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Dose-dependent protective effect of nicotine in a murine model of viral myocarditis induced by coxsackievirus B3

Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaZhao Jing-Lin, Chen Guang-Yi, Liu Li, Zhou De-Pu & Li Yue-Chun AuthorsSearch for Ge Li-Sha in:Nature Research journals • PubMed • Google ... ScholarSearch for Zhao Jing-Lin in:Nature Research journals • PubMed • Google ScholarSearch for Chen Guang-Yi in:Nature Research journals • PubMed • Google ScholarSearch for Liu Li in:Nature Research journals

Role of arachidonic acid in hyposmotic membrane stretch-induced increase in calcium-activated potassium currents in gastric myocytes

Aim:To study effects of arachidonic acid (AA) and its metabolites on the hyposmotic membrane stretch-induced increase in calcium-activated potassium currents (IKCa) in gastric myocytes.Methods:Membrane currents were recorded by using a conventional whole cell patch-clamp technique in gastric myocytes isolated with collagenase.Results:Hyposmotic membrane stretch and AA increased...