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The association between outpatient follow-up visits and all-cause non-elective 30-day readmissions: A retrospective observational cohort study

Contributions Conceptualization: Tim Arnold. Data curation: Liping Tong. Formal analysis: Liping Tong. Methodology: Liping Tong, Jie Yang. Project administration: Tim Arnold. Resources: Tim Arnold, Xinyong ... Tian, Cole Erdmann. Supervision: Tina Esposito. Writing ? original draft: Liping Tong. Writing ? review & editing: Liping Tong, Tim Arnold, Jie Yang, Xinyong Tian, Cole Erdmann, Tina Esposito. 11 / 12

Association of polymorphisms in the aldosterone-regulated sodium reabsorption pathway with blood pressure among Hispanics

Background Whereas genome-wide association study (GWAS) has proven to be an important tool for discovery of variants influencing many human diseases and traits, unfortunately its performance has not been much of all-around success for some complex conditions, for example, hypertension. Because some of the existing effective pharmacotherapeutic agents act by targeting known...

Comparison of predictive modeling approaches for 30-day all-cause non-elective readmission risk

Background This paper explores the importance of electronic medical records (EMR) for predicting 30-day all-cause non-elective readmission risk of patients and presents a comparison of prediction performance of commonly used methods. Methods The data are extracted from eight Advocate Health Care hospitals. Index admissions are excluded from the cohort if they are observation...

Detection of epidermal growth factor receptor mutation in plasma as a biomarker in Chinese patients with early-stage non-small cell lung cancer

Wang,1 YongAn Zhou,1 HongGang Liu,1 LiPing Tong,1 XiaoFei Li,1 XiaoLong Yan11Department of Thoracic Surgery, Tangdu Hospital, 2Department of Ultrasound, Xijing Hospital, 3Department of Ophthalmology

The social patterning of risk factors for noncommunicable diseases in five countries: evidence from the modeling the epidemiologic transition study (METS)

Stringhini 0 3 Terrence E. Forrester 2 Jacob Plange-Rhule 1 Estelle V. Lambert 7 Bharathi Viswanathan 6 Walter Riesen 5 Wolfgang Korte 5 Naomi Levitt 4 Liping Tong 8 Lara R. Dugas 8 David Shoham 8 Ramon A

Comparison of SNP-based and gene-based association studies in detecting rare variants using unrelated individuals

We compare the SNP-based and gene-based association studies using 697 unrelated individuals. The Benjamini-Hochberg procedure was applied to control the false discovery rate for all the multiple comparisons. We use a linear model for the single-nucleotide polymorphism (SNP) based association study. For the gene-based study, we consider three methods. The first one is based on a...

DRUGS System Enhancing Adherence of Chinese Surgeons to Antibiotic Use Guidelines during Perioperative Period

Objective Irrational use of antimicrobial agents for preventing postoperative SSIs is a common phenomenon in China, which results in more bacterial resistance, higher hospital infection rates, extra costs of antimicrobial agents. The aim of the study is to evaluate the effect of Drug Rational Usage Guidelines System (DRUGS) on the surgeon's prescription behavior of antimicrobial...

An Actor-Based Model of Social Network Influence on Adolescent Body Size, Screen Time, and Playing Sports

Recent studies suggest that obesity may be “contagious” between individuals in social networks. Social contagion (influence), however, may not be identifiable using traditional statistical approaches because they cannot distinguish contagion from homophily (the propensity for individuals to select friends who are similar to themselves) or from shared environmental influences. In...

Genetic Background of Patients from a University Medical Center in Manhattan: Implications for Personalized Medicine

Background The rapid progress currently being made in genomic science has created interest in potential clinical applications; however, formal translational research has been limited thus far. Studies of population genetics have demonstrated substantial variation in allele frequencies and haplotype structure at loci of medical relevance and the genetic background of patient...

Comparison of multipoint linkage analyses for quantitative traits in the CEPH data: parametric LOD scores, variance components LOD scores, and Bayes factors

We performed multipoint linkage analyses with multiple programs and models for several gene expression traits in the Centre d'Etude du Polymorphisme Humain families. All analyses provided consistent results for both peak location and shape. Variance-components (VC) analysis gave wider peaks and Bayes factors gave fewer peaks. Among programs from the MORGAN package, lm_multiple...