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The Indiana University Cognitive Health Outcomes Investigation of the Comparative Effectiveness of dementia screening (CHOICE) study: study protocol for a randomized controlled trial

Fowler fowlernr@upmc.edu 0 Amanda Harrawood Amie Frame Anthony J Perkins Sujuan Gao Christopher M Callahan Greg A Sachs Dustin D French Malaz A Boustani 0 Department of Medicine, University of Pittsburgh

Medication adherence and tolerability of Alzheimer’s disease medications: study protocol for a randomized controlled trial

Background The class of acetylcholinesterase inhibitors (ChEI), including donepezil, rivastigmine, and galantamine, have similar efficacy profiles in patients with mild to moderate Alzheimer’s disease (AD). However, few studies have evaluated adherence to these agents. We sought to prospectively capture the rates and reasons for nonadherence to ChEI and determine factors...

Alzheimer’s disease multiple intervention trial (ADMIT): study protocol for a randomized controlled clinical trial

Background Given the current lack of disease-modifying therapies, it is important to explore new models of longitudinal care for older adults with dementia that focus on improving quality of life and delaying functional decline. In a previous clinical trial, we demonstrated that collaborative care for Alzheimer’s disease reduces patients’ neuropsychiatric symptoms as well as...

Improving delirium care in the intensive care unit: The design of a pragmatic study

Buckley Regg Sing Jason Tricker Mohammad Zawahiri Malaz A Boustani 0 Department of Pharmacy Practice, Purdue University School of Pharmacy , West Lafayette, IN , USA Background: Delirium prevalence in the