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Defining the role of neutrophil-to-lymphocyte ratio in COPD: a systematic literature review

Defining the role of neutrophil-to-lymphocyte ratio in COPD: a systematic literature review Yuliana Pascual-González,1 Marta López-Sánchez,1 Jordi Dorca,1 Salud Santos1,2 1Department of Respiratory

Impact of acute exacerbations on platelet reactivity in chronic obstructive pulmonary disease patients

López-Sánchez,1 Gerard Roura,2 Joan Antoni Gómez-Hospital,2 Jordi Dorca,1 Angel Cequier,2 Salud Santos1,3 1Department of Pulmonary Medicine, Bellvitge University Hospital, IDIBELL, University of Barcelona ... . 6 4 . 9 5 . 7 3 y b / m o c . s s e r p e v o d . w w w / / : s p t t h .y lnodow rsnope PowerdbyTCPDF(ww.tcpdf.org) O r I g I n a l r e s e a r C h ana lucrecia Marcano 2 Marta lópez-sánchez 1 gerard

Vascular disease in COPD: Systemic and pulmonary expression of PARC (Pulmonary and Activation-Regulated Chemokine)

Introduction The role of Pulmonary and Activation-Regulated Chemokine (PARC) in the physiopathology of Chronic Obstructive Pulmonary Disease (COPD) is not fully understood. The aim of the present study is to analyze the expression of PARC in lung tissue and its relationship with the vascular remodeling of the systemic and pulmonary arteries of COPD subjects. Methods To achieve...

Systemic and Pulmonary Vascular Remodelling in Chronic Obstructive Pulmonary Disease

Background Chronic Obstructive Pulmonary Disease (COPD) is associated with subclinical systemic atherosclerosis and pulmonary vascular remodelling characterized by intimal hyperplasia and luminal narrowing. We aimed to determine differences in the intimal thickening of systemic and pulmonary arteries in COPD subjects and smokers. Secondary aims include comparisons with a non...

Treatment of patients with COPD and recurrent exacerbations: the role of infection and inflammation

Pomares,7 Marta López-Sánchez,1 Mariana Muñoz-Esquerre,1 Marc Miravitlles2,81Pneumology Department, Hospital Universitari de Bellvitge, Universidad de Barcelona, Bellvitge Biomedical Research Institute ... doses of ICS Pomares, Marta López-Sánchez, and Mariana Muñoz-Esquerre. over lower doses in COPD have been reported. The meeting was sponsored by GlaxoSmithKline. Conclusion Inflammatory mechanisms play

High Prevalence of Left Ventricle Diastolic Dysfunction in Severe COPD Associated with A Low Exercise Capacity: A Cross-Sectional Study

BackgroundA subclinical left ventricle diastolic dysfunction (LVDD) has been described in patients with chronic obstructive pulmonary disease (COPD). ObjectivesTo evaluate the prevalence of LVDD in stable severe COPD patients, to analyze its relationship with exercise capacity and to look for its possible causes (lung hyperinflation, ventricular interdependence or inflammatory...