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6 papers found.
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MLPA as a complementary tool for diagnosis of chromosome 21 aberrations in childhood BCP-ALL

Chromosome 21 abnormalities are the most frequent genetic findings in childhood B cell precursor acute lymphoblastic leukemia (BCP-ALL) cases. Majority of patients are effectively diagnosed with fluorescence in situ hybridization (FISH) and karyotyping; however, some cases may require additional tools to be used. Bone marrow samples of 373 childhood BCP-ALL patients were tested...

The Expression of the SLIT–ROBO Family in Adult Patients with Acute Myeloid Leukemia

IntroductionSLIT–ROBO is a ligand–receptor family of neuronal guidance cues that has been involved in pathological and physiological angiogenesis. SLIT–ROBO expression is altered in many tumours. However, no data exist about the role of the whole family in acute myelogenous myeloid leukemia (AML).PurposeHerein, we assessed the expression of all SLIT–ROBO family in bone marrow (BM...

Intratumor heterogeneity and tissue distribution of KRAS mutation in non-small cell lung cancer: implications for detection of mutated KRAS oncogene in exhaled breath condensate

PurposeMutated KRAS oncogene in exhaled breath condensate (EBC) can be a genetic marker of non-small cell lung cancer (NSCLC). However, a possibility of inhomogeneous distribution in cancer tissue and intratumor heterogeneity of KRAS mutation may decrease its significance. We investigated a status of KRAS point mutation and its sequence at codon 12 in 51 NSCLC patients after...

MicroRNAs in regulation of triple-negative breast cancer progression

death from cancer among women, with age-standardized mortality rate of 12.9/100,000 worldwide (Ferlay et?al. 2014; Tao et?al. 2015) . Comprehensive gene Dominika Piasecka and Marcin Braun are the first

The Stricter the Better? The Relationship between Targeted HbA1c Values and Metabolic Control of Pediatric Type 1 Diabetes Mellitus

Copyright © 2016 Marcin Braun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ... Wojciech Fendler conceived this study. Marcin Braun, Bartlomiej Tomasik, and Ewa Wrona did the searches, selection of studies, data extraction, and statistical analysis. Wojciech Fendler contributed to

The Stricter the Better? The Relationship between Targeted HbA1c Values and Metabolic Control of Pediatric Type 1 Diabetes Mellitus

Copyright © 2016 Marcin Braun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ... Wojciech Fendler conceived this study. Marcin Braun, Bartlomiej Tomasik, and Ewa Wrona did the searches, selection of studies, data extraction, and statistical analysis. Wojciech Fendler contributed to