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Search: authors:"Mahomed-Yunus S Moosa"

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Integrating hypertension screening at the time of voluntary HIV testing among adults in South Africa

Krows, Sabina Govere, Connie Celum. Formal analysis: Paul K. Drain, Ting Hong, Anjum Hajat. Funding acquisition: Paul K. Drain, Hilary Thulare, Mahomed Yunus S. Moosa, Connie Celum. Investigation: Paul ... K. Drain. Methodology: Paul K. Drain, Mahomed Yunus S. Moosa. 12 / 15 Project administration: Meighan Krows, Sabina Govere, Hilary Thulare, Ingrid Bassett. Supervision: Hilary Thulare, Connie Celum

Rapid Urine LAM Testing Improves Diagnosis of Expectorated Smear-Negative Pulmonary Tuberculosis in an HIV-endemic Region

Research journals • PubMed • Google ScholarSearch for Faieza Sahid in:Nature Research journals • PubMed • Google ScholarSearch for Mahomed-Yunus S. Moosa in:Nature Research journals • PubMed • Google Scholar

A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection

-Yunus S Moosa 2 Paul K Drain 3 4 0 University of Maryland School of Medicine , 655 W. Baltimore Street, Baltimore, MD 21201 , USA 1 Department of Virology, National Health Laboratory Service, Inkosi

Co-Infection with Mycobacterium tuberculosis Impairs HIV-Specific CD8+ and CD4+ T Cell Functionality

The ability of antigen-specific T cells to simultaneously produce multiple cytokines is thought to correlate with the functional capacity and efficacy of T cells. These ‘polyfunctional’ T cells have been associated with control of HIV. We aimed to assess the impact of co-infection with Mycobacterium tuberculosis (MTB) on HIV-specific CD8+ and CD4+ T cell function. We assessed T...

Adjunctive Tests for Diagnosis of Tuberculosis: Serology, ELISPOT for Site-Specific Lymphocytes, Urinary Lipoarabinomannan, String Test, and Fine Needle Aspiration

The diagnostic gold standard for active tuberculosis (TB) is the detection of Mycobacterium tuberculosis (MTB) by culture or molecular methods. However, despite its limited sensitivity, sputum smear microscopy is still the mainstay of TB diagnosis in resource-limited settings. Consequently, diagnosis of smear-negative pulmonary and extrapulmonary TB remains challenging in such...

Defining Immune Reconstitution Inflammatory Syndrome: Evaluation of Expert Opinion versus 2 Case Definitions in a South African Cohort

Background.There is no validated case definition for human immunodeficiency virus-associated immune reconstitution inflammatory syndrome (IRIS). We measured the level of agreement of 2 published case definitions (hereafter referred to as CD1 and CD2) with expert opinion in a prospective cohort of patients who were starting antiretroviral therapy in South Africa. Methods.A total...

Cutaneous Extensively Drug-Resistant Tuberculosis

A 48-year-old immunocompetent man without known exposure to tuberculosis had a > 10-year history of recurrent skin lesions. Cutaneous tuberculosis without any current or past history of pulmonary tuberculosis was diagnosed. Culture of biopsy specimens showed the organism to be resistant to multiple first-line and second-line agents. The patient had a broad, vigorous CD4-specific...

HIV Online Provider Education (HOPE): The Internet as a Tool for Training in HIV Medicine

Human immunodeficiency virus (HIV) treatment programs in resource-limited areas are expanding rapidly. Providing training and education to health care providers in these programs is a major challenge. We have employed Internet-based conferencing technology to conduct interactive case-based training conferences with health care professionals in Africa, Asia, and the Caribbean...