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Fitness and food environments around junior high schools in Taiwan and their association with body composition: Gender differences for recreational, reading, food and beverage exposures

Chiang, Lin-Yuan Huang, Meei-Shyuan Lee, Mark L. Wahlqvist. Data curation: Lin-Yuan Huang. Formal analysis: Lin-Yuan Huang. Methodology: Lin-Yuan Huang, Hui-Chen Tsou, Mark L. Wahlqvist. Project ... administration: Mark L. Wahlqvist. Supervision: Po-Huang Chiang, Meei-Shyuan Lee, Mark L. Wahlqvist. Validation: Po-Huang Chiang, Lin-Yuan Huang, Mark L. Wahlqvist. Visualization: Hui-Chen Tsou. Writing

Effect of n-3 polyunsaturated fatty acid on gene expression of the critical enzymes involved in homocysteine metabolism

Background Previous studies showed that plasma n-3 polyunsaturated fatty acid (PUFA) was negatively associated with plasma homocysteine (Hcy). Objective We investigated the regulatory effect of n-3 PUFA on mRNA expression of the critical genes encoding the enzymes involved in Hcy metabolism. Methods HepG2 cells were treated with docosahexaenoic acid (DHA), eicosapentaenoic acid...

Spending on vegetable and fruit consumption could reduce all-cause mortality among older adults

Background Few studies have evaluated the linkage between food cost and mortality among older adults. This study considers the hypothesis that greater food expenditure in general, and particularly on more nutritious plant and animal-derived foods, decreases mortality in older adults. Methods This study uses the 1999–2000 Elderly Nutrition and Health Survey in Taiwan and follows...

Increased risk of affective disorders in type 2 diabetes is minimized by sulfonylurea and metformin combination: a population-based cohort study

Background To confirm whether type 2 diabetes (T2DM) is an affective disorder (AD) precursor, and to establish possible effects of oral anti-hyperglycemic agents (OAAs). Methods A representative cohort of 800,000 subjects was obtained from the Taiwanese National Health Insurance database on 1 January 2000. Those with consistent data (n = 762,753) were followed up between 1...

Age- and gender-specific population attributable risks of metabolic disorders on all-cause and cardiovascular mortality in Taiwan

Background The extent of attributable risks of metabolic syndrome (MetS) and its components on mortality remains unclear, especially with respect to age and gender. We aimed to assess the age- and gender-specific population attributable risks (PARs) for cardiovascular disease (CVD)-related mortality and all-cause mortality for public health planning. Methods A total of 2,092 men...

Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals

Background Metformin protection against cancer risk in Orientals is uncertain. We examined the possible metformin effect on total, esophageal, gastric, colorectal (CRC), hepatocellular (HCC) and pancreatic cancers in a Taiwanese cohort. Methods A representative sample of 800,000 was drawn from the Taiwanese National Health Insurance data of 2000. A cohort of 480,984 participants...

Poverty Increases Type 2 Diabetes Incidence and Inequality of Care Despite Universal Health Coverage

CHIH-CHENG HSU DRPH CHENG-HUA LEE DRPH MARK L. WAHLQVIST HSIAO-LING HUANG DRPH HSING-YI CHANG DRPH LIKWANG CHEN PHD SHU-FANG SHIH PHD SHYI-JANG SHIN PHD WEN-CHEN TSAI DRPH TED CHEN PHD CHI-TING HUANG

Gene expression profiling of breast cancer survivability by pooled cDNA microarray analysis using logistic regression, artificial neural networks and decision trees

Background Microarray technology can acquire information about thousands of genes simultaneously. We analyzed published breast cancer microarray databases to predict five-year recurrence and compared the performance of three data mining algorithms of artificial neural networks (ANN), decision trees (DT) and logistic regression (LR) and two composite models of DT-ANN and DT-LR...

Letter to the editor and reply

faithfully, Mark L. Wahlqvist, B. ivied. Sc., M.D. University of Uppsala Department of Geriatrics - Dear Sir, The concepts presented in the paper "The effectof insulin on the incorporation of sodium (l--i~C