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Integrated Co-Professional Evaluation? Converging Approaches to School Evaluation Across Frontiers

Education - Article 6 Integrated co-Professional Evaluation? Converging Approaches to School Evaluation across Frontiers Martin Brown Gerry McNamara Joe Ohara Shivaun O?Brien Cornelius Young DCU

Financial Literacy and Retirement Planning in Switzerland

Retirement Planning in Switzerland Creative Commons License This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License Cover Page Footnote Martin Brown is Full Professor of

SMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathway

Background While aberrant activation of the chromatin-remodeling SWI/SNF complexes has been associated with cancer development and progression, the role of each subunit in tumor cells is poorly defined. This study is aimed to characterize the role of SMARCE1/BAF57 in regulating metastasis of breast cancer cells. Methods Genetic approaches and chemical inhibitors were used to...

MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers

Introduction In breast cancer, distinct expression profiles of microRNAs (miRNAs) have been associated with molecular subgroups and clinicopathological characteristics, implicating a diagnostic and prognostic role of miRNAs. However, the biological functions of deregulated miRNAs in tumor progression are not yet completely defined. In this study, we investigated the function of...

Health and Economic Burden of Obesity in Brazil

Introduction Higher and lower-middle income countries are increasingly affected by obesity. Obesity-related diseases are placing a substantial health and economic burden on Brazil. Our aim is to measure the future consequences of these trends on the associated disease burden and health care costs. Method A previously developed micro-simulation model is used to project the extent...

High Rates of Obesity and Non-Communicable Diseases Predicted across Latin America

Non-communicable diseases (NCDs) such as cardiovascular disease and stroke are a major public health concern across Latin America. A key modifiable risk factor for NCDs is overweight and obesity highlighting the need for policy to reduce prevalence rates and ameliorate rising levels of NCDs. A cross-sectional regression analysis was used to project BMI and related disease trends...

Modelling human balance using switched systems with linear feedback control

Piotr Kowalczyk () Paul Glendinning Martin Brown Gustavo Medrano-Cerda Houman Dallali Jonathan Shapiro Receive free email alerts when new articles cite this article - sign up in the box at the top

Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats

Lawrence Recht 1 J. Martin Brown () 1 0 These are co-first authors 1 Department of Radiation Oncology, Stanford University , Stanford, CA (S-C .L., R.A., S.B.C., F.L. , J.S., J.M.B.); Department of Neurology

Intrinsic Capability of Budding Yeast Cofilin to Promote Turnover of Tropomyosin-Bound Actin Filaments

The ability of actin filaments to function in cell morphogenesis and motility is closely coupled to their dynamic properties. Yeast cells contain two prominent actin structures, cables and patches, both of which are rapidly assembled and disassembled. Although genetic studies have shown that rapid actin turnover in patches and cables depends on cofilin, how cofilin might control...

Information-theoretic sensitivity analysis: a general method for credit assignment in complex networks

Niklas Ldtke () Stefano Panzeri Martin Brown David S Broomhead Joshua Knowles Marcelo A Montemurro Douglas B Kell 0 Faculty of Life Sciences 1 The Manchester Interdisciplinary Biocentre 2 School of

Use of Three-Dimensional Tissue Cultures to Model Extravascular Transport and Predict In Vivo Activity of Hypoxia-Targeted Anticancer Drugs

or the decision to submit it for publication. J. Martin Brown is conducting research funded by Sanofi-Aventis, which has licensed tirapazamine. We thank Jane Botting, Rachel Chapman, Anna Chappell

Cost Comparison of Mastectomy Versus Breast-Conserving Therapy for Early-Stage Breast Cancer

Background: Choice of treatment for early-stage breast cancer depends on many factors, including the size and stage of the cancer, the woman's age, comorbid conditions, and perhaps the costs of treatment. We compared the costs of all medical care for women with early-stage breast cancer cases treated by breast-conserving therapy (BCT) or mastectomy. Methods: A total of 1675 women...

Integrating phenotypic and expression profiles to map arsenic-response networks

Charles J Tucker Changchun Deng Cynthia A Afshari J Martin Brown Trey Ideker Bennett Van Houten Background: Arsenic is a nonmutagenic carcinogen affecting millions of people. The cellular impact of this

Development of Investigational Radiation Modifiers

Institute; J. Martin Brown, Ph.D., Stanford Medical Center, Stanford University; Hak Choy, M.D., Department of Radiation Oncology, Vanderbilt University Medical Center; Adam Dicker, M.D., Ph.D., Department of

LAB-EXPERIMENTAL (PRE-CLINICAL) THERAPEUTICS AND PHARMACOLOGY

TUMORS Martin Brown; Stanford University, Palo Alto, CA With current treatment of glioblastomas (GBM), 85% of the tumors recur within the field of high-dose radiation. This tumor recurrence requires