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The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells

The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells Hua Jiang,1,* Jingjing Fan,2,* Lin Cheng,1 Pan Hu,1 Renbin Liu1 1Department of Breast and

Effect of casting methods on microstructure and mechanical properties of ZM5 space flight magnesium alloy

AuthorsAuthors and affiliations Xu-liang ZhangGuo-kang YuWen-bing ZouYan-shuo JiYing-zhuo LiuJia-lin Cheng Research & Development First Online: 13 December 2018 5 Downloads Abstract The counter

A Novel Kinematic Parameters Identification Method for Articulated Arm Coordinate Measuring Machines Using Repeatability and Scaling Factor

June 2018; Published 15 July 2018 Academic Editor: Salvatore Strano Copyright © 2018 Lin Cheng et al. This is an open access article distributed under the Creative Commons Attribution License, which

A Novel Kinematic Parameters Identification Method for Articulated Arm Coordinate Measuring Machines Using Repeatability and Scaling Factor

June 2018; Published 15 July 2018 Academic Editor: Salvatore Strano Copyright © 2018 Lin Cheng et al. This is an open access article distributed under the Creative Commons Attribution License, which

Transforming growth factor beta 1 mediates the low-frequency vertical vibration enhanced production of tenomodulin and type I collagen in rat Achilles tendon

Lin, Chau-Zen Wang. Investigation: Yi-Hsiung Lin, Yan-Hsiung Wang. Methodology: Tsung-Lin Cheng. Project administration: Ming-Long Yeh. Resources: Chau-Zen Wang. Software: Ming-Long Yeh. Supervision ... : Chia-Hsin Chen, Chung-Hwan Chen. Validation: Yan-Hsiung Wang, Tsung-Lin Cheng. Writing ? original draft: Yi-Hsiung Lin. Writing ? review & editing: Chau-Zen Wang. 16 / 19 17 / 19 18 / 19 1. Cardinale

Conversion of human adipose-derived stem cells into functional and expandable endothelial-like cells for cell-based therapies

BackgroundIschemic vascular diseases are the major cause of death worldwide. In recent years, endothelial cell (EC)-based approaches to vascular regeneration are increasingly viable strategies for treating ischemic diseases, but their applications are challenged by the difficulties in their efficient generation and stable maintenance. Here, we show an alternative protocol that...

Long non-coding RNA tagging and expression manipulation via CRISPR/Cas9-mediated targeted insertion

the future. FOOTNOTES We thank Yuefang Zhang and Shifang Shan for their help in experiments. We also thank members of the entire Qiu lab for their help and suggestions. Tian-Lin Cheng is supported by ... The Knowledge Innovation Program of CAS 2014KIP205, Shanghai Sailing Program 15YF1414200, and NSFC #31600826. Zilong Qiu is supported by NSFC #91432111, #31625013. Tian-Lin Cheng and Zilong Qiu

Focus on Mesenchymal Stem Cell-Derived Exosomes: Opportunities and Challenges in Cell-Free Therapy

: Changwon Park Copyright © 2017 Lin Cheng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in

A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies

Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. Emerging evidence shows that exosomes are mediators of metastasis in tumour cells, stromal cells and the...

A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies

Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. Emerging evidence shows that exosomes are mediators of metastasis in tumour cells, stromal cells and the...

A comprehensive overview of exosomes in ovarian cancer: emerging biomarkers and therapeutic strategies

Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. Emerging evidence shows that exosomes are mediators of metastasis in tumour cells, stromal cells and the...

Identification of Common Genes Refers to Colorectal Carcinogenesis with Paired Cancer and Noncancer Samples

Colorectal cancer is a malignant tumor which harmed human beings’ health. The aim of this study was to explore common biomarkers associated with colorectal carcinogenesis in paired cancer and noncancer samples. At first, fifty-nine pairs of colorectal cancer and noncancer samples from three gene expression datasets were collected and analyzed. Then, 181 upregulation and 282...

Cocktail of chemical compounds robustly promoting cell reprogramming protects liver against acute injury

epithelial; TGF-β, transforming growth factor beta; VPA, valproic acid. COMPLIANCE WITH ETHICS GUIDELINES Lin Cheng and Yuewen Tang declare that they have no conflict of interest. All institutional and

Interleukin-35 on B cell and T cell induction and regulation

Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transduction of IL-35, the regulation effect of IL-35 on B cells and T cells as well as the adoptive transfer of IL-35+ regulatory B cells (Breg), therapeutic prospects of...

Production of high stellar-mass primordial black holes in trapped inflation

Trapped inflation has been proposed to provide a successful inflation with a steep potential. We discuss the formation of primordial black holes in the trapped inflationary scenario. We show that primordial black holes are naturally produced during inflation with a steep trapping potential. In particular, we have given a recipe for an inflaton potential with which particle...

Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury

and Jonatan Olafsson for help with RGC counts. Author Contributions Conceptualization: Dong Feng Chen. Data curation: Lin Cheng, Lucy J. Wong, Naihong Yan, Richard C. Han, Honghua Yu, Chenying Guo ... , Khulan Batsuuri, Aniket Zinzuwadia, Ryan Guan, Kin-Sang Cho. Formal analysis: Lin Cheng, Lucy J. Wong, Naihong Yan, Richard C. Han, Khulan Batsuuri, Aniket Zinzuwadia, Ryan Guan, Kin-Sang Cho, Dong Feng

Evaluating turnaround times for early infant diagnosis samples in Kenya from 2011-2014: A retrospective analysis of HITSystem program data

Wexler, An-Lin Cheng, Brad Gautney, Sarah Finocchario-Kessler, Kathy Goggin, Samoel Khamadi. Project administration: Catherine Wexler, Brad Gautney, Sarah Finocchario-Kessler, . Supervision: Brad Gautney ... , Sarah Finocchario-Kessler, Kathy Goggin, Samoel Khamadi, . Visualization: An-Lin Cheng. Writing ± original draft: Catherine Wexler. Writing ± review & editing: Catherine Wexler, An-Lin Cheng, Brad

The Role of Initial Credit Distribution Scheme in Managing Network Mobility and Maximizing Reserve Capacity: Considering Traveler’s Cognitive Illusion

, Southeast University, Nanjing 210096, China Received 21 December 2015; Accepted 28 February 2016 Academic Editor: Gabriella Bretti Copyright © 2016 Fei Han and Lin Cheng. This is an open access article

The Role of Initial Credit Distribution Scheme in Managing Network Mobility and Maximizing Reserve Capacity: Considering Traveler’s Cognitive Illusion

, Southeast University, Nanjing 210096, China Received 21 December 2015; Accepted 28 February 2016 Academic Editor: Gabriella Bretti Copyright © 2016 Fei Han and Lin Cheng. This is an open access article

Boundedly Rational User Equilibrium with Restricted Unused Routes

A boundedly rational user equilibrium model with restricted unused routes (R-BRUE) considering the restrictions of both used route cost and unused route cost is proposed. The proposed model hypothesizes that for each OD pair no traveler can reduce his/her travel time by an indifference band by unilaterally changing route. Meanwhile, no route is unutilized if its travel time is...