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52 papers found.
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Band-inverted gaps in InAs/GaSb and GaSb/InAs core-shell nanowires

The [111]-oriented InAs/GaSb and GaSb/InAs core-shell nanowires have been studied by the 8 × 8 Luttinger-Kohn Hamiltonian to search for non-vanishing fundamental gaps between inverted electron and hole bands. We focus on the variations of the band-inverted fundamental gap, the hybridization gap, and the effective gap with the core radius and shell thickness of the nanowires. The...

H2AX facilitates classical non-homologous end joining at the expense of limited nucleotide loss at repair junctions

Phosphorylated histone H2AX, termed ‘γH2AX’, mediates the chromatin response to DNA double strand breaks (DSBs) in mammalian cells. H2AX deficiency increases the numbers of unrepaired DSBs and translocations, which are partly associated with defects in non-homologous end joining (NHEJ) and contributing to genomic instability in cancer. However, the role of γH2AX in NHEJ of...

Pregnancy increases stroke risk up to 1 year postpartum and reduces long-term risk

Background: The incidence of stroke in pregnant women is low but trending upward. There are few studies of the topic in women of Asian ethnicity.

Arabidopsis ERF1 Mediates Cross-Talk between Ethylene and Auxin Biosynthesis during Primary Root Elongation by Regulating ASA1 Expression

The gaseous phytohormone ethylene participates in the regulation of root growth and development in Arabidopsis. It is known that root growth inhibition by ethylene involves auxin, which is partially mediated by the action of the WEAK ETHYLENE INSENSITIVE2/ANTHRANILATE SYNTHASE α1 (WEI2/ASA1), encoding a rate-limiting enzyme in tryptophan (Trp) biosynthesis, from which auxin is...

Social Capital and Health-Protective Behavior Intentions in an Influenza Pandemic

Health-protective behaviors, such as receiving a vaccine, wearing a face mask, and washing hands frequently, can reduce the risk of contracting influenza. However, little is known about how social capital may influence health-protective behavior in the general population. This study examined whether each of the social capital dimensions (bonding, bridging, and linking...

ATF2 predicts poor prognosis and promotes malignant phenotypes in renal cell carcinoma

Background Activating transcription factor 2 (ATF2) is a basic helix-loop-helix transcription factor, which has been shown to participate in the pathobiology of numerous cancers. However, the role of ATF2 in renal cell carcinoma (RCC) remains unclear. Methods ATF2 knockdown and overexpression studies were performed in RCC cells to evaluate changes in cell viability, cell cycle...

Evolving pneumococcal serotypes and sequence types in relation to high antibiotic stress and conditional pneumococcal immunization

, Chang Gung Memorial Hospital, Taoyuan, 333, TaiwanCheng-Hsun Chiu AuthorsSearch for Lin-Hui Su in:Nature Research journals • PubMed • Google ScholarSearch for An-Jing Kuo in:Nature Research journals

Nasal Carriage of Methicillin-Resistant Staphylococcus aureus among Pediatricians in Taiwan

BackgroundHealth care workers (HCWs) are at the interface between hospitals and communities. The survey for methicillin-resistant Staphylococcus aureus (MRSA) carriage among HCWs has mostly been conducted to investigate outbreaks or endemics. Community-associated MRSA are prevalent among children in Taiwan. We conducted this study to better understand the carriage rate of MRSA...

The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer

, Bing Tian & Yue-Jin HuaInstitute of Zhejiang Cancer Research, Zhejiang Cancer Hospital, Hangzhou, 310022, ChinaZhi-Guo Zheng, Mao-Wei Ni, Lin-Hui Gu & Wei Chen AuthorsSearch for Zhi-Guo Zheng in:Nature ... -Li Xu in:Nature Research journals • PubMed • Google ScholarSearch for Mao-Wei Ni in:Nature Research journals • PubMed • Google ScholarSearch for Lin-Hui Gu in:Nature Research journals • PubMed • Google

Galectin-12 enhances inflammation by promoting M1 polarization of macrophages and reduces insulin sensitivity in adipocytes

Galectin-12 is a member of an animal lectin family with affinity for β-galactosides and containing consensus amino acid sequences. Here, we found that galectin-12 was expressed in macrophages and thus aimed to determine how galectin-12 affects inflammation and macrophage polarization and activation. The ablation of galectin-12 did not affect bone marrow cells to differentiate...

Protocol-directed insulin infusion sliding scales improve perioperative hyperglycaemia in critical care

Perioperative hyperglycaemia is associated with poor outcomes in patients undergoing cardiac surgery. Frequent postoperative hyperglycaemia in cardiac surgery patients has led to the initiation of an insulin infusion sliding scale for quality improvement. A systematic review was conducted to determine whether a protocol-directed insulin infusion sliding scale is as safe and...

Protocol-directed insulin infusion sliding scales improve perioperative hyperglycaemia in critical care

Perioperative hyperglycaemia is associated with poor outcomes in patients undergoing cardiac surgery. Frequent postoperative hyperglycaemia in cardiac surgery patients has led to the initiation of an insulin infusion sliding scale for quality improvement. A systematic review was conducted to determine whether a protocol-directed insulin infusion sliding scale is as safe and...

Antisideslip and Antirollover Safety Speed Controller Design for Vehicle on Curved Road

When the drivers cannot be aware of the existing of forthcoming curved roads and fail to regulate their safety speeds accordingly, sideslip or rollover may occur with high probability. The antisideslip and antirollover control of vehicle on curved road in automatic highway systems is studied. The safety speed warning system is set before entering the curved road firstly. The...

Antisideslip and Antirollover Safety Speed Controller Design for Vehicle on Curved Road

When the drivers cannot be aware of the existing of forthcoming curved roads and fail to regulate their safety speeds accordingly, sideslip or rollover may occur with high probability. The antisideslip and antirollover control of vehicle on curved road in automatic highway systems is studied. The safety speed warning system is set before entering the curved road firstly. The...

Macro-management of microRNAs in cell cycle progression of tumor cells and its implications in anti-cancer therapy

Jiao Tong University School of Medicine, Shanghai 200032, ChinaLin-hui Liang & Xiang-huo He AuthorsSearch for Lin-hui Liang in:Nature Research journals • PubMed • Google ScholarSearch for Xiang-huo He

MADS-Box Transcription Factor AGL21 Regulates Lateral Root Development and Responds to Multiple External and Physiological Signals

Plant root system morphology is dramatically influenced by various environmental cues. The adaptation of root system architecture to environmental constraints, which mostly depends on the formation and growth of lateral roots, is an important agronomic trait. Lateral root development is regulated by the external signals coordinating closely with intrinsic signaling pathways. MADS...

Incidence, Duration, Persistence, and Factors Associated With High-risk Anal Human Papillomavirus Persistence Among HIV-negative Men Who Have Sex With Men: A Multinational Study

Background. Given high rates of anal disease, we investigated the natural history of high-risk anal human papillomavirus (HPV) among a multinational group of men who have sex with men (MSM) aged 18–64 years.

Maternal Hypoxia Increases the Susceptibility of Adult Rat Male Offspring to High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease

Exposure to an adverse intrauterine environment increases the risk for adult metabolic syndrome. However, the influence of prenatal hypoxia on the risk of fatty liver disease in offspring is unclear. The purpose of the present study was to evaluate the role of reduced fetal oxygen on the development and severity of high-fat (HF) diet-induced nonalcoholic fatty liver disease...