been shown to be beneficial on human bone health. This study examined the efficacy of GTP and TC on mitigation of oxidative damage in postmenopausal women with osteopenia. Methods A 6-month randomized and placebo-controlled clinical trial...

Oncogenic HER2 fusions in gastric cancer

Background Genetic amplification of HER2 drives tumorigenesis and cancer progression in a subset of patients with gastric cancer (GC), and treatment with trastuzumab, a humanized HER2-neutralizing antibody, improves the overall survival rate of HER2-positive patients. However, a considerable portion of the patients does not respond to trastuzumab and the molecular mechanisms...

Expression of wild soybean WRKY20 in Arabidopsis enhances drought tolerance and regulates ABA signalling

The WRKY-type transcription factors are involved in plant development and stress responses, but how the regulation of stress tolerance is related to plant development is largely unknown. GsWRKY20 was initially identified as a stress response gene using large-scale Glycine soja microarrays. Quantitative reverse transcription–PCR (qRT–PCR) showed that the expression of this gene...