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Erratum to: The OECD validation program of the H295R steroidogenesis assay: Phase 3. Final inter-laboratory validation study

, Germany 1 Department of Veterinary Biomedical Sciences and Toxicology Centre, University of Saskatchewan , Saskatoon, Saskatchewan , Canada 2 Markus Hecker 3 Office of Science Coordination & Policy, US

Endocrine disruptor screening: regulatory perspectives and needs

Markus Hecker 1 Henner Hollert henner.hollert@bio5.rwth-aachen 0 0 Department of Ecosystem Analysis, Institute for Environmental Research, RWTH Aachen University , Worringerweg 1, 52074 Aachen

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

Daniel L. Villeneuve 3 Doug Crump 0 Nata` lia Garcia-Reyero 2 Markus Hecker 5 Thomas H. Hutchinson 4 Carlie A. LaLone 3 jj Brigitte Landesmannjjj Teresa Lettierijjj Sharon Munnjjj Malgorzata

Adverse Outcome Pathway Development II: Best Practices

Daniel L. Villeneuve 3 Doug Crump 0 Nata` lia Garcia-Reyero 2 Markus Hecker 5 Thomas H. Hutchinson 4 Carlie A. LaLone 3 k Brigitte Landesmannjjj Teresa Lettierijjj Sharon Munnjjj Malgorzata

Contribution of Priority PAHs and POPs to Ah Receptor-Mediated Activities in Sediment Samples from the River Elbe Estuary, Germany

Jens C. Otte Steffen Keiter Christopher Fabender Eric B. Higley Paula Suares Rocha Markus Brinkmann Dierk-Steffen Wahrendorf Werner Manz Markus A. Wetzel Thomas Braunbeck John P. Giesy Markus Hecker

Hepatic P450 Enzyme Activity, Tissue Morphology and Histology of Mink (Mustela vison) Exposed to Polychlorinated Dibenzofurans

Dose- and time-dependent effects of environmentally relevant concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQ) of 2,3,7,8-tetrachlorodibenzofuran (TCDF), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF), or a mixture of these two congeners on hepatic P450 enzyme activity and tissue morphology, including jaw histology, of adult ranch mink were determined under...

Effects of Atrazine on CYP19 Gene Expression and Aromatase Activity in Testes and on Plasma Sex Steroid Concentrations of Male African Clawed Frogs (Xenopus laevis)

Some investigators have suggested that the triazine herbicide atrazine can cause demasculinization of male amphibians via upregulation of the enzyme aromatase. Male adult African clawed frogs (Xenopus laevis) were exposed to three nominal concentrations of atrazine (1, 25, or 250μg atrazine/l) for 36 days, and testicular aromatase activity and CYP19 gene expression, as well as...