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HPV16 E6/E7 expression in circulating tumor cells in oropharyngeal squamous cell cancers: A pilot study

, Euthymios Kirodimos, Evangelos Giotakis, Pavlos Maragoudakis. Software: Margaritis Avgeris. Supervision: Amanda Psyrri. Validation: Areti Strati, Christos Kroupis, Ioannis Pateras, Vassilis Gorgoulis ... . Writing ? original draft: Panagiota Economopoulou. Writing ? review & editing: Panagiota Economopoulou, George Koutsodontis, Margaritis Avgeris, Amanda Psyrri. 10 / 12 11 / 12 1. Nelson HH , Pawlita M

Uncovering the clinical utility of miR-143, miR-145 and miR-224 for predicting the survival of bladder cancer patients following treatment

Accurate prognosis is a key factor in establishing optimal therapeutic decisions; yet in the case of bladder cancer (BlCa) current prognostic indicators cannot ensure optimal disease management. Here, we aimed to evaluate the previously unexplored clinical potential of the urological cancer-related miR-145, miR-143 and miR-224 in BlCa. A total of 279 bladder tissue specimens were...

Down-regulation of kallikrein-related peptidase 5 (KLK5) expression in breast cancer patients: a biomarker for the differential diagnosis of breast lesions

Background Kallikrein-related peptidase 5 (KLK5) is a secreted trypsin-like protease of the KLK family, encoded by the KLK5 gene. KLK5 has been found to cleave various extracellular matrix components, as well as to activate several other KLK proteases, triggering the stimulation of tissue microenvironment proteolytic cascades. Material and Methods KLK5 expression levels were...