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Search: authors:"Marco Capobianco"

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High-Risk PML Patients Switching from Natalizumab to Alemtuzumab: an Observational Study

patients: MM, MC, MLR, MM, FS, AdS; Wrote the paper: SM. Disclosures. Simona Malucchi has received speaking honoraria and/or consultant fees from Biogen, Merck Serono, Novartis, Teva, and Genzyme. Marco ... Capobianco has received speaking honoraria and/or consultant fees from Biogen, Merck Serono, Novartis, Teva, Genzyme, and Almirall. Marianna Lo Re has received travel expenses from Biogen, Novartis, and Teva

Normative Values for Intertrial Variability of Motor Responses to Nerve Root and Transcranial Stimulation: A Condition for Follow-Up Studies in Individual Subjects

Objective Intertrial variability (ITV) of motor responses to peripheral (CMAP) and transcranial (MEP) stimulation prevents their use in follow-up studies. Our purpose was to develop strategies to reduce and measure CMAP and MEP ITV to guide long-term monitoring of conduction slowing and conduction failure of peripheral and central motor pathway in the individual patient. Methods...

Identifying responders and nonresponders to interferon therapy in multiple sclerosis

Identifying responders and nonresponders to interferon therapy in multiple sclerosis Luca Prosperini,1 Marco Capobianco,2 Costanza Giannì31Department of Neurology and Psychiatry, Sapienza University

Natalizumab Discontinuation and Treatment Strategies in Patients with Multiple Sclerosis (MS): A Retrospective Study from Two Italian MS Centers

Biogen, Novartis, and changes were made. Teva. Marco Capobianco has received speaking honoraria and/or consultant fees from Biogen, Merck-Serono, Novartis, Teva, Genzyme, and Almirall. Paolo Ragonese has

Peculiar Cytological Cerebrospinal Fluid Pattern in a Case of Encephalomyelitis During Anti-Tumor Necrosis Factor-α Therapy

work as a whole, and have given final approval for the version to be published. Conflict of interest. Yana Motuzova, Alessia Di Sapio, Marco Capobianco, Arianna Sala, Antonio Bertolotto declare no

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome

Background A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG-IgG). Objective To describe the epidemiological, clinical, radiological, cerebrospinal fluid (CSF), and electrophysiological features of a large cohort of MOG-IgG-positive patients with optic neuritis (ON...

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 1: Frequency, syndrome specificity, influence of disease activity, long-term course, association with AQP4-IgG, and origin

Background Antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) have been suggested to play a role in a subset of patients with neuromyelitis optica and related disorders. Objective To assess (i) the frequency of MOG-IgG in a large and predominantly Caucasian cohort of patients with optic neuritis (ON) and/or myelitis; (ii) the frequency of MOG-IgG among AQP4-IgG-positive...

Evaluation of a Multiparametric Immunofluorescence Assay for Standardization of Neuromyelitis Optica Serology

Background Neuromyelitis optica (NMO) is a severely disabling autoimmune disorder of the central nervous system, which predominantly affects the optic nerves and spinal cord. In a majority of cases, NMO is associated with antibodies to aquaporin-4 (AQP4) (termed NMO-IgG). Aims In this study, we evaluated a new multiparametric indirect immunofluorescence (IIF) assay for NMO...

Learning from Nature: Pregnancy Changes the Expression of Inflammation-Related Genes in Patients with Multiple Sclerosis

Background Pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood. Methodology We conducted a genome-wide transcription analysis in peripheral blood mononuclear cells (PBMCs) from 12 women (7 MS patients and 5 healthy controls) followed during...