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Stochastic Extinction in an SIRS Epidemic Model Incorporating Media Coverage

, Wenzhou 325035, China Received 2 December 2013; Accepted 12 December 2013 Academic Editor: Kaifa Wang Copyright © 2013 Liyan Wang et al. This is an open access article distributed under the Creative

Characterization of a Novel Anti-DR5 Monoclonal Antibody WD1 with the Potential to Induce Tumor Cell Apoptosis

TNF-related apoptosis-inducing ligand (TRAIL) is a TNF family member capable of inducing apoptosis. Death receptor 5 (DR 5) is a key receptor of TRAIL and plays an important role in TRAIL-induced apoptosis. To prepare monoclonal antibodies (mAbs) against DR5, cDNA encoding soluble DR5 (sDR5) was firstly amplified by reverse transcriptase-polymerase chain reaction (RT-PCR) with...