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Search: authors:"Markus W. Löffler"

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Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma

variant Varns Non-synonymous somatic variant WES Whole exome sequencing WTlig Wild-type peptide corresponding to PNE with evidence on HLA ligandome level (HLA class I) Markus W. Löffler and Christopher ... Königsrainer, Markus W. Löffler, University Hospital of Tübingen, Department of General, Visceral and Transplant Surgery, Eberhard Karls University Tübingen, Tübingen, Germany; Hans-Georg Rammensee, Cécile

Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer

Nod-like receptors (NLRs) are important innate pattern recognition receptors and regulators of inflammation or play a role during development. We systematically analysed 41 non-synonymous single nucleotide polymorphisms (SNPs) in 21 NLR genes in a Czech discovery cohort of sporadic colorectal cancer (CRC) (1237 cases, 787 controls) for their association with CRC risk and survival...

Superficial Wound Swabbing: A novel method of sampling and processing wound fluid for subsequent immunoassay analysis in diabetic foot ulcerations

OBJECTIVE In diabetic foot ulcers, wound fluid inflammatory mediators have previously been proposed as surrogate markers for nonhealing. However, currently available wound fluid sampling techniques are not suitable for clinical practice due to low levels of exudate and a high logistical effort. The aim of this investigation was to assess 1) the technique of superficial wound...