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New strategy of controlled, stepwise release from novel MBioF and its potential application for drug delivery systems

Metal organic structures have gained recently an interest in many fields. Among them, metal–biomolecule framework materials with amino acids applied as organic linkers have attracted the growing attention. An application of tailored metal–biomolecule frameworks, easily decomposing in an acidic and/or reductive environment in a steerable way, is reported here. From these...

Stability of coordination polymers in water: state of the art and towards a methodology for nonporous materials

A mini review on the study concerning water stability of coordination polymers (CPs) is presented. Next, following the procedure proposed recently by Gelfand and Shimizu (Dalton Trans 45:3668–3678, 2016) the stability of three cysteine (Cys)—containing CPs is investigated. The stability of studied CPs decreases in the order: Zn(Cys)2 > Mg(Cys)2 > Ca(Cys)2 H2O. For the latter...

Comment on ‘‘Elucidating the binding efficacy of β-galactosidase on graphene by docking approach and its potential application in galacto-oligosaccharide production”

In a recent study, Satar et al. (Bioprocess Biosyst Eng 39:807–814, 2016) have reported “the synthesis and characterization of graphene for the immobilization of β-galactosidase for improved galacto-oligosaccharide (GOS) production”. There are several issues in this study that must be commented.

Controlling enzymatic activity by immobilization on graphene oxide

In this study, graphene oxide (GO) has been applied as a matrix for enzyme immobilization. The protein adsorption capacity of GO is much higher than of other large surface area carbonaceous materials. Its structure and physicochemical properties are reported beneficial also for enzymatic activity modifications. The experimental proof was done here that GO-based biocatalytic...

Hyperventilation with Maintenance of Isocapnia. An “Old New” Method in Carbon Monoxide Intoxication

Introduction Exposure to carbon monoxide (CO) is among the most common causes of acute and chronic poisonings worldwide. The crucial point of treatment of such acute poisonings is to eliminate CO from the body as fast as possible. There are currently two approaches to the management of the CO intoxication: hyperbaric oxygen therapy (HOT) and normobaric oxygen therapy (NOT). HOT...

Phenol adsorption on different nano-sized carbon materials: first comparative study

Carbon nanofibres and multi-branched carbon nanotubes are synthesized by using a new, proposed in this study method. The acid–base, adsorption and geometric properties of nanomaterials are characterised. Next we present first comparative adsorption and calorimetric studies of phenol uptake from aqueous solutions on mentioned nano-sized carbon materials and on nanotubes having...

The Chemistry of Bioconjugation in Nanoparticles-Based Drug Delivery System

Nanomedicine is, generally, the application of nanotechnology to medicine. The term nanomedicine includes monitoring, construction of novel drug delivery systems, and any possible future applications of nanotechnology and nanovaccinology. In this review, the most important ligand-nanocarrier and drug-nanocarrier bioconjugations are described. The detailed characterizations of...

Conscious Changes of Carbon Nanotubes Cytotoxicity by Manipulation with Selected Nanofactors

We discuss eight major challenges in the field of carbon nanomaterial toxicity. Generally, we pick up some of them, and the most important challenge is searching of the qualitative relationships between nanofactors and cytotoxicity. This is important since it can provide the possibility of conscious changes of carbon nanotubes cytotoxicity by manipulation with selected...

Porosity of closed carbon nanotubes compressed using hydraulic pressure

Experimental data of nitrogen adsorption (T = 77.3 K) from gaseous phase measured on commercial closed carbon nanotubes are presented. Additionally, we show the results of N2 adsorption on compressed (using hydraulic press) CNTs. In order to explain the experimental observations the results of GCMC simulations of N2 adsorption on isolated or bundled multi-walled closed nanotubes...

Carbon nanotubes as potential material for drug delivery—experiment and simulation

We discuss the factors influencing the properties of new drug delivery system, composed of carbon nanotubes and analgesic antipyretic drug—paracetamol. Basing on experimental data it is shown, that by a simple manipulation with the heating time at the stage of system preparation, one can easily change the rate of the drug delivery. Moreover, this rate can be changed in a very...

Simple model of adsorption on external surface of carbon nanotubes—a new analytical approach basing on molecular simulation data

Nitrogen adsorption on carbon nanotubes is wide- ly studied because nitrogen adsorption isotherm measurement is a standard method applied for porosity characterization. A further reason is that carbon nanotubes are potential adsorbents for separation of nitrogen from oxygen in air. The study presented here describes the results of GCMC simulations of nitrogen (three site model...